Sepsis induced cardiomyopathy: Pathophysiology and use of mechanical circulatory support for refractory shock

Sepsis remains a major cause of morbidity and mortality, and sepsis-induced cardiomyopathy (SCM) has been recognized as a relevant complication. In this article, the pathophysiology of SCM and the literature regarding the clinical care with a focus on the use of mechanical circulatory support for the rescue of patients with severe SCM are reviewed. Lastly, a pragmatic approach to the care of this complex patient population is provided using a representative case example. (C) 2019 Elsevier Inc. All rights reserved.