Plant Leucine-Rich Repeat Receptor Kinase (LRR-RK): Structure, Ligand Perception, and Activation Mechanism

Cysteine-rich peptides promote interspecific genetic isolation in Arabidopsis

(2019) Sheng Zhong et al.   SCIENCE

The Extracellular Domain of Pollen Receptor Kinase 3 is structurally similar to the SERK family of co-receptors

(2018) Sayan Chakraborty et al.   Scientific Reports

Regulation of plant peptide hormones and growth factors by post-translational modification

(2018) N. Stührwohldt et al.   PLANT BIOLOGY

A receptor-like protein acts as a specificity switch for the regulation of stomatal development

(2017) Guangzhong Lin et al.   GENES & DEVELOPMENT

Diverse Peptide Hormones Affecting Root Growth Identified in theMedicago truncatulaSecreted Peptidome

(2017) Neha Patel et al.   MOLECULAR & CELLULAR PROTEOMICS

Root diffusion barrier control by a vasculature-derived peptide binding to the SGN3 receptor

(2017) Verónica G. Doblas et al.   SCIENCE

A peptide hormone required for Casparian strip diffusion barrier formation in Arabidopsis roots

(2017) Takuya Nakayama et al.   SCIENCE

Structural basis for receptor recognition of pollen tube attraction peptides

(2017) Xiaoxiao Zhang et al.   Nature Communications

Differential CLE peptide perception by plant receptors implicated from structural and functional analyses of TDIF-TDR interactions

(2017) Zhijie Li et al.   PLoS One

RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana

(2016) Yang Ou et al.   CELL RESEARCH

Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth

(2016) Wen Song et al.   CELL RESEARCH

Crystal structure of PXY-TDIF complex reveals a conserved recognition mechanism among CLE peptide-receptor pairs

(2016) Heqiao Zhang et al.   CELL RESEARCH

SERK Family Receptor-like Kinases Function as Co-receptors with PXY for Plant Vascular Development

(2016) Heqiao Zhang et al.   Molecular Plant

A receptor heteromer mediates the male perception of female attractants in plants

(2016) Tong Wang et al.   NATURE

Tip-localized receptors control pollen tube growth and LURE sensing in Arabidopsis

(2016) Hidenori Takeuchi et al.   NATURE

Identification of three LRR-RKs involved in perception of root meristem growth factor inArabidopsis

(2016) Hidefumi Shinohara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligand-Induced Receptor-like Kinase Complex Regulates Floral Organ Abscission in Arabidopsis

(2016) Xiangzong Meng et al.   Cell Reports

Mechanistic insight into a peptide hormone signaling complex mediating floral organ abscission

(2016) Julia Santiago et al.   eLife

Differential Function of Arabidopsis SERK Family Receptor-like Kinases in Stomatal Patterning

(2015) Xiangzong Meng et al.   CURRENT BIOLOGY

Plant stem cell maintenance by transcriptional cross-regulation of related receptor kinases

(2015) Z. L. Nimchuk et al.   DEVELOPMENT

Genome-wide annotation and characterization of CLAVATA/ESR (CLE) peptide hormones of soybean (Glycine max) and common bean (Phaseolus vulgaris), and their orthologues ofArabidopsis thaliana

(2015) April H. Hastwell et al.   JOURNAL OF EXPERIMENTAL BOTANY

On the Origin of SERKs: Bioinformatics Analysis of the Somatic Embryogenesis Receptor Kinases

(2015) Marije aan den Toorn et al.   Molecular Plant

Allosteric receptor activation by the plant peptide hormone phytosulfokine

(2015) Jizong Wang et al.   NATURE

Primary transcripts of microRNAs encode regulatory peptides

(2015) Dominique Lauressergues et al.   NATURE

BAM 1 and RECEPTOR-LIKE PROTEIN KINASE 2 constitute a signaling pathway and modulate CLE peptide-triggered growth inhibition inArabidopsisroot

(2015) Noriko Shimizu et al.   NEW PHYTOLOGIST

The Plant Peptidome: An Expanding Repertoire of Structural Features and Biological Functions

(2015) Patrizia Tavormina et al.   PLANT CELL

Phytosulfokine Regulates Growth in Arabidopsis through a Response Module at the Plasma Membrane That Includes CYCLIC NUCLEOTIDE-GATED CHANNEL17, H+-ATPase, and BAK1

(2015) Friederike Ladwig et al.   PLANT CELL

A comprehensive strategy for identifying long-distance mobile peptides in xylem sap

(2015) Satoru Okamoto et al.   PLANT JOURNAL

Reevaluation of the CLV3-receptor interaction in the shoot apical meristem: dissection of the CLV3 signaling pathway from a direct ligand-binding point of view

(2015) Hidefumi Shinohara et al.   PLANT JOURNAL

Posttranslationally Modified Small-Peptide Signals in Plants

(2014) Yoshikatsu Matsubayashi   Annual Review of Plant Biology

Structural basis for recognition of an endogenous peptide by the plant receptor kinase PEPR1

(2014) Jiao Tang et al.   CELL RESEARCH

Quantitative Peptidomics Study Reveals That a Wound-Induced Peptide from PR-1 Regulates Immune Signaling in Tomato

(2014) Y.-L. Chen et al.   PLANT CELL

Tools and Strategies to Match Peptide-Ligand Receptor Pairs

(2014) M. A. Butenko et al.   PLANT CELL

Crystal structures of the phosphorylated BRI1 kinase domain and implications for brassinosteroid signal initiation

(2014) Daniel Bojar et al.   PLANT JOURNAL

Receptor kinase-mediated control of primary active proton pumping at the plasma membrane

(2014) Anja T. Fuglsang et al.   PLANT JOURNAL

Central Cell-Derived Peptides Regulate Early Embryo Patterning in Flowering Plants

(2014) L. M. Costa et al.   SCIENCE

The EGFR Family: Not So Prototypical Receptor Tyrosine Kinases

(2014) M. A. Lemmon et al.   Cold Spring Harbor Perspectives in Biology

Plant GSK3 proteins regulate xylem cell differentiation downstream of TDIF–TDR signalling

(2014) Yuki Kondo et al.   Nature Communications

Structure of the OsSERK2 leucine-rich repeat extracellular domain

(2014) Ryan McAndrew et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Endodermis

(2013) Niko Geldner   Annual Review of Plant Biology

Genome-wide identification, characterization and expression analysis of populus leucine-rich repeat receptor-like protein kinase genes

(2013) Yanjun Zan et al.   BMC GENOMICS

The Arabidopsis LRR-RLK, PXC1, is a regulator of secondary wall formation correlated with the TDIF-PXY/TDR-WOX4 signaling pathway

(2013) Jiehua Wang et al.   BMC PLANT BIOLOGY

Structure reveals that BAK1 as a co-receptor recognizes the BRI1-bound brassinolide

(2013) Yadong Sun et al.   CELL RESEARCH

The receptor-like kinases GSO1 and GSO2 together regulate root growth inarabidopsisthrough control of cell division and cell fate specification

(2013) Adriana Racolta et al.   DEVELOPMENTAL DYNAMICS

Diverse Roles ofERECTAFamily Genes in Plant Development

(2013) Elena D. Shpak   Journal of Integrative Plant Biology

Regulation of plant translation by upstream open reading frames

(2013) Albrecht G. von Arnim et al.   PLANT SCIENCE

In silico Platform for Prediction of N-, O- and C-Glycosites in Eukaryotic Protein Sequences

(2013) Jagat Singh Chauhan et al.   PLoS One

Floral organ abscission peptide IDA and its HAE/HSL2 receptors control cell separation during lateral root emergence

(2013) R. P. Kumpf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small open reading frames associated with morphogenesis are hidden in plant genomes

(2013) K. Hanada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BIK1 interacts with PEPRs to mediate ethylene-induced immunity

(2013) Z. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for flg22-Induced Activation of the Arabidopsis FLS2-BAK1 Immune Complex

(2013) Y. Sun et al.   SCIENCE

Molecular Mechanism for Plant Steroid Receptor Activation by Somatic Embryogenesis Co-Receptor Kinases

(2013) J. Santiago et al.   SCIENCE

Crystal structure of a plant leucine rich repeat protein with two island domains

(2013) Wen Song et al.   Science China-Life Sciences

Root-derived CLE glycopeptides control nodulation by direct binding to HAR1 receptor kinase

(2013) Satoru Okamoto et al.   Nature Communications

Mechanisms of Stomatal Development

(2012) Lynn Jo Pillitteri et al.   Annual Review of Plant Biology

GOLVEN Secretory Peptides Regulate Auxin Carrier Turnover during Plant Gravitropic Responses

(2012) Ryan Whitford et al.   DEVELOPMENTAL CELL

Direct interaction of ligand-receptor pairs specifying stomatal patterning

(2012) J. S. Lee et al.   GENES & DEVELOPMENT

Role of Cysteine Residues and Disulfide Bonds in the Activity of a Legume Root Nodule-specific, Cysteine-rich Peptide

(2012) Andreas F. Haag et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AtPRK2 Promotes ROP1 Activation via RopGEFs in the Control of Polarized Pollen Tube Growth

(2012) Fang Chang et al.   Molecular Plant

Finding the missing links in EGFR

(2012) Nicholas J Bessman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chemical Synthesis of Arabidopsis CLV3 Glycopeptide Reveals the Impact of Hydroxyproline Arabinosylation on Peptide Conformation and Activity

(2012) Hidefumi Shinohara et al.   PLANT AND CELL PHYSIOLOGY

Phytosulfokine control of growth occurs in the epidermis, is likely to be non-cell autonomous and is dependent on brassinosteroids

(2012) Jens Hartmann et al.   PLANT JOURNAL

The tyrosine-sulfated peptide receptors PSKR1 and PSY1R modify the immunity of Arabidopsis to biotrophic and necrotrophic pathogens in an antagonistic manner

(2012) Stephen Mosher et al.   PLANT JOURNAL

Regulation of inflorescence architecture by intertissue layer ligand-receptor communication between endodermis and phloem

(2012) N. Uchida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CLE-like (CLEL) peptides control the pattern of root growth and lateral root development in Arabidopsis

(2012) L. Meng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Species-Specific Cluster of Defensin-Like Genes Encodes Diffusible Pollen Tube Attractants in Arabidopsis

(2012) Hidenori Takeuchi et al.   PLOS BIOLOGY

Peptide Signaling in Plant Development

(2011) Leron Katsir et al.   CURRENT BIOLOGY

Sequence and function of basic helix-loop-helix proteins required for stomatal development in Arabidopsis are deeply conserved in land plants

(2011) Cora A. MacAlister et al.   EVOLUTION & DEVELOPMENT

CLAVATA Signaling Pathway Receptors ofArabidopsisRegulate Cell Proliferation in Fruit Organ Formation as well as in Meristems

(2011) Amanda R. Durbak et al.   GENETICS

Cysteine-Rich Peptides (CRPs) mediate diverse aspects of cell-cell communication in plant reproduction and development

(2011) E. Marshall et al.   JOURNAL OF EXPERIMENTAL BOTANY

Structural insight into brassinosteroid perception by BRI1

(2011) Ji She et al.   NATURE

Structural basis of steroid hormone perception by the receptor kinase BRI1

(2011) Michael Hothorn et al.   NATURE

Diverse Functions of Plant Peptides: Entering a New Phase

(2011) H. Fukuda et al.   PLANT AND CELL PHYSIOLOGY

Generation of Signaling Specificity inArabidopsisby Spatially Restricted Buffering of Ligand–Receptor Interactions

(2011) Emily B. Abrash et al.   PLANT CELL

Differentiation of Arabidopsis Guard Cells: Analysis of the Networks Incorporating the Basic Helix-Loop-Helix Transcription Factor, FAMA

(2011) C. Hachez et al.   PLANT PHYSIOLOGY

Protein and metabolite composition of xylem sap from field-grown soybeans (Glycine max)

(2011) Hari B. Krishnan et al.   PLANTA

Genome-Wide Identification, Characterization and Phylogenetic Analysis of the Rice LRR-Kinases

(2011) Xinli Sun et al.   PLoS One

Phytosulfokine-α Controls Hypocotyl Length and Cell Expansion in Arabidopsis thaliana through Phytosulfokine Receptor 1

(2011) Nils Stührwohldt et al.   PLoS One

The Structural Biology of Toll-like Receptors

(2011) Istvan Botos et al.   STRUCTURE

Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana

(2010) Xiaoping Gou et al.   BMC GENOMICS

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

The EVERSHED receptor-like kinase modulates floral organ shedding in Arabidopsis

(2010) M. E. Leslie et al.   DEVELOPMENT

The PXY-CLE41 receptor ligand pair defines a multifunctional pathway that controls the rate and orientation of vascular cell division

(2010) J. P. Etchells et al.   DEVELOPMENT

RPK2 is an essential receptor-like kinase that transmits the CLV3 signal in Arabidopsis

(2010) A. Kinoshita et al.   DEVELOPMENT

Perception of theArabidopsisDanger Signal Peptide 1 Involves the Pattern Recognition ReceptorAtPEPR1 and Its Close HomologueAtPEPR2

(2010) Elzbieta Krol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plant twitter: ligands under 140 amino acids enforcing stomatal patterning

(2010) Amanda L. Rychel et al.   JOURNAL OF PLANT RESEARCH

Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases

(2010) Jae Hyun Bae et al.   MOLECULES AND CELLS

Mitogen-Activated Protein Kinase Regulated by the CLAVATA Receptors Contributes to Shoot Apical Meristem Homeostasis

(2010) Shigeyuki Betsuyaku et al.   PLANT AND CELL PHYSIOLOGY

Post-Translational Modifications in Secreted Peptide Hormones in Plants

(2010) Y. Matsubayashi   PLANT AND CELL PHYSIOLOGY

PEPR2 Is a Second Receptor for the Pep1 and Pep2 Peptides and Contributes to Defense Responses in Arabidopsis

(2010) Y. Yamaguchi et al.   PLANT CELL

TDIF Peptide Signaling Regulates Vascular Stem Cell Proliferation via the WOX4 Homeobox Gene in Arabidopsis

(2010) Y. Hirakawa et al.   PLANT CELL

SacRALF1, a peptide signal from the grass sugarcane (Saccharum spp.), is potentially involved in the regulation of tissue expansion

(2010) Fabiana B. Mingossi et al.   PLANT MOLECULAR BIOLOGY

Disease resistance signature of the leucine-rich repeat receptor-like kinase genes in four plant species

(2010) Ping Tang et al.   PLANT SCIENCE

Secreted Peptide Signals Required for Maintenance of Root Stem Cell Niche in Arabidopsis

(2010) Y. Matsuzaki et al.   SCIENCE

Regulation of Cell Death and Innate Immunity by Two Receptor-like Kinases in Arabidopsis

(2009) Minghui Gao et al.   Cell Host & Microbe

Cyclotides: macrocyclic peptides with applications in drug design and agriculture

(2009) David J. Craik et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Orthologs of Arabidopsis thaliana stomatal bHLH genes and regulation of stomatal development in grasses

(2009) T. Liu et al.   DEVELOPMENT

Receptor quality control in the endoplasmic reticulum for plant innate immunity

(2009) Yusuke Saijo et al.   EMBO JOURNAL

Structure and function of VEGF receptors

(2009) Edward Stuttfeld et al.   IUBMB LIFE

Pattern Recognition Receptors RequireN-Glycosylation to Mediate Plant Immunity

(2009) Heidrun Häweker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Origin and Diversification of Basic-Helix-Loop-Helix Proteins in Plants

(2009) N. Pires et al.   MOLECULAR BIOLOGY AND EVOLUTION

Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells

(2009) Satohiro Okuda et al.   NATURE

Receptor-like kinases shape the plant

(2009) Ive De Smet et al.   NATURE CELL BIOLOGY

A glycopeptide regulating stem cell fate in Arabidopsis thaliana

(2009) Kentaro Ohyama et al.   Nature Chemical Biology

Novel and Expanded Roles for MAPK Signaling in Arabidopsis Stomatal Cell Fate Revealed by Cell Type-Specific Manipulations

(2009) G. R. Lampard et al.   PLANT CELL

Identification of tyrosylprotein sulfotransferase in Arabidopsis

(2009) R. Komori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific ER quality control components required for biogenesis of the plant innate immune receptor EFR

(2009) J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CLE peptide signaling during plant development

(2009) Guodong Wang et al.   PROTOPLASMA

Plant peptides in signalling: looking for new partners

(2009) Melinka A. Butenko et al.   TRENDS IN PLANT SCIENCE

ArabidopsisMAPKs: a complex signalling network involved in multiple biological processes

(2008) Jean Colcombet et al.   BIOCHEMICAL JOURNAL

The leucine-rich repeat structure

(2008) J. Bella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays

(2008) S. C. Popescu et al.   GENES & DEVELOPMENT

BAM Receptors Regulate Stem Cell Specification and Organ Development Through Complex Interactions With CLAVATA Signaling

(2008) B. J. DeYoung et al.   GENETICS

PSK-α promotes root growth in Arabidopsis

(2008) Anke Kutschmar et al.   NEW PHYTOLOGIST

PhytAMP: a database dedicated to antimicrobial plant peptides

(2008) R. Hammami et al.   NUCLEIC ACIDS RESEARCH

Structure–activity studies of AtPep1, a plant peptide signal involved in the innate immune response

(2008) Gregory Pearce et al.   PEPTIDES

The bHLH Protein, MUTE, Controls Differentiation of Stomata and the Hydathode Pore in Arabidopsis

(2008) Lynn Jo Pillitteri et al.   PLANT AND CELL PHYSIOLOGY

The EPIP Peptide of INFLORESCENCE DEFICIENT IN ABSCISSION Is Sufficient to Induce Abscission in Arabidopsis through the Receptor-Like Kinases HAESA and HAESA-LIKE2

(2008) G.-E. Stenvik et al.   PLANT CELL

SCREAM/ICE1 and SCREAM2 Specify Three Cell-State Transitional Steps Leading to Arabidopsis Stomatal Differentiation

(2008) M. M. Kanaoka et al.   PLANT CELL

Two Leucine-Rich Repeat Receptor Kinases Mediate Signaling, Linking Cell Wall Biosynthesis and ACC Synthase in Arabidopsis

(2008) S.-L. Xu et al.   PLANT CELL

The Receptor Kinase CORYNE of Arabidopsis Transmits the Stem Cell-Limiting Signal CLAVATA3 Independently of CLAVATA1

(2008) R. Muller et al.   PLANT CELL

Comparative Analyses of Arabidopsis complex glycan1 Mutants and Genetic Interaction with staurosporin and temperature sensitive3a

(2008) J. Frank et al.   PLANT PHYSIOLOGY

A Genome-Wide Functional Investigation into the Roles of Receptor-Like Proteins in Arabidopsis

(2008) G. Wang et al.   PLANT PHYSIOLOGY

AtSERK1 expression precedes and coincides with early somatic embryogenesis in Arabidopsis thaliana

(2008) Jan Salaj et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

TOO MANY MOUTHS promotes cell fate progression in stomatal development of Arabidopsis stems

(2008) Neela S. Bhave et al.   PLANTA

Plant CLE peptides from two distinct functional classes synergistically induce division of vascular cells

(2008) R. Whitford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-cell-autonomous control of vascular stem cell fate by a CLE peptide/receptor system

(2008) Y. Hirakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of floral organ abscission in Arabidopsis thaliana

(2008) S. K. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arabidopsis Stomatal Initiation Is Controlled by MAPK-Mediated Regulation of the bHLH SPEECHLESS

(2008) G. R. Lampard et al.   SCIENCE

Arabidopsis CLV3 Peptide Directly Binds CLV1 Ectodomain

(2008) M. Ogawa et al.   SCIENCE