Article
Food Science & Technology
Jesus M. Gonzalez-Jartin, Vanesa Ferreiroa, Ines Rodriguez-Canas, Amparo Alfonso, Maria J. Sainz, Olga Aguin, Mercedes R. Vieytes, Ana Gomes, Isabel Ramos, Luis M. Botana
Summary: Maize and grass silages are important for ruminant livestock, but the presence of fungi and mycotoxins can impact the quality of silage and subsequently, milk. This study in Portugal found common fungal species and analyzed their mycotoxin profiles. Fusarium mycotoxins were detected at low levels, while Penicillium and Aspergillus toxins were less prevalent in the silages studied.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2022)
Article
Chemistry, Applied
Jesus M. Gonzalez-Jartin, Ines Rodriguez-Canas, Amparo Alfonso, Maria J. Sainz, Mercedes R. Vieytes, Ana Gomes, Isabel Ramos, Luis M. Botana
Summary: A simple method for quantifying 40 mycotoxins in milk was developed using QuEChERS extraction and UHPLC-MS/MS detection, achieving low LOQs, high recoveries, and acceptable performance characteristics in line with European regulations. The method successfully quantified mycotoxins in raw milk, highlighting the high occurrence of beauvericin and enniatins in small amounts.
Article
Agriculture, Multidisciplinary
Karl Speer, Norman Tanner, Isabelle Koelling-Speer, Anke Rohleder, Linda Zeippert, Nicole Beitlich, Birgit Lichtenberg-Kraag
Summary: Identification of single-flower honey relies on the method of melissopalynology, which uses pollen carried by forager bees in floral nectar for authentication. Lumichrome is a suitable marker substance for cornflower honey, along with other nonvolatile and volatile compounds for specific differentiation.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Food Science & Technology
Fan Liu, Jan van der Molen, Folkert Kuipers, Sander S. van Leeuwen
Summary: Human milk is the best food for infants, while infant formulas are appropriate substitutes. This study analyzed the concentrations of bioactive components in different infant formulas available on the Dutch market and found that they were lower than in human milk.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Juliana A. Barreto Peixoto, Gerardo Alvarez-Rivera, Rita C. Alves, Anabela S. G. Costa, Susana Machado, Alejandro Cifuentes, Elena Ibanez, M. Beatriz P. P. Oliveira
Summary: The study found that rosemary infusions are rich in various phenolic compounds and free amino acids, exhibiting strong antioxidant potential and providing the body with necessary antioxidants. Consuming rosemary infusions helps maintain the body's antioxidant status and prevent oxidative stress-related diseases.
Article
Agriculture, Dairy & Animal Science
Jesus M. Gonzalez-Jartin, Amparo Alfonso, Maria J. Sainz, Mercedes R. Vieytes, Luis M. Botana
Summary: A new method for multi-mycotoxin analysis was developed, based on QuEChERS extraction and UHPLC-MS/MS detection, with high recoveries and low LOQs. The study also discovered a new physical method using glass spheres to remove mycotoxins from raw materials and feedstuffs, showing a removal rate of up to 28%.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Antia Lestido-Cardama, Raquel Sendon, Juana Bustos, M. Isabel Santillana, Perfecto Paseiro Losada, Ana Rodriguez Bernaldo de Quiros
Summary: The study found that exposure to compounds from epoxy resin coatings through the consumption of canned food was low and below the established tolerable daily intake levels. A multiresidue method was developed based on HPLC-FLD and confirmed using LC-MS/MS to assess the migration of coating components into food items.
FOOD PACKAGING AND SHELF LIFE
(2021)
Article
Food Science & Technology
Thanapoom Maneeboon, Chananya Chuaysrinule, Warapa Mahakarnchanakul
Summary: Dispersive liquid-liquid microextraction was optimized and successfully applied for the simultaneous extraction and quantification of aflatoxins from powdered senna leaves and pods. The optimized method showed good efficiency and accuracy, with recoveries, RSD values, and limits of detection and quantification within acceptable ranges. This method provides a reliable approach for the analysis of aflatoxins in dried senna leaves and pods.
Article
Chemistry, Analytical
Marta Leite, Andreia Freitas, Jorge Barbosa, Fernando Ramos
Summary: The study aimed to develop a standardized methodology for extracting and detecting 22 mycotoxins in maize value chains. The validated method provided a valuable control tool for mycotoxin monitoring in multi-matrix and multi-analyte approaches.
Article
Chemistry, Applied
Marco Kraemer, Hildburg Fry, Oliver Kappenstein
Summary: Two methods for urea determination in compound feed were developed and validated, using LC-MS/MS and HPLC-FLD, and compared with a commercial enzyme kit. The newly developed methods were found to be less time-consuming in sample preparation and more stable regarding matrix effects.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2021)
Article
Food Science & Technology
Rumbidzai Changwa, Marthe De Boevre, Sarah De Saeger, Patrick Berka Njobeh
Summary: The study focused on mycotoxin contamination in feed samples from smallholder dairy establishments in South Africa, finding high levels of contamination with deoxynivalenol, sterigmatocystin, alternariol, and enniatin B. Some samples exceeded local and European regulatory limits for deoxynivalenol, aflatoxins, and zearalenone. Commercial feed showed higher contamination of certain mycotoxins compared to forages, with significant regional differences in contamination levels. Spearman correlations suggested relationships between certain mycotoxins in the samples.
Article
Agriculture, Multidisciplinary
Wenbi Guan, Yingxin You, Jialing Li, Jiaying Hong, Haiying Wu, Yanna Rao
Summary: This study is the first to report on the contamination of penicillic acid (PA) in various fruits in China. Results showed that orange/mandarin, grape, and kiwi are more favorable matrices for Aspergillus spp. and Penicillium spp. to produce PA, while peach and apple have lower incidence. The established method is essential for continuous monitoring of PA to reduce health risks for Chinese consumers.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Biochemistry & Molecular Biology
Gabriel Miguez-Suarez, Alejandra Cardelle-Cobas, Laura Sinisterra-Loaiza, Beatriz Vazquez, Alberto Cepeda, Carolina Nebot
Summary: The use of veterinary drugs in animal production is a common practice to ensure animal and human health. However, residues of these drugs could be found in animal food products, as well as in the environment, exposing humans to these substances. This study developed a multiclass method to analyze various pharmaceuticals in human feces, revealing the involuntary exposure of human gut microbiota to active substances such as pharmaceuticals.
Article
Chemistry, Applied
Ines Rodriguez-Canas, Jesus M. Gonzalez-Jartin, Amparo Alfonsoa, Rebeca Alvarino, Mercedes R. Vieytes, Luis M. Botana
Summary: Plant-based beverages have become popular in recent years due to environmental and ethical concerns, as well as milk intolerances and allergies. However, the raw materials used to make these beverages are susceptible to mycotoxin contamination. Researchers have developed a new method for analyzing mycotoxins in oat, rice, soy, and almond beverages, and found that several types of mycotoxins are present in these products.
Article
Food Science & Technology
Yongbo Li, Guofu Qin, Fengrui He, Keting Zou, Bei Zuo, Ruixiao Liu, Wei Zhang, Bixia Yang, Guipeng Zhao, Guangfeng Jia
Summary: The study investigated multi-pesticide residues in highly consumed edible fungi in China's western regions. Findings revealed the presence of primary pesticides such as carbendazim and acephate, but overall the safety status of edible fungi is deemed acceptable.
Review
Biochemistry & Molecular Biology
Luca Sforzini, Courtney Worrell, Melisa Kose, Ian M. Anderson, Bruno Aouizerate, Volker Arolt, Michael Bauer, Bernhard T. Baune, Pierre Blier, Anthony J. Cleare, Philip J. Cowen, Timothy G. Dinan, Andrea Fagiolini, I. Nicol Ferrier, Ulrich Hegerl, Andrew D. Krystal, Marion Leboyer, R. Hamish McAllister-Williams, Roger S. McIntyre, Andreas Meyer-Lindenberg, Andrew H. Miller, Charles B. Nemeroff, Claus Normann, David Nutt, Stefano Pallanti, Luca Pani, Brenda W. J. H. Penninx, Alan F. Schatzberg, Richard C. Shelton, Lakshmi N. Yatham, Allan H. Young, Roland Zahn, Georgios Aislaitner, Florence Butlen-Ducuing, Christine Fletcher, Marion Haberkamp, Thomas Laughren, Fanni-Laura Mantyla, Koen Schruers, Andrew Thomson, Gara Arteaga-Henriquez, Francesco Benedetti, Lucinda Cash-Gibson, Woo Ri Chae, Heidi De Smedt, Stefan M. Gold, Witte J. G. Hoogendijk, Valeria Jordan Mondragon, Eduard Maron, Jadwiga Martynowicz, Elisa Melloni, Christian Otte, Gabriela Perez-Fuentes, Sara Poletti, Mark E. Schmidt, Edwin van de Ketterij, Katherine Woo, Yanina Flossbach, J. Antoni Ramos-Quiroga, Adam J. Savitz, Carmine M. Pariante
Summary: The document discusses the criteria for treatment-resistant depression (TRD) and partially responsive depression (PRD) as subtypes of major depressive disorder (MDD) which are not clearly defined, using a Delphi-method-based consensus approach. It reviews literature and gathers international experts to evaluate controversies and provide recommendations on designing clinical trials and guiding research. It aims to support the design of a protocol for platform trials of new medications for TRD/PRD as part of the EUropean Patient-cEntric clinicAl tRial pLatforms, Innovative Medicines Initiative (EU-PEARL, IMI) MDD project.
MOLECULAR PSYCHIATRY
(2022)
Article
Psychology, Clinical
Cristina Varo, Silvia Amoretti, Giulio Sparacino, Esther Jimenez, Brisa Sole, Caterina del Mar Bonnin, Laura Montejo, Maria Serra, Carla Torrent, Estela Salagre, Antoni Benabarre, Pilar Salgado-Pineda, Irene Montoro Salvatierra, Pilar A. Saiz, Maria Paz Garcia-Portilla, Vanessa Sanchez-Gistau, Edith Pomarol-Clotet, Josep Antoni Ramos-Quiroga, Isabella Pacchiarotti, Clemente Garcia-Rizo, Juan Undurraga, Maria Reinares, Anabel Martinez-Aran, Eduard Vieta, Norma Verdolini
Summary: This study found that emotional intelligence is preserved in patients after a first episode mania, but deficits can be observed in patients with chronic bipolar disorder. The severity of the illness and neurocognitive decline may contribute to impairments in emotional intelligence.
PSYCHOLOGICAL MEDICINE
(2023)
Review
Psychology, Developmental
Imanol Setien-Ramos, Jorge Lugo-Marin, Laura Gisbert-Gustemps, Emiliano Diez-Villoria, Maria Magan-Maganto, Ricardo Canal-Bedia, Josep Antoni Ramos-Quiroga
Summary: Eye-tracking studies have the potential to effectively differentiate between ASD and non-ASD groups, with fixation duration being an important factor. Active engaged tasks can reduce differences between ASD and non-ASD adults. Proportional fixation duration on eyes and non-social areas in non-active tasks is the optimal design for increasing sensitivity and specificity in ASD adults.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Public, Environmental & Occupational Health
Maria Soler Artigas, Cristina Sanchez-Mora, Paula Rovira, Laura Vilar-Ribo, Josep Antoni Ramos-Quiroga, Marta Ribases
Summary: This study investigates the causal relationship between ADHD and various related traits using GWAS data, providing new insights into the understanding and prevention of ADHD.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Psychology, Developmental
Jose Antonio Ramos-Quiroga, Vanesa Richarte, Isabel Soto, Maria Targhetta, John Ward, Nuria Perulero
Summary: This article estimates the prevalence and incidence of ADHD in Spain using a large database and analyzes variations in its treatment. The study finds higher rates of ADHD in children and males compared to adults and females. However, there is underdiagnosis and undertreatment of ADHD in adults, especially in females. The article calls for addressing the lack of diagnostic tools for adults and the variations in treatment across the country.
JOURNAL OF ATTENTION DISORDERS
(2023)
Article
Food Science & Technology
Jose A. Gallardo, Sonia Marin, Antonio J. Ramos, German Cano-Sancho, Vicente Sanchis
Summary: Enniatin B (ENNB) is a mycotoxin produced by moulds from the Fusarium genera, and its toxic effects are still not fully understood, therefore a safe reference exposure value has not been established. ENNB is the most prevalent emerging mycotoxin found in cereal-based products, but there is a lack of comprehensive exposure assessment studies. This study aimed to characterize the occurrence of ENNB and estimate the exposure of the Spanish and Catalan populations. The results showed a high occurrence of ENNB in all foodstuffs analyzed, with a strong correlation with deoxynivalenol levels. Children aged one-nine years had the highest exposure. This study highlights the need for further toxicological data and formal risk assessment considering the co-occurrence with deoxynivalenol.
Article
Psychology, Multidisciplinary
Mireia Forner-Puntonet, Laura Gisbert-Gustemps, Eudald Castell-Panisello, Mauricio Larrarte, Jesus Quintero, Gema Ariceta, Ferran Gran, Ignacio Iglesias-Serrano, Annabella Garcia-Moran, Gemma Espanol-Martin, Pol Ibanez-Jimenez, Josep Antoni Ramos-Quiroga
Summary: The objective of this study was to evaluate psychopathology, family stress, and coping strategies in families of pediatric solid organ transplantation (SOT) recipients compared to families of healthy children and adolescents. The results showed that families of SOT recipients exhibited higher levels of anxiety, stress related to childcare and parent-child interaction, and used more avoidance and religious coping strategies, while using fewer social support coping strategies. The study highlights the importance of providing psychological interventions and support for caregivers of SOT patients.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Clinical Neurology
Gara Arteaga-Henriquez, Laura Gisbert, Josep Antoni Ramos-Quiroga
Summary: Autism spectrum disorder (ASD) is a neurodevelopmental condition with unclear pathogenesis and limited effective therapies. There is evidence suggesting an association between ASD and immune/inflammatory processes, providing a potential pathway for new drug interventions. This review summarizes the latest evidence on the use of immunoregulatory and/or anti-inflammatory agents for managing ASD.
Article
Medicine, Research & Experimental
Silvia Alemany, Maria Soler-Artigas, Judit Cabana-Dominguez, Dana Fakhreddine, Natalia Llonga, Laura Vilar-Ribo, Amanda Rodriguez-Urrutia, Judit Palacio, Ana Maria Gonzalez-Castro, Beatriz Lobo, Carmen Alonso-Cotoner, Magnus Simren, Javier Santos, Josep Antoni Ramos-Quiroga, Marta Ribases
Summary: In this study, a multi-trait genome-wide association study was conducted to explore the genetic overlap between irritable bowel syndrome (IBS), neuroticism, depression, and anxiety. The results revealed a polygenic architecture for IBS and identified novel genetic variants associated with the disorder. The analysis also showed bidirectional causal effects between IBS and neuroticism and depression, as well as the genetic liability of IBS on anxiety. These findings contribute to our understanding of the genetic basis and relationships between gastrointestinal and mental disorders.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Neurosciences
Laura Vilar-Ribo, Judit Cabana-Dominguez, Lourdes Martorell, Josep Antoni Ramos-Quiroga, Sandra Sanchez-Roige, Abraham A. Palmer, Elisabet Vilella, Marta Ribases, Gerard Muntane, Maria Soler Artigas
Summary: There is evidence linking ADHD to reduced life expectancy. Individuals with ADHD have a higher mortality rate, which may be caused by unhealthy lifestyle behaviors, social adversity, and mental health problems. The study found a negative genetic correlation between ADHD and parental lifespan, indicating a common genetic background. These findings highlight the importance of ADHD as a health condition that can negatively affect lifespan and future life outcomes.
NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Psychiatry
Gemma Espanol-Martin, Mireia Pagerols, Raquel Prat, Cristina Rivas, Josep Antoni Ramos-Quiroga, Miquel Casas, Rosa Bosch
Summary: Prior research has shown that ADHD, SLD, and SES have an impact on educational outcomes. This study aimed to examine whether SES moderates the association between these neurodevelopmental disorders and academic achievement in Spanish students. The results indicate that ADHD and SLD have a significant impact on academic performance across different socioeconomic backgrounds.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Natalia Calvo, Jorge Lugo Marin, Raquel Vidal, Carla Sharp, Juan D. Duque, Josep-Antoni Ramos-Quiroga, Marc Ferrer
Summary: This study examines the capacity of the self-report Borderline Personality Features Scale Children-11 (BPFSC-11) to discriminate between Borderline Personality Disorder (BPD) and Attention-Deficit/Hyperactivity Disorder (ADHD) in adolescents. The results show that the total BPFSC-11 score has good discriminant capacity among adolescents diagnosed with BPD, ADHD, and healthy volunteers. However, different patterns of discriminative capacity were observed between the three groups for emotional dysregulation and impulsivity/recklessness factors.
BORDERLINE PERSONALITY DISORDER AND EMOTION DYSREGULATION
(2023)
Article
Food Science & Technology
Rogelio Santiago, Antonio J. Ramos, Ana Cao, Rosa Ana Malvar, Ana Butron
Summary: In temperate regions, maize kernels are susceptible to contamination by the fumonisin-producing fungus Fusarium verticillioides. Maize breeding plays a crucial role in reducing fumonisin contamination, and a pedigree selection program was initiated to obtain inbred lines (EPFUM) with resistance to kernel contamination. The study found that EPFUM hybrids showed better resistance to Fusarium ear rot and fumonisin contamination compared to commercial hybrids, indicating their potential in the market. White kernel hybrid EPFUM-4 x EP116 was highlighted as an alternative to dent hybrid cultivation due to its higher market value.
Article
Agronomy
Clara Melguizo, Belen Patino, Antonio J. Ramos, Covadonga Vazquez, Jessica Gil-Serna
Summary: Aspergillus flavus is a xerophilic fungus whose occurrence in vineyards is increasing, but the risk of grape contamination with aflatoxin needs further investigation.
Review
Behavioral Sciences
Miguel Garcia-Argibay, Lin Li, Ebba Du Rietz, Le Zhang, Honghui Yao, Johan Jendle, Josep A. Ramos-Quiroga, Marta Ribases, Zheng Chang, Isabell Brikell, Samuele Cortese, Henrik Larsson
Summary: We conducted a systematic review and meta-analysis to explore the association between ADHD and T2D. Our findings suggest that individuals with ADHD have a significantly increased risk of developing T2D, and this association can be largely explained by psychiatric comorbidities. Early identification and treatment of ADHD comorbidities may be crucial in reducing the risk of T2D in individuals with ADHD.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)