期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 25, 期 10, 页码 2193-2198出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2015.03.058
关键词
Psidium guajava; Benzophenone glycosides; Polyphenols; Cytotoxic activities; Antioxidant activities
资金
- National Natural Science Foundation of China [81073154, 81374061]
- Program for Innovative Research Team of the Ministry of Education
- Program for Liaoning Innovative Research Team in University
Psidium guajava (Myrtaceae) is an evergreen shrub growing extensively throughout the tropical and subtropical areas. Four new compounds, guavinoside C, D, E and F (1-3, 10) were isolated from the leaves of Psidium guajava, along with six known ones (4-9). Their structures were elucidated by spectroscopic analysis. Compounds 1, 4 and 10 showed significant cytotoxic activities on HeLa, SGC-7901 and A549 cell lines, respectively. Compounds 1 and 4-10 showed antioxidant activities in DPPH, ABTS and FRAP assays, and five of them (1, 4-6, 10) exhibited stronger activities than that of vitamin C. (C) 2015 Elsevier Ltd. All rights reserved.
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