RNA‐binding protein SFPQ cooperates with HDAC1 to suppress CD40 transcription in pulmonary adventitial fibroblasts

A novel human lncRNA SANT1 cis-regulates the expression of SLC47A2 by altering SFPQ/E2F1/HDAC1 binding to the promoter region in renal cell carcinoma

(2019) Zhangzhao Gao et al.   RNA Biology

Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins

(2018) Jie Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis

(2018) Hsi-Wen Yeh et al.   NATURE CELL BIOLOGY

Tanshinone II A Attenuates TNF-α-Induced Expression of VCAM-1 and ICAM-1 in Endothelial Progenitor Cells by Blocking Activation of NF-κB

(2016) Jin-Xiu Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Interruption of CD40 Pathway Improves Efficacy of Transplanted Endothelial Progenitor Cells in Monocrotaline Induced Pulmonary Arterial Hypertension

(2015) YanYun Pan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Transcriptional upregulation of microtubule-associated protein 2 is involved in the protein kinase A-induced decrease in the invasiveness of glioma cells

(2015) Yuxi Zhou et al.   NEURO-ONCOLOGY

The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation

(2015) Mihwa Lee et al.   NUCLEIC ACIDS RESEARCH

Arginine methylation and citrullination of splicing factor proline- and glutamine-rich (SFPQ/PSF) regulates its association with mRNA

(2015) Ambrosius P. Snijders et al.   RNA

Histone H3 K27 acetylation marks a potent enhancer element on the adipogenic master regulator gene Pparg2

(2014) Muhammad Khairul Ramlee et al.   CELL CYCLE

Adventitial Fibroblasts Induce a Distinct Proinflammatory/Profibrotic Macrophage Phenotype in Pulmonary Hypertension

(2014) Karim C. El Kasmi et al.   JOURNAL OF IMMUNOLOGY

Serotonin drives the activation of pulmonary artery adventitial fibroblasts and TGF-β1/Smad3-mediated fibrotic responses through 5-HT2A receptors

(2014) Chunyan Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Long Noncoding RNA NEAT1-Dependent SFPQ Relocation from Promoter Region to Paraspeckle Mediates IL8 Expression upon Immune Stimuli

(2014) Katsutoshi Imamura et al.   MOLECULAR CELL

A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice

(2014) Chen-Chun Pai et al.   Nature Communications

MicroRNA-124 Controls the Proliferative, Migratory, and Inflammatory Phenotype of Pulmonary Vascular Fibroblasts

(2013) Daren Wang et al.   CIRCULATION RESEARCH

Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension

(2012) Adil Anwar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Modern Age Pathology of Pulmonary Arterial Hypertension

(2012) Elvira Stacher et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hypoxia induces unique proliferative response in adventitial fibroblasts by activating PDGFβ receptor-JNK1 signalling

(2012) Evgeniy Panzhinskiy et al.   CARDIOVASCULAR RESEARCH

CD40 Ligand: A neo-inflammatory molecule in vascular diseases

(2011) Ghada S. Hassan et al.   IMMUNOBIOLOGY

Emergence of Fibroblasts with a Proinflammatory Epigenetically Altered Phenotype in Severe Hypoxic Pulmonary Hypertension

(2011) M. Li et al.   JOURNAL OF IMMUNOLOGY

Emerging Pathogenetic Mechanisms of Pulmonary Arterial Hypertension: Nitric Oxide and More

(2011) Young Dae Kim   Korean Circulation Journal

Epigenetic Regulation of Thy-1 by Histone Deacetylase Inhibitor in Rat Lung Fibroblasts

(2010) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

PTB-associated Splicing Factor (PSF) Functions as a Repressor of STAT6-mediated Igϵ Gene Transcription by Recruitment of HDAC1

(2010) Lijie Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methylation determines fibroblast activation and fibrogenesis in the kidney

(2010) Wibke Bechtel et al.   NATURE MEDICINE

Emerging Concepts in the Pathogenesis of Lung Fibrosis

(2009) William D. Hardie et al.   AMERICAN JOURNAL OF PATHOLOGY

Paraspeckles: nuclear bodies built on long noncoding RNA

(2009) Charles S. Bond et al.   JOURNAL OF CELL BIOLOGY

The CD40/CD40 Ligand System

(2009) Charalambos Antoniades et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Determinants of initiation and progression of idiopathic pulmonary fibrosis

(2009) Robert Matthew KOTTMANN et al.   RESPIROLOGY

Thy-1 Promoter Hypermethylation

(2008) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKC  in the pulmonary artery adventitia

(2008) M. Das et al.   CARDIOVASCULAR RESEARCH