Residual inflammatory risk associated with interleukin-18 and interleukin-6 after successful interleukin-1β inhibition with canakinumab: further rationale for the development of targeted anti-cytokine therapies for the treatment of atherothrombosis

Anticytokine Agents

(2019) Paul M Ridker   CIRCULATION RESEARCH

OUP accepted manuscript

(2018)   EUROPEAN HEART JOURNAL

All roads lead to IL-6: A central hub of cardiometabolic signaling

(2018) Peter Libby et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial

(2018) Paul M Ridker et al.   LANCET

The NLRP3 inflammasome in acute myocardial infarction

(2017) Stefano Toldo et al.   Nature Reviews Cardiology

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

From C-Reactive Protein to Interleukin-6 to Interleukin-1

(2016) Paul M Ridker   CIRCULATION RESEARCH

Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial

(2016) Ola Kleveland et al.   EUROPEAN HEART JOURNAL

Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter

(2015) Jing Wang et al.   NATURE MEDICINE

Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis

(2013) S. Kaptoge et al.   EUROPEAN HEART JOURNAL

Interleukin-18: a potent pro-inflammatory cytokine in atherosclerosis: EXPERT'S PERSPECTIVE

(2012) L. Badimon   CARDIOVASCULAR RESEARCH

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

(2012)   LANCET

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

(2012)   LANCET