Devimistat in combination with high dose cytarabine and mitoxantrone compared with high dose cytarabine and mitoxantrone in older patients with relapsed/refractory acute myeloid leukemia: ARMADA 2000 Phase III study

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A Phase I Study of CPI-613 in Combination with High-Dose Cytarabine and Mitoxantrone for Relapsed or Refractory Acute Myeloid Leukemia

(2018) Timothy S. Pardee et al.   CLINICAL CANCER RESEARCH

Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial

(2018) Jorge Cortes et al.   LANCET ONCOLOGY

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML

(2018) Courtney D. DiNardo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

(2017) Thomas Farge et al.   Cancer Discovery

Changes in cytogenetics and molecular genetics in acute myeloid leukemia from childhood to adult age groups

(2016) Ursula Creutzig et al.   CANCER

Genetic alterations and their clinical implications in older patients with acute myeloid leukemia

(2016) C-H Tsai et al.   LEUKEMIA

Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health

(2016) Daniel J. Tyrrell et al.   Redox Biology

Blood-cell bioenergetics are associated with physical function and inflammation in overweight/obese older adults

(2015) Daniel J. Tyrrell et al.   EXPERIMENTAL GERONTOLOGY

Treatment, trial participation and survival in adult acute myeloid leukemia: a population-based study in the Netherlands, 1989–2012

(2015) A G Dinmohamed et al.   LEUKEMIA

High dose cytarabine, mitoxantrone and l-asparaginase (HAMA) salvage for relapsed or refractory acute myeloid leukemia (AML) in the elderly

(2015) Tamjeed Ahmed et al.   LEUKEMIA RESEARCH

A Phase I Study of the First-in-Class Antimitochondrial Metabolism Agent, CPI-613, in Patients with Advanced Hematologic Malignancies

(2014) T. S. Pardee et al.   CLINICAL CANCER RESEARCH

Respirometric Profiling of Muscle Mitochondria and Blood Cells Are Associated With Differences in Gait Speed Among Community-Dwelling Older Adults

(2014) Daniel J. Tyrrell et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Lipoic acid and lipoic acid analogs in cancer metabolism and chemotherapy

(2014) Paul M Bingham et al.   Expert Review of Clinical Pharmacology

Outcome of older patients with acute myeloid leukemia in first relapse

(2013) Clémentine Sarkozy et al.   AMERICAN JOURNAL OF HEMATOLOGY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Molecular prognostic factors in cytogenetically normal acute myeloid leukemia

(2012) Alison Walker et al.   Expert Review of Hematology

Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo

(2011) Zuzana Zachar et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

(2009) H. Dohner et al.   BLOOD

The Warburg Effect in Leukemia-Stroma Cocultures Is Mediated by Mitochondrial Uncoupling Associated with Uncoupling Protein 2 Activation

(2008) I. Samudio et al.   CANCER RESEARCH

Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia

(2008) Richard F. Schlenk et al.   NEW ENGLAND JOURNAL OF MEDICINE