Identification of a mitofusin specificity region that confers unique activities to Mfn1 and Mfn2

A catalytic domain variant of mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion

(2019) Emily A. Engelhart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion

(2018) Liming Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion

(2018) Liming Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evolving Concepts of Mitochondrial Dynamics

(2018) Gerald W. Dorn   Annual Review of Physiology

A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space

(2017) Sevan Mattie et al.   JOURNAL OF CELL BIOLOGY

Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria

(2017) Janos Steffen et al.   MOLECULAR BIOLOGY OF THE CELL

MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion

(2017) Yu-Lu Cao et al.   NATURE

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

(2016) Lena Pernas et al.   Annual Review of Physiology

Membrane fission by dynamin: what we know and what we need to know

(2016) Bruno Antonny et al.   EMBO JOURNAL

Structures of human mitofusin 1 provide insight into mitochondrial tethering

(2016) Yuanbo Qi et al.   JOURNAL OF CELL BIOLOGY

Correcting mitochondrial fusion by manipulating mitofusin conformations

(2016) Antonietta Franco et al.   NATURE

Mitochondrial dynamics and inherited peripheral nerve diseases

(2015) Davide Pareyson et al.   NEUROSCIENCE LETTERS

Mitochondrial form and function

(2014) Jonathan R. Friedman et al.   NATURE

Disturbed mitochondrial dynamics and neurodegenerative disorders

(2014) Florence Burté et al.   Nature Reviews Neurology

GTP-Dependent Membrane Fusion

(2013) James A. McNew et al.   Annual Review of Cell and Developmental Biology

Mitochondrial dynamics in neurodegeneration

(2012) Kie Itoh et al.   TRENDS IN CELL BIOLOGY

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes

(2011) Suzanne Hoppins et al.   MOLECULAR CELL

Structure of a Bacterial Dynamin-like Protein Lipid Tube Provides a Mechanism For Assembly and Membrane Curving

(2009) Harry H. Low et al.   CELL

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

(2009) Rachel M. DeVay et al.   JOURNAL OF CELL BIOLOGY