Tissue, urine and blood metabolite signatures of chronic kidney disease in the 5/6 nephrectomy rat model

Proximal Tubular Secretory Clearance

(2018) Ke Wang et al.   Clinical Journal of the American Society of Nephrology

Serum metabolites are associated with all-cause mortality in chronic kidney disease

(2018) Jiun-Ruey Hu et al.   KIDNEY INTERNATIONAL

Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016

(2018) Yan Xie et al.   KIDNEY INTERNATIONAL

Acid retention with reduced glomerular filtration rate increases urine biomarkers of kidney and bone injury

(2017) Donald E. Wesson et al.   KIDNEY INTERNATIONAL

Intradialytic creatine supplementation: A scientific rationale for improving the health and quality of life of dialysis patients

(2017) Theo Wallimann et al.   MEDICAL HYPOTHESES

HMDB 4.0: the human metabolome database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Renal and Systemic Effects of Calorie Restriction in Patients With Type 2 Diabetes With Abdominal Obesity: A Randomized Controlled Trial

(2016) Piero Ruggenenti et al.   DIABETES

Metabolomic Signatures of Chronic Kidney Disease of Diverse Etiologies in the Rats and Humans

(2016) Zhi-Hao Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Untargeted plasma and tissue metabolomics in rats with chronic kidney disease given AST-120

(2016) Thomas J. Velenosi et al.   Scientific Reports

Identification of biomarkers for development of end-stage kidney disease in chronic kidney disease by metabolomic profiling

(2016) Tomonori Kimura et al.   Scientific Reports

Creatine biosynthesis and transport in health and disease

(2015) Marie Joncquel-Chevalier Curt et al.   BIOCHIMIE

Tubular Secretion in CKD

(2015) A. M. Suchy-Dicey et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Precision High-Throughput Proton NMR Spectroscopy of Human Urine, Serum, and Plasma for Large-Scale Metabolic Phenotyping

(2014) Anthony C. Dona et al.   ANALYTICAL CHEMISTRY

1H NMR-Based Metabolite Profiling of Plasma in a Rat Model of Chronic Kidney Disease

(2014) Ju-Ae Kim et al.   PLoS One

Plasma Dimethylglycine and Risk of Incident Acute Myocardial Infarction in Patients With Stable Angina Pectoris

(2013) Gard Frodahl Tveitevåg Svingen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Metabolomics in chronic kidney disease

(2013) Ying-Yong Zhao   CLINICA CHIMICA ACTA

Uric Acid Lowering to Prevent Kidney Function Loss in Diabetes: The Preventing Early Renal Function Loss (PERL) Allopurinol Study

(2013) David M. Maahs et al.   Current Diabetes Reports

Hippurate: The Natural History of a Mammalian–Microbial Cometabolite

(2013) Hannah J. Lees et al.   JOURNAL OF PROTEOME RESEARCH

A Combined Epidemiologic and Metabolomic Approach Improves CKD Prediction

(2013) E. P. Rhee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Identification of a urine metabolomic signature in patients with advanced-stage chronic kidney disease

(2013) Maria Posada-Ayala et al.   KIDNEY INTERNATIONAL

Metabolites associate with kidney function decline and incident chronic kidney disease in the general population

(2013) Oemer-Necmi Goek et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Optimized Metabolomic Approach to Identify Uremic Solutes in Plasma of Stage 3–4 Chronic Kidney Disease Patients

(2013) Henricus A. M. Mutsaers et al.   PLoS One

Evaluation of metabolomic profiling against renal toxicity in Sprague–Dawley rats treated with melamine and cyanuric acid

(2012) Tae Hyung Kim et al.   ARCHIVES OF TOXICOLOGY

The nutritional burden of methylation reactions

(2012) Robert F. Bertolo et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Mechanisms and Treatment of CKD

(2012) P. Ruggenenti et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Normal and Pathologic Concentrations of Uremic Toxins

(2012) F. Duranton et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Metabolomic Approach to Clarifying the Effect of AST-120 on 5/6 Nephrectomized Rats by Capillary Electrophoresis with Mass Spectrometry (CE-MS)

(2012) Yasutoshi Akiyama et al.   Toxins

Creatine as an antioxidant

(2011) Piero Sestili et al.   AMINO ACIDS

1H NMR spectroscopy analysis of metabolites in the kidneys provides new insight into pathophysiological mechanisms: applications for treatment with Cordyceps sinensis

(2011) F. Zhong et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk

(2010) M. Goicoechea et al.   Clinical Journal of the American Society of Nephrology

Metabolite Profiling Identifies Markers of Uremia

(2010) E. P. Rhee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR

(2010) Sorot Phisitkul et al.   KIDNEY INTERNATIONAL

p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease

(2010) I.-W. Wu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Dialysis modality-dependent changes in serum metabolites: accumulation of inosine and hypoxanthine in patients on haemodialysis

(2010) J.-Y. Choi et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

An exploratory NMR nutri-metabonomic investigation reveals dimethyl sulfone as a dietary biomarker for onion intake

(2009) Hanne Winning et al.   ANALYST

Pattern recognition analysis for 1H NMR spectra of plasma from hemodialysis patients

(2009) Masako Fujiwara et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Folate, Cobalamin, Cysteine, Homocysteine, and Arsenic Metabolism among Children in Bangladesh

(2009) Megan N. Hall et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bicarbonate Supplementation Slows Progression of CKD and Improves Nutritional Status

(2009) I. de Brito-Ashurst et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Allantoin as a marker of oxidative stress in human erythrocytes

(2008) Roman Kand'ár et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE