Chemotherapy-induced senescent cancer cells engulf other cells to enhance their survival

p53 Mediates Vast Gene Expression Changes That Contribute to Poor Chemotherapeutic Response in a Mouse Model of Breast Cancer

(2018) Crystal Tonnessen-Murray et al.   Translational Oncology

Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death

(2018) Isabelle Martins et al.   Cell Death & Disease

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer

(2018) Ilirjana Bajrami et al.   Cancer Discovery

Oncodriver inhibition and CD4+ Th1 cytokines cooperate through Stat1 activation to induce tumor senescence and apoptosis in HER2+ and triple negative breast cancer: implications for combining immune and targeted therapies

(2018) Cinthia Rosemblit et al.   Oncotarget

Differentially regulated gene expression in quiescence versus senescence and identification of ARID5A as a quiescence associated marker

(2017) Tarique Anwar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

(2017) Matthew P. Goetz et al.   JNCI-Journal of the National Cancer Institute

Entosis Is Induced by Glucose Starvation

(2017) Jens C. Hamann et al.   Cell Reports

Mitosis can drive cell cannibalism through entosis

(2017) Joanne Durgan et al.   eLife

Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

(2017) Matthew P. Goetz et al.   JNCI-Journal of the National Cancer Institute

Mechanisms and consequences of entosis

(2016) Shefali Krishna et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cancer cells enter dormancy after cannibalizing mesenchymal stem/stromal cells (MSCs)

(2016) Thomas J. Bartosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Mouse Macrophages Sense What Is Going On

(2016) Klaus Ley et al.   Frontiers in Immunology

TP53mutations are associated with higher rates of pathologic complete response to anthracycline/cyclophosphamide-based neoadjuvant chemotherapy in operable primary breast cancer

(2015) Yuxia Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Induction of entosis by epithelial cadherin expression

(2014) Qiang Sun et al.   CELL RESEARCH

Competition between human cells by entosis

(2014) Qiang Sun et al.   CELL RESEARCH

Enhancing Chemotherapy Efficacy in Pten -Deficient Prostate Tumors by Activating the Senescence-Associated Antitumor Immunity

(2014) Alberto Toso et al.   Cell Reports

Metabolic changes during cellular senescence investigated by proton NMR-spectroscopy

(2013) Claudia Gey et al.   MECHANISMS OF AGEING AND DEVELOPMENT

14-3-3σ expression is associated with poor pathological complete response to neoadjuvant chemotherapy in human breast cancers

(2012) Yukiko Nakamura et al.   BREAST CANCER RESEARCH AND TREATMENT

p53-Mediated Senescence Impairs the Apoptotic Response to Chemotherapy and Clinical Outcome in Breast Cancer

(2012) James G. Jackson et al.   CANCER CELL

Oncogene-induced senescence results in marked metabolic and bioenergetic alterations

(2012) Celia Quijano et al.   CELL CYCLE

Value of TP53 Status for Predicting Response to Neoadjuvant Chemotherapy in Breast Cancer: A Meta-Analysis

(2012) Min-Bin Chen et al.   PLoS One

Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells

(2012) J Cahu et al.   Cell Death & Disease

Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)

(2011) Laura J. Esserman et al.   BREAST CANCER RESEARCH AND TREATMENT

Drug-induced Senescence Generates Chemoresistant Stemlike Cells with Low Reactive Oxygen Species

(2011) Santhi Achuthan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells

(2011) C Canino et al.   ONCOGENE

Systemic DNA Damage Response and Metabolic Syndrome as a Premalignant State

(2010) A. Erol   CURRENT MOLECULAR MEDICINE

Features of senescence and cell death induced by doxorubicin in A549 cells: organization and level of selected cytoskeletal proteins

(2009) Anna Litwiniec et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Pharmacologic p53 Activation Blocks Cell Cycle Progression but Fails to Induce Senescence in Epithelial Cancer Cells

(2009) B. Huang et al.   MOLECULAR CANCER RESEARCH

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY