Microsatellite instability and immune checkpoint inhibitors: toward precision medicine against gastrointestinal and hepatobiliary cancers
出版年份 2019 全文链接
标题
Microsatellite instability and immune checkpoint inhibitors: toward precision medicine against gastrointestinal and hepatobiliary cancers
作者
关键词
Gastric cancer, Hepatocellular carcinoma, Immune checkpoint inhibitor, Microsatellite instability, Pancreatic cancer
出版物
JOURNAL OF GASTROENTEROLOGY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-09-07
DOI
10.1007/s00535-019-01620-7
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Utility of ultrasound-guided liver tumor biopsy for next generation sequencing-based clinical sequencing
- (2019) Yuji Eso et al. HEPATOLOGY RESEARCH
- Tumor mutational load predicts survival after immunotherapy across multiple cancer types
- (2019) Robert M. Samstein et al. NATURE GENETICS
- Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer
- (2019) Jorge Blando et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Guidelines Insights: Pancreatic Adenocarcinoma, Version 1.2019
- (2019) Margaret A. Tempero et al. Journal of the National Comprehensive Cancer Network
- Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis
- (2019) Soo Ki Kim et al. JOURNAL OF GASTROENTEROLOGY
- Nivolumab (NIVO) + low-dose ipilimumab (IPI) in previously treated patients (pts) with microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC): Long-term follow-up.
- (2019) Michael J. Overman et al. JOURNAL OF CLINICAL ONCOLOGY
- Evaluation of safety and tolerability of durvalumab (D) with or without tremelimumab (T) in patients (pts) with biliary tract cancer (BTC).
- (2019) Tatsuya Ioka et al. JOURNAL OF CLINICAL ONCOLOGY
- Results of KEYNOTE-240: phase 3 study of pembrolizumab (Pembro) vs best supportive care (BSC) for second line therapy in advanced hepatocellular carcinoma (HCC).
- (2019) Richard S. Finn et al. JOURNAL OF CLINICAL ONCOLOGY
- Nivolumab alone or in combination with cisplatin plus gemcitabine in Japanese patients with unresectable or recurrent biliary tract cancer: a non-randomised, multicentre, open-label, phase 1 study
- (2019) Makoto Ueno et al. Lancet Gastroenterology & Hepatology
- O-021Safety and antitumor activity of pembrolizumab in patients with advanced microsatellite instability–high (MSI-H) colorectal cancer: KEYNOTE-164
- (2018) D Le et al. ANNALS OF ONCOLOGY
- Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas
- (2018) Yang Liu et al. CANCER CELL
- Emerging Concepts for Immune Checkpoint Blockade-Based Combination Therapies
- (2018) Roberta Zappasodi et al. CANCER CELL
- Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations
- (2018) Zishuo I. Hu et al. CLINICAL CANCER RESEARCH
- Prevalence of Microsatellite Instability in Intraductal Papillary Mucinous Neoplasms of the Pancreas
- (2018) Renato M. Lupinacci et al. GASTROENTEROLOGY
- Immune checkpoint blockade for the treatment of human hepatocellular carcinoma
- (2018) Naoshi Nishida et al. HEPATOLOGY RESEARCH
- Novel approaches for molecular targeted therapy against hepatocellular carcinoma
- (2018) Yuji Eso et al. HEPATOLOGY RESEARCH
- Genetic features of multicentric/multifocal intramucosal gastric carcinoma
- (2018) Aya Mizuguchi et al. INTERNATIONAL JOURNAL OF CANCER
- Metastatic Pancreatic Cancer: ASCO Clinical Practice Guideline Update
- (2018) Davendra P.S. Sohal et al. JOURNAL OF CLINICAL ONCOLOGY
- Germline variants in pancreatic cancer patients with a personal or family history of cancer fulfilling the revised Bethesda guidelines
- (2018) Akihiro Ohmoto et al. JOURNAL OF GASTROENTEROLOGY
- Lynch Syndrome - Cancer Pathways, Heterogeneity and Immune Escape
- (2018) Sidhant Seth et al. JOURNAL OF PATHOLOGY
- Accuracy of four mononucleotide-repeat markers for the identification of DNA mismatch-repair deficiency in solid tumors
- (2018) Yuko Takehara et al. Journal of Translational Medicine
- Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial
- (2018) Andrew X Zhu et al. LANCET ONCOLOGY
- Landscape of Tumor Mutation Load, Mismatch Repair Deficiency, and PD-L1 Expression in a Large Patient Cohort of Gastrointestinal Cancers
- (2018) Mohamed E. Salem et al. MOLECULAR CANCER RESEARCH
- Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer
- (2018) Seung Tae Kim et al. NATURE MEDICINE
- ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade
- (2018) Jianfeng Shen et al. NATURE MEDICINE
- Genetic heterogeneity of primary lesion and metastasis in small intestine neuroendocrine tumors
- (2018) Dirk Walter et al. Scientific Reports
- Microsatellite instability status determined by next-generation sequencing and compared with PD-L1 and tumor mutational burden in 11,348 patients
- (2018) Ari Vanderwalde et al. Cancer Medicine
- Cancer Drugs Approved Based on Biomarkers and Not Tumor Type—FDA Approval of Pembrolizumab for Mismatch Repair-Deficient Solid Cancers
- (2018) Vinay Prasad et al. JAMA Oncology
- Large-scale analyses of tumor mutation burdens (TMBs) across various advanced gastrointestinal (GI) malignancies in the nationwide cancer genome screening project, SCRUM-Japan GI-SCREEN.
- (2018) Yoshiaki Nakamura et al. JOURNAL OF CLINICAL ONCOLOGY
- Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options
- (2018) Derya Kabacaoglu et al. Frontiers in Immunology
- Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic
- (2018) T A Chan et al. ANNALS OF ONCOLOGY
- 625PDPembrolizumab for advanced biliary adenocarcinoma: Results from the multicohort, phase II KEYNOTE-158 study
- (2018) M Ueno et al. ANNALS OF ONCOLOGY
- Nivolumab for the treatment of hepatocellular carcinoma
- (2018) Fabian Finkelmeier et al. Expert Review of Anticancer Therapy
- Next-generation sequencing-based clinical sequencing: toward precision medicine in solid tumors
- (2018) Toshifumi Wakai et al. International Journal of Clinical Oncology
- Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer
- (2018) Alicia Latham et al. JOURNAL OF CLINICAL ONCOLOGY
- Trial watch: The clinical trial landscape for PD1/PDL1 immune checkpoint inhibitors
- (2018) Jun Tang et al. NATURE REVIEWS DRUG DISCOVERY
- Systemic Therapy for Hepatocellular Carcinoma: Latest Advances
- (2018) Masatoshi Kudo Cancers
- Hypermutated tumours in the era of immunotherapy: The paradigm of personalised medicine
- (2017) Laetitia Nebot-Bral et al. EUROPEAN JOURNAL OF CANCER
- Liquid biopsies in gastrointestinal malignancies: when is the big day?
- (2017) Anthony Lopez et al. Expert Review of Anticancer Therapy
- Molecular alterations in colorectal adenomas and intramucosal adenocarcinomas defined by high-density single-nucleotide polymorphism arrays
- (2017) Makoto Eizuka et al. JOURNAL OF GASTROENTEROLOGY
- DNA mismatch repair and its many roles in eukaryotic cells
- (2017) Dekang Liu et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Tumor Mutational Burden and Response Rate to PD-1 Inhibition
- (2017) Mark Yarchoan et al. NEW ENGLAND JOURNAL OF MEDICINE
- A molecular portrait of microsatellite instability across multiple cancers
- (2017) Isidro Cortes-Ciriano et al. Nature Communications
- DNA Damage and Repair Biomarkers of Immunotherapy Response
- (2017) Kent W. Mouw et al. Cancer Discovery
- MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development
- (2016) Y. Eso et al. CANCER RESEARCH
- Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
- (2016) Pål Møller et al. GUT
- Efficacy of PD-1 blockade in tumors with MMR deficiency
- (2016) Valerie Lee et al. Immunotherapy
- Genetic basis of hepatitis virus-associated hepatocellular carcinoma: linkage between infection, inflammation, and tumorigenesis
- (2016) Haruhiko Takeda et al. JOURNAL OF GASTROENTEROLOGY
- Classification and characterization of microsatellite instability across 18 cancer types
- (2016) Ronald J Hause et al. NATURE MEDICINE
- Mismatch Repair Deficiency and Response to Immune Checkpoint Blockade
- (2016) Valerie Lee et al. ONCOLOGIST
- Repair Pathway Choices and Consequences at the Double-Strand Break
- (2016) Raphael Ceccaldi et al. TRENDS IN CELL BIOLOGY
- Microsatellite Instability Testing and Its Role in the Management of Colorectal Cancer
- (2015) Hisato Kawakami et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- The consensus molecular subtypes of colorectal cancer
- (2015) Justin Guinney et al. NATURE MEDICINE
- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
- (2015) Dung T. Le et al. NEW ENGLAND JOURNAL OF MEDICINE
- Applicability of Next Generation Sequencing Technology in Microsatellite Instability Testing
- (2015) Chun Gan et al. Genes
- Pancreatic Adenocarcinoma
- (2015) David P. Ryan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Comprehensive molecular characterization of gastric adenocarcinoma
- (2014) Adam J. Bass et al. NATURE
- The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
- (2014) Nicolas J. Llosa et al. Cancer Discovery
- Cancer Genetics and Epigenetics: Two Sides of the Same Coin?
- (2012) Jueng Soo You et al. CANCER CELL
- Inflammation-Associated Cancer Development in Digestive Organs: Mechanisms and Roles for Genetic and Epigenetic Modulation
- (2012) Tsutomu Chiba et al. GASTROENTEROLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma
- (2010) Richard E. Royal et al. JOURNAL OF IMMUNOTHERAPY
- Gemcitabine alone or in combination with cisplatin in patients with advanced or metastatic cholangiocarcinomas or other biliary tract tumours: a multicentre randomised phase II study – The UK ABC-01 Study
- (2009) J W Valle et al. BRITISH JOURNAL OF CANCER
- Common variants in mismatch repair genes and risk of colorectal cancer
- (2008) T Koessler et al. GUT
- Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1
- (2008) Marjolijn J L Ligtenberg et al. NATURE GENETICS
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