Roles of Myosin-Mediated Membrane Trafficking in TGF-β Signaling

The motor protein Myo1c regulates transforming growth factor-β-signaling and fibrosis in podocytes

(2019) Ehtesham Arif et al.   KIDNEY INTERNATIONAL

Pentachloropseudilin Inhibits Transforming Growth Factor-β (TGF-β) Activity by Accelerating Cell-Surface Type II TGF-β Receptor Turnover in Target Cells

(2018) Chih-Ling Chung et al.   CHEMBIOCHEM

Pentabromopseudilin: a myosin V inhibitor suppresses TGF-β activity by recruiting the type II TGF-β receptor to lysosomal degradation

(2018) Wang Shih-Wei et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response

(2018) D. Dvornikov et al.   Scientific Reports

Transforming Growth Factor-β Receptors and Smads: Regulatory Complexity and Functional Versatility

(2017) Erine H. Budi et al.   TRENDS IN CELL BIOLOGY

Myosin 1g Contributes to CD44 Adhesion Protein and Lipid Rafts Recycling and Controls CD44 Capping and Cell Migration in B Lymphocytes

(2017) Orestes López-Ortega et al.   Frontiers in Immunology

The Globular Tail Domain of Myosin-5a Functions as a Dimer in Regulating the Motor Activity

(2016) Wen-Bo Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholest-4-en-3-one attenuates TGF-β responsiveness by inducing TGF-β receptors degradation in Mv1Lu cells and colorectal adenocarcinoma cells

(2016) Chun-Lin Chen et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation

(2016) Jessica L. Ouderkirk-Pecone et al.   Oncotarget

CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface

(2015) Ihor Yakymovych et al.   JOURNAL OF CELL BIOLOGY

Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion

(2015) Hemma Brandstaetter et al.   Autophagy

Increased pSmad2 expression and cytoplasmic predominant presence of TGF-βRII in breast cancer tissue are associated with poor prognosis: results from the Shanghai Breast Cancer Study

(2014) Qingchao Qiu et al.   BREAST CANCER RESEARCH AND TREATMENT

Mutant p53–associated myosin-X upregulation promotes breast cancer invasion and metastasis

(2014) Antti Arjonen et al.   JOURNAL OF CLINICAL INVESTIGATION

Myosin 1g regulates cytoskeleton plasticity, cell migration, exocytosis, and endocytosis in B lymphocytes

(2013) José L. Maravillas-Montero et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

c-Cbl-Mediated Neddylation Antagonizes Ubiquitination and Degradation of the TGF-β Type II Receptor

(2013) Wei Zuo et al.   MOLECULAR CELL

PICK1 promotes caveolin-dependent degradation of TGF-β type I receptor

(2012) Bing Zhao et al.   CELL RESEARCH

Post-translational regulation of TGF-β receptor and Smad signaling

(2012) Pinglong Xu et al.   FEBS LETTERS

Complexities of TGF-β Targeted Cancer Therapy

(2012) Erin C. Connolly et al.   International Journal of Biological Sciences

Tollip, an Intracellular Trafficking Protein, Is a Novel Modulator of the Transforming Growth Factor-β Signaling Pathway

(2012) Lu Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myo1c regulates lipid raft recycling to control cell spreading, migration and Salmonella invasion

(2012) H. Brandstaetter et al.   JOURNAL OF CELL SCIENCE

Myosin 1E coordinates actin assembly and cargo trafficking during clathrin-mediated endocytosis

(2012) Jackie Cheng et al.   MOLECULAR BIOLOGY OF THE CELL

A Gene Signature for Predicting Outcome in Patients with Basal-like Breast Cancer

(2012) Robin M. Hallett et al.   Scientific Reports

The TGF-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors

(2011) Albane A. Bizet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A novel gain-of-function mutation of TGF-β receptor II promotes cancer progression via delayed receptor internalization in oral squamous cell carcinoma

(2011) Iha Park et al.   CANCER LETTERS

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

TGF-β/TGF-β receptor system and its role in physiological and pathological conditions

(2011) Juan F. Santibañez et al.   CLINICAL SCIENCE

The myosin family: unconventional roles of actin-dependent molecular motors in immune cells

(2011) José L. Maravillas-Montero et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Motor Protein Myo1c Is a Podocyte Protein That Facilitates the Transport of Slit Diaphragm Protein Neph1 to the Podocyte Membrane

(2011) E. Arif et al.   MOLECULAR AND CELLULAR BIOLOGY

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

(2010) Sonja I Buschow et al.   IMMUNOLOGY AND CELL BIOLOGY

Myosin 1G Is an Abundant Class I Myosin in Lymphocytes Whose Localization at the Plasma Membrane Depends on Its Ancient Divergent Pleckstrin Homology (PH) Domain (Myo1PH)

(2010) Genaro Patino-Lopez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type II Transforming Growth Factor-β Receptor Recycling Is Dependent upon the Clathrin Adaptor Protein Dab2

(2010) Sumedha G. Penheiter et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

The extracellular domain of the TGFβ type II receptor regulates membrane raft partitioning

(2009) Valbona Luga et al.   BIOCHEMICAL JOURNAL

Unconventional myosins acting unconventionally

(2009) Sarah Woolner et al.   TRENDS IN CELL BIOLOGY

How are the cellular functions of myosin VI regulated within the cell?

(2008) Folma Buss et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes

(2008) Andreas Linkermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Endocytic regulation of TGF-β signaling

(2008) Ye-Guang Chen   CELL RESEARCH

Rapid Recycling of β2-Adrenergic Receptors is Dependent on the Actin Cytoskeleton and Myosin Vb

(2008) Ellen E. Millman et al.   TRAFFIC

Calcium and cargoes as regulators of myosin 5a activity

(2007) James R. Sellers et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS