Novel antimicrobial peptide discovery using machine learning and biophysical selection of minimal bacteriocin domains

The Modification and Design of Antimicrobial Peptide

(2018) Yidan Gao et al.   CURRENT PHARMACEUTICAL DESIGN

Rational design of syn-safencin, a novel linear antimicrobial peptide derived from the circular bacteriocin safencin AS-48

(2018) Francisco R. Fields et al.   JOURNAL OF ANTIBIOTICS

Bacteriocins of lactic acid bacteria: extending the family

(2016) Patricia Alvarez-Sieiro et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Role of Aromatic Amino Acids in Lipopolysaccharide and Membrane Interactions of Antimicrobial Peptides for Use in Plant Disease Control

(2016) Aritreyee Datta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Total Synthesis of Circular Bacteriocins by Butelase 1

(2016) Xinya Hemu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antimicrobial Peptide Structure and Mechanism of Action: A Focus on the Role of Membrane Structure

(2015) Tzong-Hsien Lee et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The bacteriocin AS-48 requires dimer dissociation followed by hydrophobic interactions with the membrane for antibacterial activity

(2015) Rubén Cebrián et al.   JOURNAL OF STRUCTURAL BIOLOGY

Bioengineering Lantibiotics for Therapeutic Success

(2015) Des Field et al.   Frontiers in Microbiology

SaeRS-Dependent Inhibition of Biofilm Formation in Staphylococcus aureus Newman

(2015) David Cue et al.   PLoS One

Strategies employed in the design and optimization of synthetic antimicrobial peptide amphiphiles with enhanced therapeutic potentials

(2014) Zhan Yuin Ong et al.   ADVANCED DRUG DELIVERY REVIEWS

A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics

(2014) Mohamed S. Donia et al.   CELL

Cationic antimicrobial peptides as potential new therapeutic agents in neonates and children

(2014) Martin Ashby et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Prediction of Linear Cationic Antimicrobial Peptides Based on Characteristics Responsible for Their Interaction with the Membranes

(2014) Boris Vishnepolsky et al.   Journal of Chemical Information and Modeling

Bacteriocin AS-48 binding to model membranes and pore formation as revealed by coarse-grained simulations

(2013) Victor L. Cruz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

BAGEL3: automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides

(2013) Auke J. van Heel et al.   NUCLEIC ACIDS RESEARCH

Role of Amphiphilicity in the Design of Synthetic Mimics of Antimicrobial Peptides with Gram-Negative Activity

(2013) Hitesh D. Thaker et al.   ACS Medicinal Chemistry Letters

The Biofilm-Specific Antibiotic Resistance Gene ndvB Is Important for Expression of Ethanol Oxidation Genes in Pseudomonas aeruginosa Biofilms

(2012) T. Beaudoin et al.   JOURNAL OF BACTERIOLOGY

Bacteriocins — a viable alternative to antibiotics?

(2012) Paul D. Cotter et al.   NATURE REVIEWS MICROBIOLOGY

AS-48 bacteriocin: close to perfection

(2011) Marina Sánchez-Hidalgo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Designing antimicrobial peptides: form follows function

(2011) Christopher D. Fjell et al.   NATURE REVIEWS DRUG DISCOVERY

Interaction of W-Substituted Analogs of Cyclo-RRRWFW with Bacterial Lipopolysaccharides: the Role of the Aromatic Cluster in Antimicrobial Activity

(2010) Mojtaba Bagheri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of linear forms of the circular enterocin AS-48 obtained by limited proteolysis

(2008) Manuel Montalbán-López et al.   FEBS LETTERS

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols

Discovery of a widely distributed toxin biosynthetic gene cluster

(2008) S. W. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA