ERK-dependent phosphorylation of the linker and substrate-binding domain of HSP70 increases folding activity and cell proliferation

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System

(2018) Tania Morán Luengo et al.   MOLECULAR CELL

Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release

(2018) Manjeet Mukherjee et al.   Science Signaling

Recent advances in the structural and mechanistic aspects of Hsp70 molecular chaperones

(2018) Matthias P Mayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Phosphorylation of the C Terminus of Hsp70 Regulates the Mitochondrial Import of SOD2 and Redox Balance

(2018) Sara Zemanovic et al.   Cell Reports

The Hsp70–Hsp90 Chaperone Cascade in Protein Folding

(2018) Tania Morán Luengo et al.   TRENDS IN CELL BIOLOGY

The Hsp70 interdomain linker is a dynamic switch that enables allosteric communication between two structured domains

(2017) Charles A. English et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cracking the Chaperone Code: Cellular Roles for Hsp70 Phosphorylation

(2017) Nitika et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heat Shock Proteins and Cancer

(2017) Jianming Wu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

AMPylation targets the rate-limiting step of BiP’s ATPase cycle for its functional inactivation

(2017) Steffen Preissler et al.   eLife

Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways

(2017) et al.   Cancers

Experimental Milestones in the Discovery of Molecular Chaperones as Polypeptide Unfolding Enzymes

(2016) Andrija Finka et al.   Annual Review of Biochemistry

Targeting Hsp70: A possible therapy for cancer

(2016) Sanjay Kumar et al.   CANCER LETTERS

Hsp70 biases the folding pathways of client proteins

(2016) Ashok Sekhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamical Structures of Hsp70 and Hsp70-Hsp40 Complexes

(2016) Thomas Reid Alderson et al.   STRUCTURE

Heat Shock Proteins Promote Cancer: It's a Protection Racket

(2016) Stuart K. Calderwood et al.   TRENDS IN BIOCHEMICAL SCIENCES

How Hsp70 Molecular Machines Interact with Their Substrates to Mediate Diverse Physiological Functions

(2015) Eugenia M. Clerico et al.   JOURNAL OF MOLECULAR BIOLOGY

Mapping the conformation of a client protein through the Hsp70 functional cycle

(2015) Ashok Sekhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Phosphorylation: A Major Switch Mechanism for Metabolic Regulation

(2015) Sean J. Humphrey et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hsp70 Forms Antiparallel Dimers Stabilized by Post-translational Modifications to Position Clients for Transfer to Hsp90

(2015) Nina Morgner et al.   Cell Reports

Hsp70 in cancer: back to the future

(2014) M Y Sherman et al.   ONCOGENE

Structural characterization of the substrate transfer mechanism in Hsp70/Hsp90 folding machinery mediated by Hop

(2014) Sara Alvira et al.   Nature Communications

Systematic Functional Prioritization of Protein Posttranslational Modifications

(2012) Pedro Beltrao et al.   CELL

CDK-Dependent Hsp70 Phosphorylation Controls G1 Cyclin Abundance and Cell-Cycle Progression

(2012) Andrew W. Truman et al.   CELL

Identification and characterization of a 66–68-kDa protein as a methotrexate-binding protein in murine leukemia L1210 cells

(2012) Tuoen Liu et al.   CELL STRESS & CHAPERONES

C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances

(2012) P Muller et al.   ONCOGENE

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE