Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion

Nucleus Accumbens Subnuclei Regulate Motivated Behavior via Direct Inhibition and Disinhibition of VTA Dopamine Subpopulations

(2018) Hongbin Yang et al.   NEURON

Ventral pallidum encodes relative reward value earlier and more robustly than nucleus accumbens

(2018) David Ottenheimer et al.   Nature Communications

Ventrolateral Striatal Medium Spiny Neurons Positively Regulate Food-Incentive, Goal-Directed Behavior Independently of D1 and D2 Selectivity

(2017) Akiyo Natsubori et al.   JOURNAL OF NEUROSCIENCE

Circuit specificity in the inhibitory architecture of the VTA regulates cocaine-induced behavior

(2017) Nicholas J Edwards et al.   NATURE NEUROSCIENCE

Ventral tegmental area: cellular heterogeneity, connectivity and behaviour

(2017) Marisela Morales et al.   NATURE REVIEWS NEUROSCIENCE

Pathway- and Cell-Specific Kappa-Opioid Receptor Modulation of Excitation-Inhibition Balance Differentially Gates D1 and D2 Accumbens Neuron Activity

(2017) Hugo A. Tejeda et al.   NEURON

Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits

(2017) Bárbara Coimbra et al.   eLife

Direct and indirect dorsolateral striatum pathways reinforce different action strategies

(2016) Ana M. Vicente et al.   CURRENT BIOLOGY

Convergence of Reinforcing and Anhedonic Cocaine Effects in the Ventral Pallidum

(2016) Meaghan Creed et al.   NEURON

Reappraising striatal D1- and D2-neurons in reward and aversion

(2016) Carina Soares-Cunha et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation

(2016) Carina Soares-Cunha et al.   Nature Communications

Nucleus Accumbens Medium Spiny Neuron Subtypes Mediate Depression-Related Outcomes to Social Defeat Stress

(2015) T. Chase Francis et al.   BIOLOGICAL PSYCHIATRY

Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons

(2015) J. M. Ehrich et al.   JOURNAL OF NEUROSCIENCE

Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections

(2015) Yonatan M Kupchik et al.   NATURE NEUROSCIENCE

Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and Reward

(2015) Ream Al-Hasani et al.   NEURON

Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

(2015) Rosemary C. Bagot et al.   Nature Communications

Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking

(2014) Stephen V Mahler et al.   NATURE NEUROSCIENCE

Basal ganglia subcircuits distinctively encode the parsing and concatenation of action sequences

(2014) Xin Jin et al.   NATURE NEUROSCIENCE

Kappa Opioid Receptor Activation Potentiates the Cocaine-Induced Increase in Evoked Dopamine Release Recorded In Vivo in the Mouse Nucleus Accumbens

(2014) Jonathan M Ehrich et al.   NEUROPSYCHOPHARMACOLOGY

Aversive behavior induced by optogenetic inactivation of ventral tegmental area dopamine neurons is mediated by dopamine D2 receptors in the nucleus accumbens

(2014) T. Danjo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct prestimulus and poststimulus activation of VTA neurons correlates with stimulus detection

(2013) Nelson K. B. Totah et al.   JOURNAL OF NEUROPHYSIOLOGY

Opioid Modulation of Ventral Pallidal Afferents to Ventral Tegmental Area Neurons

(2013) G. O. Hjelmstad et al.   JOURNAL OF NEUROSCIENCE

Concurrent activation of striatal direct and indirect pathways during action initiation

(2013) Guohong Cui et al.   NATURE

Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use

(2013) Roland Bock et al.   NATURE NEUROSCIENCE

The brain reward circuitry in mood disorders

(2013) Scott J. Russo et al.   NATURE REVIEWS NEUROSCIENCE

Cocaine Disinhibits Dopamine Neurons by Potentiation of GABA Transmission in the Ventral Tegmental Area

(2013) C. Bocklisch et al.   SCIENCE

From prediction error to incentive salience: mesolimbic computation of reward motivation

(2012) Kent C. Berridge   EUROPEAN JOURNAL OF NEUROSCIENCE

Input-specific control of reward and aversion in the ventral tegmental area

(2012) Stephan Lammel et al.   NATURE

Transient stimulation of distinct subpopulations of striatal neurons mimics changes in action value

(2012) Lung-Hao Tai et al.   NATURE NEUROSCIENCE

Distinct roles for direct and indirect pathway striatal neurons in reinforcement

(2012) Alexxai V Kravitz et al.   NATURE NEUROSCIENCE

Activation of VTA GABA Neurons Disrupts Reward Consumption

(2012) Ruud van Zessen et al.   NEURON

GABA Neurons of the VTA Drive Conditioned Place Aversion

(2012) Kelly R. Tan et al.   NEURON

Are you or aren’t you? Challenges associated with physiologically identifying dopamine neurons

(2012) Mark A. Ungless et al.   TRENDS IN NEUROSCIENCES

Nucleus Accumbens Medium Spiny Neurons Target Non-Dopaminergic Neurons in the Ventral Tegmental Area

(2011) Y. Xia et al.   JOURNAL OF NEUROSCIENCE

Optogenetic Interrogation of Dopaminergic Modulation of the Multiple Phases of Reward-Seeking Behavior

(2011) A. R. Adamantidis et al.   JOURNAL OF NEUROSCIENCE

Projection-Specific Modulation of Dopamine Neuron Synapses by Aversive and Rewarding Stimuli

(2011) Stephan Lammel et al.   NEURON

Dopamine in Motivational Control: Rewarding, Aversive, and Alerting

(2010) Ethan S. Bromberg-Martin et al.   NEURON

Distinct Roles of Synaptic Transmission in Direct and Indirect Striatal Pathways to Reward and Aversive Behavior

(2010) Takatoshi Hikida et al.   NEURON

Juxtacellular labeling of tonically active neurons and phasically active neurons in the rat striatum

(2010) H. Inokawa et al.   NEUROSCIENCE

Cell Type-Specific Loss of BDNF Signaling Mimics Optogenetic Control of Cocaine Reward

(2010) M. K. Lobo et al.   SCIENCE

Reduced Caudate and Nucleus Accumbens Response to Rewards in Unmedicated Individuals With Major Depressive Disorder

(2009) Diego A. Pizzagalli et al.   AMERICAN JOURNAL OF PSYCHIATRY

Beyond the Reward Pathway: Coding Reward Magnitude and Error in the Rat Subthalamic Nucleus

(2009) Sylvie Lardeux et al.   JOURNAL OF NEUROPHYSIOLOGY

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

(2009) H.-C. Tsai et al.   SCIENCE

Dorsomedial Prefrontal Cortex Contribution to Behavioral and Nucleus Accumbens Neuronal Responses to Incentive Cues

(2008) A. Ishikawa et al.   JOURNAL OF NEUROSCIENCE

Biological substrates of reward and aversion: A nucleus accumbens activity hypothesis

(2008) William A. Carlezon et al.   NEUROPHARMACOLOGY