Phosphine-Catalyzed β-Selective Conjugate Addition of α-Fluoro-β-ketoamides to Allenic Esters

Enantioselective γ-addition of pyrazole and imidazole heterocycles to allenoates catalyzed by chiral phosphine

(2019) Haiyang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-Promoted Divergent Annulations of δ-Acetoxy Allenoates with α-Hydroxy-β-carbonyl Ester Derivatives: Synthesis of Tetrasubstituted Cyclopentadienes and Benzenes

(2019) Tong Xu et al.   ORGANIC LETTERS

Phosphine Sequentially Catalyzed Domino 1,6-Addition/Annulation: Access to Functionalized Chromans and Tetrahydroquinolines with an Ethynyl-Substituted All-Carbon Quaternary Center

(2019) Yannan Zhu et al.   ORGANIC LETTERS

Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

(2018) Yi Zhu et al.   CHEMICAL REVIEWS

Phosphine Organocatalysis

(2018) Hongchao Guo et al.   CHEMICAL REVIEWS

Phosphine-Catalyzed Asymmetric Organic Reactions

(2018) Huanzhen Ni et al.   CHEMICAL REVIEWS

Amide activation: an emerging tool for chemoselective synthesis

(2018) Daniel Kaiser et al.   CHEMICAL SOCIETY REVIEWS

Palladium-catalysed electrophilic aromatic C–H fluorination

(2018) Kumiko Yamamoto et al.   NATURE

Phosphine-Catalyzed Asymmetric Synthesis of α-Quaternary Amine via Umpolung γ-Addition of Ketimines to Allenoates

(2017) Peng Chen et al.   ORGANIC LETTERS

Decarbethoxylative Arylation Employing Arynes: A Metal-Free Pathway to Arylfluoroamides

(2017) Ekta Gupta et al.   ORGANIC LETTERS

Phosphine-Catalyzed Domino β/γ-Additions of Benzofuranones with Allenoates: A Method for Unsymmetrical 3,3-Disubstituted Benzofuranones

(2017) Zhusheng Huang et al.   ORGANIC LETTERS

Amino Acid-Derived Bifunctional Phosphines for Enantioselective Transformations

(2016) Tianli Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Stereoselective Organocatalyzed Synthesis of α-Fluorinated β-Amino Thioesters and Their Application in Peptide Synthesis

(2016) Elena Cosimi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Nucleophilicity of Persistent α-Monofluoromethide Anions

(2016) Zhe Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective aldol reactions with masked fluoroacetates

(2016) Jakub Saadi et al.   Nature Chemistry

Stereoselective Synthesis of α-Fluoro-γ-nitro Thioesters under Organocatalytic Conditions

(2016) Elena Cosimi et al.   ORGANIC LETTERS

Assembly of Fluorinated Quaternary Stereogenic Centers through Catalytic Enantioselective Detrifluoroacetylative Aldol Reactions

(2015) Chen Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective Organocatalytic Synthesis of Oxindoles with Adjacent Tetrasubstituted Stereocenters

(2015) Oliver D. Engl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-catalyzed regioselective Michael addition to allenoates

(2015) Vasudeva Rao Gandi et al.   CHEMICAL COMMUNICATIONS

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Regiodivergent Enantioselective γ-Additions of Oxazolones to 2,3-Butadienoates Catalyzed by Phosphines: Synthesis of α,α-Disubstituted α-Amino Acids and N,O-Acetal Derivatives

(2015) Tianli Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphine-Catalyzed Enantioselective γ-Addition of 3-Substituted Oxindoles to 2,3-Butadienoates and 2-Butynoates: Use of Prochiral Nucleophiles

(2014) Tianli Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trifluoromethylation of Alkenes with Concomitant Introduction of Additional Functional Groups

(2014) Hiromichi Egami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modern Carbon–Fluorine Bond Forming Reactions for Aryl Fluoride Synthesis

(2014) Michael G. Campbell et al.   CHEMICAL REVIEWS

Phosphine catalysis of allenes with electrophiles

(2014) Zhiming Wang et al.   CHEMICAL SOCIETY REVIEWS

Highly Enantioselective, Intermolecular Hydroamination of Allenyl Esters Catalyzed by Bifunctional Phosphinothioureas

(2014) Yuan-Qing Fang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Difluoro(sulfinato)methylation of N-Sulfinyl Imines Facilitated by 2-Pyridyl Sulfone: Stereoselective Synthesis of Difluorinated β-Amino Sulfonic Acids and Peptidosulfonamides

(2013) G. K. Surya Prakash et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric CN Bond Formation: Phosphine-Catalyzed Intra- and Intermolecular γ-Addition of Nitrogen Nucleophiles to Allenoates and Alkynoates

(2013) Rylan J. Lundgren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in nucleophilic phosphine catalysis of alkenes, allenes, alkynes, and MBHADs

(2013) Yi Chiao Fan et al.   CHEMICAL COMMUNICATIONS

Direct Synthesis of Diverse β-Fluoroethylamines by a Multicomponent Protocol

(2013) G. K. Surya Prakash et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tuning Catalysts to Tune the Products: Phosphine-Catalyzed Aza-Michael Addition Reaction of Hydrazones with Allenoates

(2013) Erqing Li et al.   Chemistry-An Asian Journal

Domino Cyclization Initiated by Cross-Rauhut-Currier Reactions

(2013) Peizhong Xie et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Copper-Mediated Fluorination of Arylboronate Esters. Identification of a Copper(III) Fluoride Complex

(2013) Patrick S. Fier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphine-catalyzed intramolecular γ-umpolung addition of α-aminoalkylallenic esters: facile synthesis of 3-carbethoxy-2-alkyl-3-pyrrolines

(2012) Ian P. Andrews et al.   CHEMICAL COMMUNICATIONS

Asymmetric Aldol Reactions of Heterocyclic Dienolsilanes and α,β-Unsaturated Carbonyl Derived Dienolsilanes

(2012) Fener Chen et al.   SYNTHESIS-STUTTGART

Copper-catalyzed trifluoromethylation of aryl boronic acids using a CF3+ reagent

(2011) Jun Xu et al.   CHEMICAL COMMUNICATIONS

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

Phosphane-Catalyzed Umpolung Addition Reaction of Nucleophiles to Ethyl 2-Methyl-2,3-butadienoate

(2011) Xiao-Yang Guan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Phosphine-Initiated General Base Catalysis: Facile Access to Benzannulated 1,3-Diheteroatom Five-Membered Rings via Double-Michael Reactions of Allenes

(2011) Judy Szeto et al.   ORGANIC LETTERS

Phosphine-Catalyzed β′-Umpolung Addition of Nucleophiles to Activated α-Alkyl Allenes

(2011) Tioga J. Martin et al.   ORGANIC LETTERS

Phosphine-catalyzed highly diastereoselective [3+2] cyclization of isatin derived electron-deficient alkenes with α-allenic esters

(2010) Xiu-Chun Zhang et al.   CHEMICAL COMMUNICATIONS

Electrophilic trifluoromethylation of arenes and N-heteroarenes using hypervalent iodine reagents

(2010) Matthias S. Wiehn et al.   JOURNAL OF FLUORINE CHEMISTRY

Aromatic trifluoromethylation catalytic in copper

(2009) Masahiro Oishi et al.   CHEMICAL COMMUNICATIONS

Enantioselective catalysis and complexity generation from allenoates

(2009) Bryan J. Cowen et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Carbon−Carbon Bond Formation γ to a Carbonyl Group: Phosphine-Catalyzed Addition of Nitromethane to Allenes

(2009) Sean W. Smith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

 -Fluoro- -nitro(phenylsulfonyl)methane as a fluoromethyl pronucleophile: Efficient stereoselective Michael addition to chalcones

(2009) G. K. S. Prakash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphine-triggered synthesis of functionalized cyclic compounds

(2008) Long-Wu Ye et al.   CHEMICAL SOCIETY REVIEWS

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS