期刊
ENVIRONMENTAL POLLUTION
卷 252, 期 -, 页码 1002-1009出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2019.06.041
关键词
Economic growth; Estimated daily intake; Fish; Parabens; Risk assessment; Temporal variation
资金
- National Natural Science Foundation of China [21677094, 41731279]
- Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program [2017BT01Z032]
- Shenzhen Municipal Government Research Projects [JCYJ20160428143348745: X11120170413102320786]
Parabens are alkyl esters widely used as preservatives in foodstuffs, cosmetics, and pharmaceuticals. Taihu Lake is the third largest freshwater lake in China. However, there is no information available on the occurrence of parabens in Taihu Lake. To investigate contamination of parabens in Taihu Lake and the influence of human activities on contamination levels, 199 fish samples, comprising five species, were collected from Taihu Lake from 2009 to 2017. Five parabens, including methylparaben (MeP), ethylparaben (EtP), propylparaben (PrP), butylparaben (BuP), and benzylparaben (BeP), were quantitated using an isotope dilution LC-MS/MS method. The total concentrations of the five parabens ranged from 261 to 1710 pg/g wet weight (ww) with an average of 642 pg/g ww. The predominant compounds were MeP, EtP, and PrP, whose amounts accounted for more than 95% of the total amounts. No significant differences in the concentrations of parabens among the five fish species were observed, suggesting no interspecies differences in bioaccumulation of these compounds. Sigma(5)parabens in fish showed temporal variations with the means ranging between 532 and 772 pg/g ww during years. The levels of parabens were generally consistent with the economic development and urbanization rates of the regions surrounding Taihu Lake. The typical and high estimated daily intake (EDI) of parabens were 0.53 and 0.91 ng/kg-bw/day for children, and 0.46 and 0.79 ng/kg-bw/day for adults based on calculations using the means and the 95th concentrations, respectively. The EDIs were much lower than the reference dose values, suggesting that there are no obvious health risks posed by fish consumption. (C) 2019 Elsevier Ltd. All rights reserved.
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