Activation of Alpha-7 Nicotinic Acetylcholine Receptors (α7nAchR) Promotes the Protective Autophagy in LPS-Induced Acute Lung Injury (ALI) In Vitro and In Vivo

MicroRNA-29c Increases the Chemosensitivity of Pancreatic Cancer Cells by Inhibiting USP22 Mediated Autophagy

(2018) Limin Huang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Activation of Central Alpha 7 Nicotinic Acetylcholine Receptor Reverses Suppressed Immune Function of T Lymphocytes and Protects Against Sepsis Lethality

(2018) Chao Ren et al.   International Journal of Biological Sciences

Till Death Do Us Part: The Marriage of Autophagy and Apoptosis

(2018) Katrina F. Cooper   Oxidative Medicine and Cellular Longevity

Lipopolysaccharide-Induced Dephosphorylation of AMPK-Activated Protein Kinase Potentiates Inflammatory Injury via Repression of ULK1-Dependent Autophagy

(2018) Kerui Fan et al.   Frontiers in Immunology

Autophagy: A Potential Therapeutic Target for Reversing Sepsis-Induced Immunosuppression

(2017) Chao Ren et al.   Frontiers in Immunology

Activation of MTOR in pulmonary epithelium promotes LPS-induced acute lung injury

(2016) Yue Hu et al.   Autophagy

Sinomenine Hydrochloride Protects against Polymicrobial Sepsis via Autophagy

(2015) Yu Jiang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Acute Respiratory Distress Syndrome: From Mechanism to Translation

(2015) SeungHye Han et al.   JOURNAL OF IMMUNOLOGY

Activation of α7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: Implications for Parkinson's disease

(2015) Yuan Liu et al.   NEUROPHARMACOLOGY

Neuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor (α7nAchR)-mediated autophagy flux

(2015) Jae-Kyo Jeong et al.   Oncotarget

Nicotine Elevated Intracellular Ca2+in Rat Airway Smooth Muscle Cells via Activating and Up-Regulating a7-Nicotinic Acetylcholine Receptor

(2014) Yongliang Jiang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review

(2014) Imen Belhadj Slimen et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

AQW051, a novel and selective nicotinic acetylcholine receptor α7 partial agonist, reduces l-Dopa-induced dyskinesias and extends the duration of l-Dopa effects in parkinsonian monkeys

(2014) Thérèse Di Paolo et al.   PARKINSONISM & RELATED DISORDERS

T-Cell Autophagy Deficiency Increases Mortality and Suppresses Immune Responses after Sepsis

(2014) Chih-Wen Lin et al.   PLoS One

Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury

(2013) Yu-Ting Yen et al.   SURGERY

Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: Impact on the aging process

(2012) Antero Salminen et al.   AGEING RESEARCH REVIEWS

Lc3 Over-Expression Improves Survival and Attenuates Lung Injury Through Increasing Autophagosomal Clearance in Septic Mice

(2012) Steven Lo et al.   ANNALS OF SURGERY

Role of Oxidative Stress and Molecular Changes in Liver Fibrosis: A Review

(2012) V. Sanchez-Valle et al.   CURRENT MEDICINAL CHEMISTRY

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

(2012) Julia Romanov et al.   EMBO JOURNAL

Central roles of apoptotic proteins in mitochondrial function

(2012) S M Kilbride et al.   ONCOGENE

Nicotinic Acetylcholine Receptor Agonists Attenuate Septic Acute Kidney Injury in Mice by Suppressing Inflammation and Proteasome Activity

(2012) Prodyot K. Chatterjee et al.   PLoS One

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

(2012) Jean-Paul Decuypere et al.   Cells

Suppression of NF-κB pathway by crocetin contributes to attenuation of lipopolysaccharide-induced acute lung injury in mice

(2011) Ruhui Yang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

(2011) James Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis

(2010) Yushan Zhu et al.   Protein & Cell

Participation of Mammalian Target of Rapamycin Complex 1 in Toll-Like Receptor 2– and 4–Induced Neutrophil Activation and Acute Lung Injury

(2009) Emmanuel Lorne et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cognitive Improvement by Activation of α7 Nicotinic Acetylcholine Receptors: From Animal Models to Human Pathophysiology

(2009) Morten Thomsen et al.   CURRENT PHARMACEUTICAL DESIGN

Allergen-induced asthma in C57Bl/6 mice: Hyper-responsiveness, inflammation and remodelling

(2009) Valentina Pinelli et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Has Mortality from Acute Respiratory Distress Syndrome Decreased over Time?

(2008) Jason Phua et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Antioxidant treatment reverses mitochondrial dysfunction in a sepsis animal model

(2008) Paula H. Zapelini et al.   MITOCHONDRION

The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation

(2007) W J Jonge et al.   BRITISH JOURNAL OF PHARMACOLOGY