期刊
CHIRALITY
卷 31, 期 10, 页码 776-812出版社
WILEY
DOI: 10.1002/chir.23103
关键词
asymmetric synthesis; biologically active compounds; chiral auxiliaries; Corey's chiral auxiliary; Evans' oxazolidinones
This review article describes the use of some of the most popular chiral auxiliaries in the asymmetric synthesis of biologically active compounds. Chiral auxiliaries derived from naturally occurring compounds, such as amino acids, carbohydrates, and terpenes, are considered essential tools for the construction of highly complex molecules. We highlight the auxiliaries of Evans, Corey, Yamada, Enders, Oppolzer, and Kunz, which led to remarkable progress in asymmetric synthesis in the last decades and continue to bring advances until the present day.
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