Article
Chemistry, Multidisciplinary
Yawen Li, Naiyao Li, Guoping Li, Yi Qiao, Mingming Zhang, Lei Zhang, Qing-Hui Guo, Gang He
Summary: Selenoviologen-based tetracationic cyclophanes with rigid electron-deficient cavities were synthesized through SN2 reactions. These cyclophanes exhibit good redox properties, narrow energy gaps, and strong absorption in the visible range. They were successfully applied to electrochromic devices and visible-light-driven hydrogen production. Host-guest recognitions were demonstrated, and a simplified system for solar energy conversion was achieved.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Multidisciplinary Sciences
Manuel Weh, Kazutaka Shoyama, Frank Wuerthner
Summary: The discrimination of enantiomers by natural receptors is a well-established phenomenon, but the number of synthetic receptors with enantioselective molecular recognition capability is limited. In this study, a cyclophane composed of homochiral perylene bisimide (PBI) units was shown to preferentially bind [5]helicene of opposite helicity compared to the PBI units of the host. The enantio-differentiation of this molecular receptor for heterochiral guests can be utilized for the enrichment of specific bimolecular complex. The design of synthetic supramolecular receptors capable of enantioselective molecular recognition is challenging, and this study presents a novel approach using perylene bisimide-based receptors.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Guanghui Ouyang, Jessica Ruehe, Yang Zhang, Mei-Jin Lin, Minghua Liu, Frank Wuerthner
Summary: The study presents a chiral PBI hetero-cyclophane (BBI-PBI) with intramolecular energy and solvent-regulated chirality transfer from the BBI to the PBI subunit. The combination of excellent spectral overlap and spatial arrangement of BBI and PBI leads to efficient excitation energy transfer and high quantum yield PBI emission in various solvents, while chirality transfer is strongly dependent on the respective solvent. The combination of energy and chirality transfer results in bright red circularly polarized luminescence from the PBI chromophore by excitation of BBI.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
D. Zhao, Q. Jiang, Y. Jia, J. Zhou, N. Zheng, D. Hu, Y. Ma
Summary: This study demonstrates the use of phenyl lithium doping to create a suspension mixed with unsubstituted NDI, which can be drop-cast to prepare dense films for TE applications. By optimizing the doping ratio, impressive electrical conductivity and Seebeck coefficient were achieved in the TE film.
MATERIALS TODAY ENERGY
(2021)
Article
Chemistry, Multidisciplinary
Yuanjun Han, Suze Ma, Qi Zhang
Summary: In this study, the researchers conducted a genome-wide search for Xye-type triceptides and found they are likely specific to gamma-proteobacteria. They also investigated the substrate specificity and activity of the 3-CyFE enzyme PauB from Photorhabdus australis. The study revealed the order of cyclophane formation and the unsuitability of glycine for cyclophane formation.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Organic
Robindo Chatterjee, Bappaditya Goswami, Ambika Devi, Swati Rani, Manas Khatua, Subhas Samanta
Summary: Unprecedented metal-free complete o-phenylene bridged N-4-cyclophanes (M1 and M2) have been synthesized via sequential palladium-catalyzed Buchwald-Hartwig N-arylation reactions. These cyclophanes, considered as aromatic analogues of aliphatic group-spaced N-4-macrocycles, have been fully characterized using physicochemical techniques and X-ray structure determination. Their redox, spectral, and photophysical properties, determined by cyclic voltammetry, UV-vis spectro-electrochemistry, fluorescence spectral studies, and DFT calculations, indicate their potential applications.
Article
Multidisciplinary Sciences
Antonio Masone, Chiara Zucchelli, Enrico Caruso, Giada Lavigna, Hasier Erana, Gabriele Giachin, Laura Tapella, Liliana Comerio, Elena Restelli, Ilaria Raimondi, Saioa R. Elezgarai, Federica De Leo, Giacomo Quilici, Lorenzo Taiarol, Marvin Oldrati, Nuria L. Lorenzo, Sandra Garcia-Martinez, Alfredo Cagnotto, Jacopo Lucchetti, Marco Gobbi, Ilaria Vanni, Romolo Nonno, Michele A. Di Bari, Mark D. Tully, Valentina Cecatiello, Giuseppe Ciossani, Sebastiano Pasqualato, Eelco Van Anken, Mario Salmona, Joaquin Castilla, Jesus R. Requena, Stefano Banfi, Giovanna Musco, Roberto Chiesa
Summary: Prions are deadly infectious agents that can self-propagate by inducing misfolding of native prion protein. We discovered a compound called Zn(II)-BnPyP that can bind to different domains of the native prion protein, resulting in a dual anti-prion effect. Zn(II)-BnPyP destabilizes the native prion protein fold and triggers its degradation, thereby reducing the generation of disease-causing prions. This compound shows promising inhibitory effects against different prion strains in various experimental settings.
Article
Chemistry, Physical
Raman Khurana, Jyotirmayee Mohanty, Nilotpal Barooah, Achikanath C. Bhasikuttan
Summary: By utilizing supramolecular assembly, novel emissive radical anions can be generated, stabilized, and reacted in situ in aqueous medium. These complexes undergo photoinduced electron transfer to produce radical anions, which exhibit stability within cucurbituril nanocavities and can be used for the reduction of Au3+ to form stable AuNPs. This dynamic stability window allows for potential applications in controlled assembly of smart materials and radical-induced reactions.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Biochemistry & Molecular Biology
Maria Valentina Dinu, Ionel Adrian Dinu, Sina S. Saxer, Wolfgang Meier, Uwe Pieles, Nico Bruns
Summary: Enzymes are stabilized and protected by coencapsulating them with trehalose into polymersomes, maintaining their activity for extended periods of time even when exposed to high temperature. This method proves to be effective in preserving enzyme activity and demonstrating potential applications in catalysis.
Article
Chemistry, Multidisciplinary
Xiao Xiao, Ivan Kurganskii, Partha Maity, Jianzhang Zhao, Xiao Jiang, Omar F. Mohammed, Matvey Fedin
Summary: Spiro rhodamine (Rho)-naphthalenediimide (NDI) electron donor-acceptor orthogonal dyads were prepared to generate a long-lived charge separation state based on the electron spin control approach, prolonging the lifetime of the charge separation state.
Article
Biochemistry & Molecular Biology
Miroslaw Jablonski
Summary: Based on Bader's quantum theory, the presence of a bond path and bond critical point between two atoms is considered necessary and sufficient for them to be bonded. However, the existence of counterintuitive bond paths suggests that this statement may not always hold true, especially in endohedral complexes. Through experimental results, the author demonstrates that Bader's topological bond path does not always indicate stabilizing interactions.
Article
Chemistry, Multidisciplinary
Shuai Fang, Errui Li, Dingsheng Zhu, Guangcheng Wu, Qinhao Zhang, Chuhao Lin, Feihe Huang, Hao Li
Summary: The water-soluble cage containing three naphthalenediimide (NDI) units was synthesized in one pot without chromatographic purification, forming six irreversible C-N bonds simultaneously via an S(N)2 reaction. The cage can accommodate various pi-electron rich guests in water in a peripheral manner, form inclusion complexes with linear guests such as I-3(-) and I-2, and absorb vapor of I-2 in the solid state.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Organic
Zonghuan Lu, Wanqian Lv, Hongyi Liu, Yandie Liu, Shuhua Liao, Xijie Wang, Kelong Zhu
Summary: A pyrrolodithiin-derived cyclophane with an adaptive and stimuli-responsive geometry was designed and constructed. The foldable dithiin subunit enabled the cyclophane to have a compressible cavity that can transform from a hex-nut to a rectangular box upon complexing guests. The resulting pseudorotaxane complexes can be dethreaded via electrochemical oxidation, highlighting the potential applications in molecular switches and machines.
Article
Chemistry, Multidisciplinary
Frederic Aribot, Amelie Merle, Pierre Dechambenoit, Harald Bock, Albert Artigas, Nicolas Vanthuyne, Yannick Carissan, Denis Hagebaum-Reignier, Yoann Coquerel, Fabien Durola
Summary: A rigid propeller-shaped conjugated triple macrocycle has been synthesized, consisting of two stacked benzene rings and three linking [5]helicene moieties, using a glyoxylic Perkin approach. Electron delocalization analysis of this atypical aromatic molecule revealed global aromaticity, with a 78 pi-electron circuit along the edge of its triple loop, at the expense of the two 6 pi-electron circuits in the stacked benzene rings.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Physical
Laura Bancroft, Jinyuan Zhang, Samantha M. Harvey, Matthew D. Krzyaniak, Peng Zhang, Richard D. Schaller, David N. Beratan, Ryan M. Young, Michael R. Wasielewski
Summary: The study investigates the quantum coherence effects on charge transfer and spin dynamics in a system with two degenerate electron acceptors. Experimental results show differences in electron transfer rate and charge recombination rate between the two systems, indicating the impact of quantum coherence on these processes.
JOURNAL OF PHYSICAL CHEMISTRY A
(2021)
Article
Chemistry, Multidisciplinary
Yu Wang, Huang Wu, Leighton O. Jones, Martin A. Mosquera, Charlotte L. Stern, George C. Schatz, J. Fraser Stoddart
Summary: Cocrystal engineering is a popular strategy for tuning the photophysical properties of crystalline materials. This study reports a color-tunable upconversion-emission switch based on the interconversion between two cocrystals. The research provides a critical example of precise control of cocrystal-to-cocrystal transformation and offers a reference for fabricating color tunable nonlinear optical materials in the solid state.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Biochemistry & Molecular Biology
Guangcheng Wu, Tianyu Jiao, Hao Li
Summary: A bowl-shaped molecule can be formed by condensing a triscationic hexaaldehyde compound and dihydrazide linkers in water. The molecular bowl has a platform with a pi-electron deficiency and a hexagonal rim with acylhydrazone functions. In the presence of chloride counteranions, the molecular bowl undergoes dimerization through N-H···Cl hydrogen bonds, forming a cage-like dimer. The cavity of the molecular bowl can accommodate a hydrophobic guest, such as 1-adamantanecarboxylic acid, in aqueous media.
Review
Nanoscience & Nanotechnology
Hongliang Chen, Chuancheng Jia, Xin Zhu, Chen Yang, Xuefeng Guo, J. Fraser Stoddart
Summary: Developing new materials is a long-standing goal in various fields, and understanding single-molecule reactions can deepen our understanding of chemical reactions and provide new frameworks in materials science. This review focuses on state-of-the-art chemical reactions in single-molecule junctions and highlights the advantages of real-time testbeds for studying reaction dynamics, intermediates, transition states, and solvent effects. The behavior of single-molecule reactions is compared with reactions in ensemble states, and the potential of leveraging single-molecule catalysis for large-scale materials production is explored.
NATURE REVIEWS MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Taeyeon Kim, Yuanning Feng, James P. O'Connor, J. Fraser Stoddart, Ryan M. Young, Michael R. Wasielewski
Summary: Designing and controlling charge transfer pathways in organic semiconductors are crucial for solar energy applications. This study investigates the photoinduced charge transfer and relaxation dynamics in host-guest complexes, and demonstrates that the charge transfer pathway can be controlled by subtle chemical modifications of the acceptor host.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Hongliang Chen, Indranil Roy, Michele S. Myong, James S. W. Seale, Kang Cai, Yang Jiao, Wenqi Liu, Bo Song, Long Zhang, Xingang Zhao, Yuanning Feng, Fangjun Liu, Ryan M. Young, Michael R. Wasielewski, J. Fraser Stoddart
Summary: Triplet-triplet annihilation-based molecular photon upconversion (TTA-UC) was achieved by incorporating two porphyrinic sensitizers and encapsulating two perylene emitters inside a molecular container. The design of the container, with a suitable cavity size and ππ distance between the sensitizers and annihilators, allowed for efficient photon upconversion. This study provides new opportunities for addressing issues associated with supramolecular photon upconversion and has implications for biological imaging applications.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Yang Liu, Xin-Ru Guan, Duan-Chao Wang, J. Fraser Stoddart, Qing-Hui Guo
Summary: Single-crystal-to-single-crystal (SCSC) polymerization is an effective method for environmentally friendly preparation of polymer single crystals (PSCs) with high crystallinity and molecular weights. Solubility and solution processibility are major challenges for practical applications of PSCs, but this study successfully synthesized soluble and processable PSCs with rigid polycationic backbones. The resulting polymeric crystals have excellent solubility, crystallinity and rheological properties, and can be characterized using various techniques.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Editorial Material
Multidisciplinary Sciences
Huang Wu, Chun Tang, Long Zhang, J. Fraser Stoddart
NATIONAL SCIENCE REVIEW
(2023)
Article
Materials Science, Multidisciplinary
Xuan He, Wei Tao, Tao Wang, Jing-Xuan Zhang, Dengke Shen, Zhihan Zhang, Peifa Wei
Summary: By synergizing the cavities of macrocycles for dynamic complexing and the channels of frameworks for facile transit, intrinsic channels were constructed from an emissive cyclophane and precisely tunable emission in the solid state was realized through sequential guests' exchange. This strategy combines the advantages of both macrocycle and framework, achieving visualization, recyclability, and easy processability simultaneously. The present study provides an easy, efficient, and general platform for constructing dynamic optical materials.
ACS MATERIALS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Fangbai Xie, Haochuan Mao, Chenjian Lin, Yuanning Feng, J. Fraser Stoddart, Ryan M. Young, Michael R. Wasielewski
Summary: This study demonstrates that a photogenerated spin-correlated radical ion pair can be used to sense an electric field change through molecular recognition. The experiment shows that the distance between the two charges decreases when a certain molecule encapsulates one of the charges, indicating that the system can function as a quantum sensor to detect electric field changes.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Physical
Youwei Li, Mingxing Tang, Jiarong Li, Biyang Cheng, Chun Wang, Hui Dong, Dengke Shen
Summary: Gold nanoparticles capped with three types of natural cyclodextrins were successfully synthesized, allowing for precise control over their sizes ranging from 9 to 20 nm. These nanoparticles demonstrated excellent colloidal stability during long-term storage and showed remarkable tolerance to saline, acidic, and alkaline conditions. Importantly, the assembly of nanoparticles was achieved by using silica nanospheres functionalized with cinnamyl group and gold nanoparticles capped with three types of cyclodextrin, highlighting the selective formation of core-satellite superstructure based on host-guest molecular recognition on the nano-surface between different nanoparticles.
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
(2023)
Review
Chemistry, Multidisciplinary
Huangtianzhi Zhu, Liya Chen, Bin Sun, Mengbin Wang, Hao Li, J. Fraser Stoddart, Feihe Huang
Summary: Macrocyclic molecules have broad applications due to their guest binding properties. Extending host-guest chemistry from solution to the solid state enables the formation of more stable and processable complexes. Solid-state host-guest chemistry can encapsulate guests with higher affinities, which is crucial for applications in separation science and devices.
NATURE REVIEWS CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Xuan He, Wei Tao, Jing-Xuan Zhang, Tao Wang, Dengke Shen, Zhihan Zhang, Peifa Wei
Summary: By synergizing the cavities of macrocycles and the channels of frameworks, we have successfully constructed intrinsic channels with solid-state fluorescence and achieved precise tunable emission in the solid state through sequential guests' exchange. This strategy combines the advantages of both macrocycle and framework, enabling visualization, recyclability, and easy processability simultaneously. The present study provides an easy, efficient, and general platform for constructing dynamic optical materials.
ACS MATERIALS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Tao Li, Jia-Chuan Liu, En-Ping Liu, Bai-Tong Liu, Jing-Yu Wang, Pei-Yu Liao, Jian-Hua Jia, Yuanning Feng, Ming-Liang Tong
Summary: This study investigates the potential of a cocrystal incorporating TTF and TCPDA components in the field of NIR-II photothermal. Through experimental and theoretical analysis, it is found that the twisted conformation in the cocrystal and intermolecular charge transfer can achieve efficient photothermal conversion. The research results are significant for the development of high-performance organic NIR-II photothermal materials.