Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling
出版年份 2019 全文链接
标题
Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 18, Pages 4511
出版商
MDPI AG
发表日期
2019-09-12
DOI
10.3390/ijms20184511
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- (2019) Andrés J. M. Ferreri et al. BLOOD
- Targeting Tumor Vasculature with TNF Leads Effector T Cells to the Tumor and Enhances Therapeutic Efficacy of Immune Checkpoint Blockers in Combination with Adoptive Cell Therapy
- (2018) Angela Rita Elia et al. CLINICAL CANCER RESEARCH
- NGR-hTNF in combination with best investigator choice in previously treated malignant pleural mesothelioma (NGR015): a randomised, double-blind, placebo-controlled phase 3 trial
- (2018) Vanesa Gregorc et al. LANCET ONCOLOGY
- NGR‐hTNF and Doxorubicin as Second‐Line Treatment of Patients with Small Cell Lung Cancer
- (2018) Vanesa Gregorc et al. ONCOLOGIST
- The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms
- (2015) Simona Porcellini et al. OncoImmunology
- A pilot Phase I study combining peptide-based vaccination and NGR-hTNF vessel targeting therapy in metastatic melanoma
- (2014) Giorgio Parmiani et al. OncoImmunology
- Peptide-Mediated Targeting of Cytokines to Tumor Vasculature: The NGR-hTNF Example
- (2013) Angelo Corti et al. BIODRUGS
- NGR-TNF, a novel vascular-targeting agent, does not induce cytokine recruitment of proangiogenic bone marrow-derived cells
- (2013) P Di Matteo et al. BRITISH JOURNAL OF CANCER
- Tyrosine Phosphorylation of CD13 Regulates Inflammatory Cell-Cell Adhesion and Monocyte Trafficking
- (2013) J. Subramani et al. JOURNAL OF IMMUNOLOGY
- Cellular Mechanisms Controlling Caspase Activation and Function
- (2013) A. B. Parrish et al. Cold Spring Harbor Perspectives in Biology
- Targeting TNF- to Neoangiogenic Vessels Enhances Lymphocyte Infiltration in Tumors and Increases the Therapeutic Potential of Immunotherapy
- (2012) A. Calcinotto et al. JOURNAL OF IMMUNOLOGY
- Linking Crystallographic Model and Data Quality
- (2012) P. A. Karplus et al. SCIENCE
- In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death and induction of FLIP by NF-κB is required to prevent it
- (2011) D M Moujalled et al. CELL DEATH AND DIFFERENTIATION
- Enhanced Expression of CD13 in Vessels of Inflammatory and Neoplastic Tissues
- (2011) Paola Di Matteo et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Targeted Drug Delivery and Penetration Into Solid Tumors
- (2011) Angelo Corti et al. MEDICINAL RESEARCH REVIEWS
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- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- 2D TR-NOESY Experiments Interrogate and Rank Ligand-Receptor Interactions in Living Human Cancer Cells
- (2010) Silvia Mari et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2010) Flavio Curnis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Erkki Ruoslahti et al. JOURNAL OF CELL BIOLOGY
- Unraveling the Binding Mechanism of Trivalent Tumor Necrosis Factor Ligands and Their Receptors
- (2010) Carlos R. Reis et al. MOLECULAR & CELLULAR PROTEOMICS
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling
- (2009) Zhaoyu Jin et al. CELL
- The life of a cell: apoptosis regulation by the PI3K/PKB pathway
- (2008) Vincent Duronio BIOCHEMICAL JOURNAL
- TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype
- (2008) R. C. A. Sainson et al. BLOOD
- Isoaspartate-Glycine-Arginine: A New Tumor Vasculature-Targeting Motif
- (2008) F. Curnis et al. CANCER RESEARCH
- JNK signaling in apoptosis
- (2008) D N Dhanasekaran et al. ONCOGENE
- The moonlighting enzyme CD13: old and new functions to target
- (2008) Paola Mina-Osorio TRENDS IN MOLECULAR MEDICINE
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