标题
Neoantigen vaccine: an emerging tumor immunotherapy
作者
关键词
Neoantigen, Tumor, Vaccine, Malignancy, Immunotherapy
出版物
Molecular Cancer
Volume 18, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-08-23
DOI
10.1186/s12943-019-1055-6
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape
- (2019) Xianjie Jiang et al. Molecular Cancer
- Analysis of status and countermeasures of cancer incidence and mortality in China
- (2019) Chunchun Wu et al. Science China-Life Sciences
- Natural killer group 2D receptor and its ligands in cancer immune escape
- (2019) Shixin Duan et al. Molecular Cancer
- Effects and mechanisms of innate immune molecules on inhibiting nasopharyngeal carcinoma
- (2019) Fang Xiong et al. CHINESE MEDICAL JOURNAL
- Induction of neoantigen-reactive T cells from healthy donors
- (2019) Muhammad Ali et al. Nature Protocols
- NeoPredPipe: high-throughput neoantigen prediction and recognition potential pipeline
- (2019) Ryan O. Schenck et al. BMC BIOINFORMATICS
- Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses
- (2019) Anthony E. Zamora et al. Science Translational Medicine
- Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers
- (2019) Maria R. Parkhurst et al. Cancer Discovery
- Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer
- (2019) Song Liu et al. Journal for ImmunoTherapy of Cancer
- Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes
- (2018) Marvin H. Gee et al. CELL
- Role of metabolism in cancer cell radioresistance and radiosensitization methods
- (2018) Le Tang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities
- (2018) Yazhuo Zhang et al. Molecular Cancer
- LncRNAs regulate the cytoskeleton and related Rho/ROCK signaling in cancer metastasis
- (2018) Yanyan Tang et al. Molecular Cancer
- Strelka2: fast and accurate calling of germline and somatic variants
- (2018) Sangtae Kim et al. NATURE METHODS
- The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy
- (2018) Jordan A. Krall et al. Science Translational Medicine
- BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression
- (2018) Fang Wei et al. Cell Death & Disease
- Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma
- (2018) Yi He et al. Cell Death & Disease
- Identification of genomic alterations in nasopharyngeal carcinoma and nasopharyngeal carcinoma-derived Epstein–Barr virus by whole-genome sequencing
- (2018) Chaofeng Tu et al. CARCINOGENESIS
- The emerging role of Epstein-Barr virus encoded microRNAs in nasopharyngeal carcinoma
- (2018) Chunmei Fan et al. Journal of Cancer
- Effects of tumor metabolic microenvironment on regulatory T cells
- (2018) Yi-an Wang et al. Molecular Cancer
- Actively personalized vaccination trial for newly diagnosed glioblastoma
- (2018) Norbert Hilf et al. NATURE
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
- (2018) Derin B. Keskin et al. NATURE
- Noncoding regions are the main source of targetable tumor-specific antigens
- (2018) Céline M. Laumont et al. Science Translational Medicine
- Application of atomic force microscopy in cancer research
- (2018) Xiangying Deng et al. JOURNAL OF NANOBIOTECHNOLOGY
- A Case for a Human Immuno-Peptidome Project Consortium
- (2017) Etienne Caron et al. IMMUNITY
- Identification of B and T cell epitope based peptide vaccine from IGF-1 receptor in breast cancer
- (2017) Manijeh Mahdavi et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Dendritic cell based vaccination strategy: an evolving paradigm
- (2017) Anna C. Filley et al. JOURNAL OF NEURO-ONCOLOGY
- A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence-guided surgery in newly diagnosed glioblastoma patients
- (2017) Susana Inogés et al. Journal of Translational Medicine
- Genome-Wide Analysis of 18 Epstein-Barr Viruses Isolated from Primary Nasopharyngeal Carcinoma Biopsy Specimens
- (2017) Chaofeng Tu et al. JOURNAL OF VIROLOGY
- Role of long non-coding RNAs in glucose metabolism in cancer
- (2017) Chunmei Fan et al. Molecular Cancer
- Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
- (2017) Ugur Sahin et al. NATURE
- Elements of cancer immunity and the cancer–immune set point
- (2017) Daniel S. Chen et al. NATURE
- An immunogenic personal neoantigen vaccine for patients with melanoma
- (2017) Patrick A. Ott et al. NATURE
- The Antigenicity of the Tumor Cell — Context Matters
- (2017) Vessela N. Kristensen NEW ENGLAND JOURNAL OF MEDICINE
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Trend analysis of cancer incidence and mortality in China
- (2017) Fang Wei et al. Science China-Life Sciences
- Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor
- (2017) Teresa Lozano et al. Oncotarget
- Role of tumor microenvironment in tumorigenesis
- (2017) Maonan Wang et al. Journal of Cancer
- Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer
- (2017) Julia Tchou et al. Cancer Immunology Research
- Vaccination with High-Affinity Epitopes Impairs Antitumor Efficacy by Increasing PD-1 Expression on CD8 + T Cells
- (2017) Christopher D. Zahm et al. Cancer Immunology Research
- The Potential of Donor T-Cell Repertoires in Neoantigen-Targeted Cancer Immunotherapy
- (2017) Terhi Karpanen et al. Frontiers in Immunology
- Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines
- (2016) G. Bakdash et al. CANCER RESEARCH
- Neoantigen: A Long March toward Cancer Immunotherapy
- (2016) Y. Liu CLINICAL CANCER RESEARCH
- Immune checkpoint blockade in lymphoid malignancies
- (2016) Gita Thanarajasingam et al. FEBS Journal
- Ionic immune suppression within the tumour microenvironment limits T cell effector function
- (2016) Robert Eil et al. NATURE
- T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer
- (2016) Eric Tran et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase 1 clinical trial demonstrated that MUC1 positive metastatic seminal vesicle cancer can be effectively eradicated by modified Anti-MUC1 chimeric antigen receptor transduced T cells
- (2016) Fengtao You et al. Science China-Life Sciences
- pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens
- (2016) Jasreet Hundal et al. Genome Medicine
- Gapped sequence alignment using artificial neural networks: application to the MHC class I system
- (2015) Massimo Andreatta et al. BIOINFORMATICS
- Targeted therapy in cancer
- (2015) Apostolia-Maria Tsimberidou CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
- (2015) Michael S. Rooney et al. CELL
- A Randomized Phase II Trial of Sipuleucel-T with Concurrent versus Sequential Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer
- (2015) E. J. Small et al. CLINICAL CANCER RESEARCH
- Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation
- (2015) M. Leisegang et al. CLINICAL CANCER RESEARCH
- Cancer Immunotherapy: A Future Paradigm Shift in the Treatment of Non-Small Cell Lung Cancer
- (2015) V. K. Anagnostou et al. CLINICAL CANCER RESEARCH
- TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity
- (2015) Jennifer D Stone et al. CURRENT OPINION IN IMMUNOLOGY
- Therapeutic cancer vaccines
- (2015) Cornelis J.M. Melief et al. JOURNAL OF CLINICAL INVESTIGATION
- Anti–PD-1/PD-L1 therapy of human cancer: past, present, and future
- (2015) Lieping Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- PD-1/PD-L1 Blockade Together With Vaccine Therapy Facilitates Effector T-Cell Infiltration Into Pancreatic Tumors
- (2015) Kevin C. Soares et al. JOURNAL OF IMMUNOTHERAPY
- Combination cancer immunotherapies tailored to the tumour microenvironment
- (2015) Mark J. Smyth et al. Nature Reviews Clinical Oncology
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells
- (2015) B. M. Carreno et al. SCIENCE
- Clonal status of actionable driver events and the timing of mutational processes in cancer evolution
- (2015) Nicholas McGranahan et al. Science Translational Medicine
- Cancer vaccines
- (2015) L. H. Butterfield BMJ-British Medical Journal
- Cancer vaccines
- (2015) L. H. Butterfield BMJ-British Medical Journal
- PD-1 or PD-L1 Blockade Restores Antitumor Efficacy Following SSX2 Epitope-Modified DNA Vaccine Immunization
- (2015) B. T. Rekoske et al. Cancer Immunology Research
- Neoepitopes of Cancers: Looking Back, Looking Ahead
- (2015) P. K. Srivastava Cancer Immunology Research
- Vaccines Combined with Immune Checkpoint Antibodies Promote Cytotoxic T-cell Activity and Tumor Eradication
- (2015) O. A. Ali et al. Cancer Immunology Research
- OptiType: precision HLA typing from next-generation sequencing data
- (2014) András Szolek et al. BIOINFORMATICS
- Accumulation of Memory Precursor CD8 T Cells in Regressing Tumors following Combination Therapy with Vaccine and Anti-PD-1 Antibody
- (2014) L. Karyampudi et al. CANCER RESEARCH
- Personalized Medicine for Patients with Advanced Cancer in the Phase I Program at MD Anderson: Validation and Landmark Analyses
- (2014) A.-M. Tsimberidou et al. CLINICAL CANCER RESEARCH
- Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
- (2014) Matthew M. Gubin et al. NATURE
- Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
- (2014) Mahesh Yadav et al. NATURE
- A vaccine targeting mutant IDH1 induces antitumour immunity
- (2014) Theresa Schumacher et al. NATURE
- Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
- (2014) Marco Gerlinger et al. NATURE GENETICS
- High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
- (2014) Carsten Linnemann et al. NATURE MEDICINE
- Therapeutic vaccines for cancer: an overview of clinical trials
- (2014) Ignacio Melero et al. Nature Reviews Clinical Oncology
- Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
- (2014) Alexandra Snyder et al. NEW ENGLAND JOURNAL OF MEDICINE
- COSMIC: exploring the world's knowledge of somatic mutations in human cancer
- (2014) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer
- (2014) E. Tran et al. SCIENCE
- Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
- (2014) E. C. de Bruin et al. SCIENCE
- High sensitivity of cancer exome-based CD8 T cell neo-antigen identification
- (2014) Marit M van Buuren et al. OncoImmunology
- Pathways of Antigen Processing
- (2013) Janice S. Blum et al. Annual Review of Immunology
- A comparative analysis of algorithms for somatic SNV detection in cancer
- (2013) Nicola D. Roberts et al. BIOINFORMATICS
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
- (2013) Paul F Robbins et al. NATURE MEDICINE
- Nivolumab plus Ipilimumab in Advanced Melanoma
- (2013) Jedd D. Wolchok et al. NEW ENGLAND JOURNAL OF MEDICINE
- ATHLATES: accurate typing of human leukocyte antigen through exome sequencing
- (2013) Chang Liu et al. NUCLEIC ACIDS RESEARCH
- Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells
- (2013) S. Spranger et al. Science Translational Medicine
- Computational optimisation of targeted DNA sequencing for cancer detection
- (2013) Pierre Martinez et al. Scientific Reports
- Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs
- (2012) Christopher T. Saunders et al. BIOINFORMATICS
- Exploiting the Mutanome for Tumor Vaccination
- (2012) J. C. Castle et al. CANCER RESEARCH
- Personalized Medicine in a Phase I Clinical Trials Program: The MD Anderson Cancer Center Initiative
- (2012) A.-M. Tsimberidou et al. CLINICAL CANCER RESEARCH
- Different affinity windows for virus and cancer-specific T-cell receptors: Implications for therapeutic strategies
- (2012) Milos Aleksic et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
- (2012) D. C. Koboldt et al. GENOME RESEARCH
- Intravenous genetic mesothelin vaccine based on human adenovirus 40 inhibits growth and metastasis of pancreatic cancer
- (2012) Satoshi Yamasaki et al. INTERNATIONAL JOURNAL OF CANCER
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape
- (2012) J. M. Taube et al. Science Translational Medicine
- T-Cell Tolerance: Central and Peripheral
- (2012) Y. Xing et al. Cold Spring Harbor Perspectives in Biology
- Derivation of HLA types from shotgun sequence datasets
- (2012) René L Warren et al. Genome Medicine
- Targeting the tumor mutanome for personalized vaccination therapy
- (2012) Sebastian Kreiter et al. OncoImmunology
- Cancer Genome Sequencing and Its Implications for Personalized Cancer Vaccines
- (2011) Lijin Li et al. Cancers
- Intranodal Vaccination with Naked Antigen-Encoding RNA Elicits Potent Prophylactic and Therapeutic Antitumoral Immunity
- (2010) S. Kreiter et al. CANCER RESEARCH
- Selective Depletion of Foxp3+ Regulatory T Cells Improves Effective Therapeutic Vaccination against Established Melanoma
- (2010) K. Klages et al. CANCER RESEARCH
- MHC Class II epitope predictive algorithms
- (2010) Morten Nielsen et al. IMMUNOLOGY
- A Peptide Inhibitor of FOXP3 Impairs Regulatory T Cell Activity and Improves Vaccine Efficacy in Mice
- (2010) N. Casares et al. JOURNAL OF IMMUNOLOGY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
- (2010) M. A. Curran et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Derivation of an amino acid similarity matrix for peptide:MHC binding and its application as a Bayesian prior
- (2009) Yohan Kim et al. BMC BIOINFORMATICS
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