Article
Medicine, General & Internal
William Myles, Catherine Dunlop, Sally A. McFadden
Summary: Low-dose atropine can slow the progression of myopia in children, especially in the 'slow' progression group. However, rebound occurred in three-quarters of eyes after cessation of atropine. Adverse effects were observed in 69% of patients, with dilated pupils being more common in children with blue eyes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Biochemical Research Methods
Rohan P. J. Hughes, Scott A. Read, Michael J. Collins, Stephen J. Vincent
Summary: This study examined anterior corneal, internal ocular, and total ocular higher order aberrations (HOA's), and retinal image quality in a non-myopic, paediatric cohort. The study found that internal ocular HOA's were higher in magnitude but partially compensated, resulting in reduced levels of HOA's and excellent retinal image quality. Weak correlations were observed between HOA's and age, sex, refractive error, and axial length. These findings provide an improved understanding of the optics and retinal image quality of children's eyes.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Biochemical Research Methods
Dibyendu Pusti, Chloe Degre Kendrick, Yifei Wu, Qiuzhi Ji, Hae Won Jung, Geunyoung Yoon
Summary: The quantitative evaluation of peripheral ocular optics is crucial for myopia research and studying visual performance in individuals with normal and compromised central vision. We have developed a widefield scanning wavefront sensor (WSWS) that can scan along any retinal meridian while maintaining natural central fixation. The WSWS utilizes a unique scanning method involving a motorized rotary stage and a goniometer to scan horizontally and vertically, allowing for the evaluation of four meridians within 5 seconds.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Neurosciences
Gaku Kiuchi, Takahiro Hiraoka, Yuta Ueno, Toshifumi Mihashi, Tetsuro Oshika
Summary: This study found that patient age and corneal astigmatism have a significant influence on corneal higher-order aberrations (HOAs), while refractive status (myopia, emmetropia, hyperopia) does not have a significant association with corneal HOAs. Age and corneal astigmatism were found to be correlated with aberrations in multiple regression analysis, but spherical equivalent refractive error and refractive status were not.
Article
Medicine, General & Internal
Natsuki Kusada, Norihiko Yokoi, Chie Sotozono
Summary: This study used a videokeratographer to continuously measure higher-order aberrations (HOAs) in dry eye disease (DED) patients and investigated the factors that determine HOAs. The results show that HOAs at 1 or 2 seconds after eye opening can reflect tear film instability and corneal epithelial damage in DED patients. This finding may be helpful for the rapid and non-invasive detection and evaluation of visual function decline in DED patients with various clinical features.
Article
Ophthalmology
Meenakshi Wadhwani, Praveen Vashist, Suraj Senjam Singh, Vivek Gupta, Noopur Gupta, Rohit Saxena
Summary: This study aimed to determine the prevalence of myopia at the community level. A population-based, cross-sectional study was conducted in Delhi to screen the visual acuity of 20,000 children aged 0-15 years. The results showed a prevalence of 3.7% myopia, with 45% of cases being uncorrected.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Denis Plotnikov, Jiangtian Cui, Rosie Clark, Juho Wedenoja, Olavi Parssinen, J. Willem L. Tideman, Jost B. Jonas, Yaxing Wang, Igor Rudan, Terri L. Young, David A. Mackey, Louise Terry, Cathy Williams, Jeremy A. Guggenheim
Summary: The genetic variants that regulate eye size in emmetropic eyes are distinct from those that confer susceptibility to myopia, indicating that different biological pathways are involved in normal eye growth and myopia development.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Ophthalmology
James S. Wolffsohn, Monica Jong, Earl L. Smith, Serge R. Resnikoff, Jost B. Jonas, Nicola S. Logan, Ian Morgan, Padmaja Sankaridurg, Kyoko Ohno-Matsui
Summary: The International Myopia Institute (IMI) is focused on advancing research, education, and management in the field of myopia to reduce the incidence of future vision impairment and blindness associated with increasing myopia. By promoting collaboration and knowledge sharing, IMI addresses issues such as pathologic myopia, the impact of myopia, risk factors, accommodation, binocular vision, and myopia prevention.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Ophthalmology
Hassan Hashemi, Mehdi Khabazkhoob, Elham Azizi, Rafael Iribarren, Carla Lanca, Andrzej Grzybowski, Jos J. Rozema, Mohammad Hassan Emamian, Akbar Fotouhi
Summary: The study found that the crystalline lens power decreases and thickness slightly increases in 6 to 12-year-old children over a three-year period. These changes are associated with refractive errors, place of residence, age, gender, and outdoor activity time.
Article
Multidisciplinary Sciences
Einat Shneor, David P. Pinero, Ravid Doron
Summary: This study found that despite good visual acuity, patients with mild keratoconus showed decreased contrast sensitivity and increased higher-order aberrations compared to controls. Most higher-order aberrations were negatively correlated with contrast sensitivity.
SCIENTIFIC REPORTS
(2021)
Article
Public, Environmental & Occupational Health
Yuxia You, Junxia Fu, Ming Xu, Yali Song, Huanfen Zhou, Shihui Wei
Summary: This population-based study investigated the refractive status and prevalence of refractive error in Chinese preschool children aged 1-6 years old. The study found that the prevalence of myopia decreased with age in preschool children younger than 5 years old and then slightly increased at 5-6 years, potentially indicating early signs of myopia in school-age children. The research highlights the need for greater attention to be given to children in this age group.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Ophthalmology
Na Li, Weiping Lin, Kailang Zhang, Bingqin Li, Qiang Su, Bei Du, Ruihua Wei
Summary: This study compares axial elongation, relative corneal refractive power (RCRP) distribution within the pupillary diameter, and corneal higher-order aberrations (HOAs) in myopic children wearing orthokeratology (ortho-k) lenses with different back optic zone diameters (BOZD). The results show that ortho-k lenses with smaller BOZD have better myopia control efficacy, induce a steeper distribution of the RCRP profile within the pupillary diameter, and induce greater increases in corneal total HOAs and horizontal coma (Z13).
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Medicine, General & Internal
Yih-Shiuan Kuo, May-Yung Yen, Pei-Yu Lin
Summary: The study revealed that 0.25% atropine caused a hyperopic shift in spherical equivalent and resulted in significant changes in total spherical aberration and internal spherical aberration in myopic children. However, the differences in corneal spherical aberration were not significant. This suggests that inhibiting accommodation may have a potential role in preventing myopic progression.
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
(2021)
Article
Multidisciplinary Sciences
Yequan Huang, Jingyun Guo, Yu Guo, Yan Cui, Zhechuang Li, Xuechuan Dong, Xiaolin Ning
Summary: This paper introduces a novel wide-angle refraction measurement method called Refraction Topography (RT), and evaluates its agreement with simulation results and expected refraction. RT utilizes a refraction algorithm on fundus images to measure refraction. Unlike traditional methods, RT requires the subject to stare at a stationary target. The study demonstrates the agreement between the test results obtained using RT, simulation results, and expected refraction on three test eyes.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Carter J. Payne, Courtney R. Webster, Majid Moshirfar, Jaiden J. Handlon, Yasmyne C. Ronquillo, Phillip C. Hoopes
Summary: This study presents a retrospective report on the one-year visual outcomes of Small Incision Lenticule Extraction (SMILE) for myopia and myopic astigmatism. The results indicate that SMILE is a safe and effective treatment with positive clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Ophthalmology
Muriel M. Schornack, Stephen J. Vincent, Maria K. Walker
Summary: Intraocular pressure (IOP) is regulated by complex systems and the use of scleral lenses (SLs) may disrupt these processes. This review examines the anatomical and physiological control of IOP, explores the potential effects of SLs on these mechanisms, and analyzes studies that have attempted to measure the impact of SLs on IOP. Accurate assessment of IOP during SL wear is challenging, but various techniques and instruments have been used to measure IOP before and after lens application, as well as on the peripheral cornea or conjunctiva overlying the sclera. Some conflicting results have been reported regarding changes in IOP during SL wear, particularly for short durations. Long-term effects of SL wear on IOP in habitual wearers are still under-researched. It is important to consider the impact of SLs on corneal biomechanical properties and monitor other risk factors for glaucoma in SL wearers.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Ophthalmology
Ranjay Chakraborty, Michael J. Collins, Henry Kricancic, Brett Davis, David Alonso-Caneiro, Fan Yi, Karthikeyan Baskaran
Summary: This study aimed to examine the effects of stimulation of intrinsically photosensitive retinal ganglion cells (ipRGCs) on axial length changes in young adults. The study found that stimulation of ipRGCs using blue light caused an increase in axial length. However, this effect was not observed in myopic defocus conditions.
JOURNAL OF OPTOMETRY
(2023)
Article
Ophthalmology
Tabitha M. Scott BKin, Eugene R. Ting, Stephen J. Vincent, Graham A. Lee
Summary: This study reviewed the long-term outcomes of cyclodiode treatment in patients with refractory glaucoma. The results showed that cyclodiode can effectively reduce intraocular pressure and the need for medications in the long term, but complications such as hypotony and phthisis may occur.
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Scott A. Read, Shelley Hopkins, Alex A. Black, Sharon A. Bentley, John Scott, Joanne M. Wood
Summary: Although studies have examined vision conditions in Indigenous children in urban and regional areas of Australia, there is limited research on children in remote regions. This study found that up to 1 in 3 children in a very remote region had a vision condition, with many of these conditions being uncorrected and undetected.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Ophthalmology
Rebecca A. Cox, Scott A. Read, Shelley Hopkins, Joanne M. Wood
Summary: This study investigated the ocular biometry of Aboriginal and Torres Strait Islander children in Australia, finding differences in refractive error, lens power, central corneal thickness, and intraocular pressure compared to non-Indigenous children, which may have implications for the development of refractive error and ocular disease later in life.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Biology
Yoel F. Garcia-Marin, David Alonso-Caneiro, Damien Fisher, Stephen J. Vincent, Michael J. Collins
Summary: Anterior segment optical coherence tomography (AS-OCT) is a fundamental ophthalmic imaging technique that can provide quantitative metrics for clinical decision making. In this study, a patch-based convolutional neural network (CNN) was used to accurately segment the cornea's boundaries. The performance of the model was assessed based on the number of classes and image quality, revealing comparable results to other established segmentation methods.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Ophthalmology
Dinesh Kaphle, Katrina L. Schmid, Marwan Suheimat, Scott A. Read, David A. Atchison
Summary: The purpose of this study was to investigate the relationship between peripheral choroid thickness and eye length changes during accommodation. The results showed that eye length increased with accommodation, while the choroid thinned. The thinning of the choroid accounted for approximately 60% of the eye length increase.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Ophthalmology
Vyasa H. H. Bliss, Nathan Branjerdporn, Peng Jia Ooi, Li Mei Teo, Jervis Tu, Justin Yeh, Michael J. J. Collins, Stephen J. J. Vincent
Summary: The aim of this study was to compare the magnitude of corneal oedema induced following short-term reverse piggyback scleral lens wear and standard scleral lens wear. The results showed that the highly oxygen-permeable reverse piggyback system did not induce a clinically or statistically greater magnitude of central corneal oedema compared with standard scleral lens wear.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Ophthalmology
Rohan P. J. Hughes, Scott A. Read, Michael J. Collins, Stephen J. Vincent
Summary: This study investigates the changes in higher order aberrations and retinal image quality during accommodation in children with different refractive errors. The results show that near work has a greater impact on myopic children, while non-myopic children show greater changes in spherical aberration during accommodation.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Biochemical Research Methods
Rohan P. J. Hughes, Scott A. Read, Michael J. Collins, Stephen J. Vincent
Summary: This study examined anterior corneal, internal ocular, and total ocular higher order aberrations (HOA's), and retinal image quality in a non-myopic, paediatric cohort. The study found that internal ocular HOA's were higher in magnitude but partially compensated, resulting in reduced levels of HOA's and excellent retinal image quality. Weak correlations were observed between HOA's and age, sex, refractive error, and axial length. These findings provide an improved understanding of the optics and retinal image quality of children's eyes.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Ophthalmology
Barsha Lal, David Alonso-Caneiro, Scott A. Read, Andrew Carkeet
Summary: The study aims to investigate longitudinal changes in retinal and choroidal OCT-A indices over 1 year among healthy children and young adults. The results showed significant changes in retinal OCT-A indices over 1 year among children but not adults, while choroidal OCT-A indices remained stable.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Ophthalmology
Nasrin Moghadas Sharif, Hosein Hoseini-Yazdi, Ramin Daneshvar, Hema Radhakrishnan, Nasser Shoeibi, Asieh Ehsaei, Michael J. Collins
Summary: The study found small but significant seasonal changes in anterior segment angle parameters, refractive error, and IOP in healthy young adult males, with narrower anterior segment angle dimensions, higher IOP, and more myopic refraction during the winter.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Ophthalmology
Shelley Hopkins, Scott A. Read, Rebecca A. Cox, Bright A. Oduro, Niall Strang, Joanne M. Wood
Summary: This study investigated the impact of clinically significant hyperopia on visual function in schoolchildren and compared the ability of different screening tests to detect it. Results showed significant differences in visual function between children with clinically significant hyperopia and those with emmetropia/low hyperopia. Combining measures of DVA and NVA and the difference in DVA through a plus lens demonstrated good discriminative ability for detecting clinically significant hyperopia.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Computer Science, Artificial Intelligence
Jason Kugelman, David Alonso-Caneiro, Scott A. Read, Stephen J. Vincent, Michael J. Collins
Summary: Training deep learning methods for OCT retinal and choroidal layer segmentation is challenging due to limited data availability and privacy concerns. This study proposes an enhanced StyleGAN2-based data augmentation method combined with semi-supervised learning using a novel cross-localisation technique. By incorporating styles from unlabelled data with labelled data, the method increases the diversity of synthetic data. Through optimization and targeted model selection, the method demonstrates improved performance in OCT retinal and choroidal layer segmentation.
COMPUTER VISION AND IMAGE UNDERSTANDING
(2023)
