Synaptic proximity enables NMDAR signalling to promote brain metastasis

ALK7 Signaling Manifests a Homeostatic Tissue Barrier That Is Abrogated during Tumorigenesis and Metastasis

(2019) Iacovos P. Michael et al.   DEVELOPMENTAL CELL

GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth

(2018) Leanne Li et al.   CANCER CELL

Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function

(2018) Aaron D. Levy et al.   Cell Reports

Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis

(2017) Jeff A. Stogsdill et al.   NATURE

Autocrine, paracrine and necrotic NMDA receptor signalling in mouse pancreatic neuroendocrine tumour cells

(2017) Hugh P. C. Robinson et al.   Open Biology

Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine

(2016) Kimberly J. Briggs et al.   CELL

Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer

(2016) Qing Chen et al.   NATURE

Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

(2016) Nicholas L Weilinger et al.   NATURE NEUROSCIENCE

Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit

(2015) Ksenya Shchors et al.   CANCER CELL

Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

(2015) Giovanni Ciriello et al.   CELL

Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis

(2014) Manuel Valiente et al.   CELL

Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

(2014) Lisa Sevenich et al.   NATURE CELL BIOLOGY

Human breast cancer metastases to the brain display GABAergic properties in the neural niche

(2014) J. Neman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NR2B Phosphorylation at Tyrosine 1472 Contributes to Brain Injury in a Rodent Model of Neonatal Hypoxia-Ischemia

(2014) Renatta Knox et al.   STROKE

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Origins of Metastatic Traits

(2013) Sakari Vanharanta et al.   CANCER CELL

Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion

(2013) Leanne Li et al.   CELL

CNS Metastases in Breast Cancer: Old Challenge, New Frontiers

(2013) N. U. Lin et al.   CLINICAL CANCER RESEARCH

An Optimized microRNA Backbone for Effective Single-Copy RNAi

(2013) Christof Fellmann et al.   Cell Reports

TrakEM2 Software for Neural Circuit Reconstruction

(2012) Albert Cardona et al.   PLoS One

Ultrastructure of Synapses in the Mammalian Brain

(2012) K. M. Harris et al.   Cold Spring Harbor Perspectives in Biology

Effects of divalent cations on slow unblock of native NMDA receptors in mouse neocortical pyramidal neurons

(2011) Nam-Kyung Kim et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A Genomic Predictor of Response and Survival Following Taxane-Anthracycline Chemotherapy for Invasive Breast Cancer

(2011) Christos Hatzis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Glutamate release by primary brain tumors induces epileptic activity

(2011) Susan C Buckingham et al.   NATURE MEDICINE

Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis

(2011) E. S. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capturing Changes in the Brain Microenvironment during Initial Steps of Breast Cancer Brain Metastasis

(2010) Mihaela Lorger et al.   AMERICAN JOURNAL OF PATHOLOGY

Impairment of CaMKII activation and attenuation of neuropathic pain in mice lacking NR2B phosphorylated at Tyr1472

(2010) Shinji Matsumura et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE