Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms
出版年份 2019 全文链接
标题
Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms
作者
关键词
-
出版物
NATURE CELL BIOLOGY
Volume 21, Issue 9, Pages 1113-1126
出版商
Springer Science and Business Media LLC
发表日期
2019-08-27
DOI
10.1038/s41556-019-0373-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis
- (2019) Max D. Wellenstein et al. NATURE
- Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
- (2017) Lin Tian et al. NATURE
- The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states
- (2016) M. J. Toneff et al. BMC BIOLOGY
- One microenvironment does not fit all: heterogeneity beyond cancer cells
- (2016) Ik Sun Kim et al. CANCER AND METASTASIS REVIEWS
- Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
- (2016) Willy Hugo et al. CELL
- Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma
- (2016) Y. Lou et al. CLINICAL CANCER RESEARCH
- Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers
- (2016) Adam D. Pfefferle et al. Disease Models & Mechanisms
- Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types
- (2016) Michael D. Iglesia et al. JNCI-Journal of the National Cancer Institute
- Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells
- (2016) Olivier De Henau et al. NATURE
- PI3Kγ is a molecular switch that controls immune suppression
- (2016) Megan M. Kaneda et al. NATURE
- Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation
- (2016) Thomas Welte et al. NATURE CELL BIOLOGY
- Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps
- (2016) J. Park et al. Science Translational Medicine
- Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
- (2016) Vincenzo Bronte et al. Nature Communications
- Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study
- (2016) H. Raza Ali et al. PLOS MEDICINE
- Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types
- (2016) Michael D. Iglesia et al. JNCI-Journal of the National Cancer Institute
- Neutrophils support lung colonization of metastasis-initiating breast cancer cells
- (2015) Stefanie K. Wculek et al. NATURE
- IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis
- (2015) Seth B. Coffelt et al. NATURE
- The prognostic landscape of genes and infiltrating immune cells across human cancers
- (2015) Andrew J Gentles et al. NATURE MEDICINE
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils
- (2015) Amy-Jo Casbon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plasticity in Tumor-Promoting Inflammation: Impairment of Macrophage Recruitment Evokes a Compensatory Neutrophil Response
- (2015) Jessica C. Pahler et al. NEOPLASIA
- Prognostic B-cell Signatures Using mRNA-Seq in Patients with Subtype-Specific Breast and Ovarian Cancer
- (2014) M. D. Iglesia et al. CLINICAL CANCER RESEARCH
- TSG-6 Inhibits Neutrophil Migration via Direct Interaction with the Chemokine CXCL8
- (2014) D. P. Dyer et al. JOURNAL OF IMMUNOLOGY
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- Breast cancer as a systemic disease: a view of metastasis
- (2013) A. J. Redig et al. JOURNAL OF INTERNAL MEDICINE
- CSF-1R inhibition alters macrophage polarization and blocks glioma progression
- (2013) Stephanie M Pyonteck et al. NATURE MEDICINE
- Bone Marrow–Derived Gr1 + Cells Can Generate a Metastasis-Resistant Microenvironment Via Induced Secretion of Thrombospondin-1
- (2013) Raúl Catena et al. Cancer Discovery
- Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis
- (2013) Srikanth Nagalla et al. GENOME BIOLOGY
- Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
- (2012) Douglas Hanahan et al. CANCER CELL
- The Transcription Factor Jdp2 Controls Bone Homeostasis and Antibacterial Immunity by Regulating Osteoclast and Neutrophil Differentiation
- (2012) Kenta Maruyama et al. IMMUNITY
- The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
- (2012) Christina Curtis et al. NATURE
- Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
- (2012) Emmanuel L Gautier et al. NATURE IMMUNOLOGY
- Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils
- (2012) Zvi G. Fridlender et al. PLoS One
- Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung
- (2011) Zvi Granot et al. CANCER CELL
- Macrophages in cancer and infectious diseases: the ‘good’ and the ‘bad’
- (2011) Chiara Porta et al. Immunotherapy
- Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
- (2011) Brian D. Lehmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells
- (2011) J. I. Herschkowitz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
- (2011) R. D. Schreiber et al. SCIENCE
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- Tumors as Organs: Complex Tissues that Interface with the Entire Organism
- (2010) Mikala Egeblad et al. DEVELOPMENTAL CELL
- Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps
- (2010) Venizelos Papayannopoulos et al. JOURNAL OF CELL BIOLOGY
- Metastatic Behavior of Breast Cancer Subtypes
- (2010) Hagen Kennecke et al. JOURNAL OF CLINICAL ONCOLOGY
- Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
- (2010) J. H. Taube et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes
- (2010) M. Kowanetz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function
- (2010) Thomas Condamine et al. TRENDS IN IMMUNOLOGY
- Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN
- (2009) Zvi G. Fridlender et al. CANCER CELL
- Subtypes of Breast Cancer Show Preferential Site of Relapse
- (2008) M. Smid et al. CANCER RESEARCH
- A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
- (2008) Ulrike Burk et al. EMBO REPORTS
- The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2
- (2008) Manav Korpal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Breast Cancer Subtype Approximated by Estrogen Receptor, Progesterone Receptor, and HER-2 Is Associated With Local and Distant Recurrence After Breast-Conserving Therapy
- (2008) Paul L. Nguyen et al. JOURNAL OF CLINICAL ONCOLOGY
- The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
- (2008) Philip A. Gregory et al. NATURE CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search