Article
Plant Sciences
Jenny Hagenblad, Robin Abbey-Lee, Leah Bashford, Tytti Vanhala, Matti W. W. Leino
Summary: In this study, genetic characterization of Fennoscandian landraces of naked barley was conducted. The analysis identified three groups: naked two-row barley likely originating from Asia, naked six-row barley likely originating from the eastern Himalayas and introduced in the 19th century, and naked six-row barley genetically related to the original Fennoscandian hulled barley. The findings suggest that the ancient form of naked barley was introduced in the Neolithic, and gene flow between naked and hulled barleys resulted in a genetically distinct Fennoscandian barley.
VEGETATION HISTORY AND ARCHAEOBOTANY
(2023)
Article
Biochemical Research Methods
Junjun Liang, Ling Yi, Lilan Li, Haili Zhang, Yunshu Zhang, Guangbing Deng, Hai Long, Maoqun Yu
Summary: This study identified 54 PP2C genes in Tibetan hulless barley and found that 12 of them were significantly induced under dehydration stress. HvPP2C59, belonging to group F, showed a remarkable continuously upregulated pattern during dehydration stress. Silencing HvPP2C59 gene resulted in increased leaf water loss rate, decreased survival rate, and retarded vegetative growth in hulless barley.
PLANT MOLECULAR BIOLOGY REPORTER
(2022)
Article
Biochemistry & Molecular Biology
Junjun Liang, Haili Zhang, Ling Yi, Yawei Tang, Hai Long, Maoqun Yu, Guangbing Deng
Summary: This study investigated a new gene HvLRX in Tibetan hulless barley, revealing its important role in drought resistance. HvLRX expression is influenced by light intensity, dehydration, and drought stress, and it is also crucial for plant development.
Article
Plant Sciences
Xiaxia Tian, Qiang Yao, Zedong Zhang, Xiangrui Cheng, Jianfeng Qin, Zhensheng Kang, Jie Zhao
Summary: This study reports the first occurrence of crown rust on barley in China, and reveals different levels of host resistance to the pathogen among different plant species.
Article
Agriculture, Multidisciplinary
Manh Tuan Ha, Phuong Thao Tran, Huynh Nguyen Khanh Tran, Okwha Kim, Jeong Ah Kim, Jeong-Hyung Lee, Byung Sun Min
Summary: The alkaloid fraction of barley grass significantly inhibited osteoclast formation and protected bones. Compound 5 in particular showed strong suppression of osteoclast formation and related signaling pathways, making it a potential candidate for treating osteolytic bone diseases.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Agronomy
Giorgia Capasso, Giorgia Santini, Mariagioia Petraretti, Sergio Esposito, Simone Landi
Summary: Barley, a major crop globally, has been genetically improved for higher yields but weakened in resilience to adverse environments. Climate change demands crop varieties that can grow under stress conditions, where wild varieties and landraces may play a crucial role.
Article
Agronomy
Waleed Amjad Khan, Sergey Shabala, Tracey Ann Cuin, Meixue Zhou, Beth Penrose
Summary: This study found that higher levels of zinc in the growth substrate lead to increased zinc concentrations in aboveground tissues and grains of barley, with significant differences in zinc concentrations observed between different cultivars. Zinc-efficient cultivars exhibited more efficient translocation and remobilisation of zinc. Selective breeding and optimal zinc fertilisation can help achieve target zinc concentrations in barley. Further exploration of major quantitative trait loci (QTLs) and candidate genes related to desirable zinc phenotypes could enhance our understanding of zinc uptake mechanisms in barley.
Article
Plant Sciences
Jingqi Suo, Chenlu Zhou, Zhanghui Zeng, Xipu Li, Hongwu Bian, Junhui Wang, Muyuan Zhu, Ning Han
Summary: This study identified different transcription regulation pathways between calli formed from immature and mature embryos in barley, revealing significant changes in gene expression profiles induced by auxin-rich medium within 48 hours. The differential expression of IAA genes suggests the involvement of auxin response in regulating cell reprogramming during callus formation. Additionally, epigenetic regulators and key genes involved in meristem development were found to play crucial roles in determining the acquisition of competency, contributing to improved transformation efficiency in barley.
Article
Plant Sciences
Qiongxian Lu, Christoph Dockter, Nick Sirijovski, Shakhira Zakhrabekova, Udda Lundqvist, Per L. Gregersen, Mats Hansson
Summary: The study revealed that mutations in the Ert-c and Ert-d genes cause changes in barley plant architecture, with mutant ert-d.7 carrying mutations in both ert-d and ert-c. Different levels of spike structural changes were observed in the mutants, and different genetic association patterns indicated distinct translocation breakpoints in these two mutants.
Article
Biochemistry & Molecular Biology
Haoyingye Yao, Yuxiao Wang, Junyi Yin, Shaoping Nie, Mingyong Xie
Summary: Arabinoxylan (HBAX-60) was fractionated from alkaline-extracted arabinoxylan (HBAX) in hull-less barley, composed mainly of arabinose and xylose with a low-branched xylan backbone and other residues. Analysis showed a random coil conformation in solution, providing insights for further research and applications of this arabinoxylan.
Article
Plant Sciences
Saglara Mandzhieva, Victor Chaplygin, Natalia Chernikova, Aleksey Fedorenko, Marina Voloshina, Tatiana Minkina, Vishnu D. Rajput, Maria Elinson, Ming Hung Wong
Summary: Cadmium and zinc are heavy metals that can be dangerous and pollute the environment. This study investigated the individual and combined impact of Cd and Zn contamination on spring barley, and analyzed the accumulation and distribution of these elements in the plant. The results showed that Cd accumulated more intensely than Zn, and both metals suppressed plant growth and caused structural changes in root and leaf tissues. Furthermore, the study found that zinc had a protective effect against high doses of Cd. These findings provide insights into the phytotoxicity induced by Cd and Zn and can help prevent these elements from entering the food chain.
Article
Plant Sciences
Sebastian Zahn, Thomas Schmutzer, Klaus Pillen, Andreas Maurer
Summary: This study investigated the genetic control of barley peduncle morphology and identified three major QTL regions on chromosomes 2H and 3H impacting peduncle traits. The exotic allele at the QTL on chromosome 3H improved all three investigated traits, showing potential for enhancing plant stability and straw biomass production.
Article
Environmental Sciences
Magdalena Kusiak, Malgorzata Sierocka, Michal Swieca, Sylwia Pasieczna-Patkowska, Mohamed Sheteiwy, Izabela Josko
Summary: The objective of this study was to evaluate the interaction between plants and nano-Cu under Cu deficiency. Nano-Cu and CuSO4 were applied to Hordeum vulgare L. to examine their effects on plant leaves. The analysis of Cu compounds-plant leaves interactions was conducted using spectroscopic and microscopic methods. The effects of Cu compounds on plant traits were determined after 1 and 7 days of exposure. The results showed that nano-Cu had a lower Cu content compared to CuSO4, and the changes in biochemical traits were mostly observed after 1 day. CuSO4 exposure induced oxidative stress, while nano-Cu at 100 mg L-1 demonstrated enhanced stress tolerance. Overall, nano-Cu showed promising effects on plant health.
ENVIRONMENTAL POLLUTION
(2023)
Article
Agriculture, Multidisciplinary
Huifang Zhao, Yang Liu, Yuqing Huang, Qiyu Liang, Shengguan Cai, Guoping Zhang
Summary: This study used ultraperformance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry technology to investigate the temporal changes of metabolites during malting in different barley varieties and compare the metabolite profiles in kilned malt. The results showed that specific metabolic events occurred during steeping, with Franklin barley variety showing earlier and greater changes. Additionally, there were differences in metabolite composition between malt barley and non-malt barley in the kilned malt samples.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Environmental Sciences
Imen Ayachi, Rim Ghabriche, Ameni ben Zineb, Mohsen Hanana, Chedly Abdelly, Tahar Ghnaya
Summary: The effect of sodium chloride (NaCl) on cadmium (Cd) tolerance, uptake, translocation, and compartmentation in barley was studied. NaCl did not significantly affect plant development and biomass production, but Cd alone reduced plant development rate and biomass production. NaCl addition accentuated the Cd effect on plant growth. NaCl limited Cd accumulation in the roots and shoots by reducing Cd-absorption efficiency and translocation. However, NaCl increased Cd toxicity and limited plant yield.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Applied
Rui Guo, Sen Tian, Xujiao Li, Xuejiao Wu, Xin Liu, Deshun Li, Yanfang Liu, Lianzhong Ai, Zibo Song, Yan Wu
CARBOHYDRATE POLYMERS
(2020)
Review
Pharmacology & Pharmacy
Rui Guo, Xialin Luo, Jingjing Liu, Lian Liu, Xijun Wang, Haitao Lu
PHARMACOLOGICAL RESEARCH
(2020)
Article
Chemistry, Applied
Xujiao Li, Rui Guo, Xuejiao Wu, Xin Liu, Lianzhong Ai, Yi Sheng, Zibo Song, Yan Wu
CARBOHYDRATE POLYMERS
(2020)
Article
Biochemical Research Methods
Jingjing Liu, Xialin Luo, Rui Guo, Wanghui Jing, Haitao Lu
JOURNAL OF PROTEOME RESEARCH
(2020)
Article
Biochemistry & Molecular Biology
Rui Guo, Xujiao Li, Xiangyu Chen, Yuxing Kou, Hao Hu, Xin Liu, Deshun Li, Yanfang Liu, Lianzhong Ai, Zibo Song, Yan Wu
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Chemistry, Analytical
Rui Guo, Xialin Luo, Jingjing Liu, Haitao Lu
Summary: This study identified the regulatory mechanism of iron on biofilm formation in Escherichia coli, as well as new metabolites that directly regulate biofilm formation. This research provides insights into efficiently regulating biofilm formation to tackle harmful impacts in various niches.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Applied
Rui Guo, Xujiao Li, Xianda Ma, Xianbao Sun, Yuxing Kou, Jun'ai Zhang, Deshun Li, Yanfang Liu, Hui Zhang, Yan Wu
Summary: The research revealed that the NSAP-25 aggregates are composed of ellipsoid-like particles of various sizes, forming multi-stranded structures that significantly affect the flexibility and compactness of the random coil chains.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Applied
Xianbao Sun, Xuejiao Wu, Xiangyu Chen, Rui Guo, Yuxing Kou, Xujiao Li, Yi Sheng, Yan Wu
Summary: The study showed that casein-maltodextrin-PAs nanoparticles exhibit good antioxidant activity during storage and under high temperature conditions, prolonging the lifespan of nematodes and protecting them from oxidative stress and heat shock. Additionally, the encapsulation enhanced the bioaccessibility of PAs, suggesting potential applications in novel antioxidants in the nutraceutical industries.
Article
Chemistry, Analytical
Yan Yu, Ziqing Yu, Xufeng Pan, Lei Xu, Rui Guo, Xiaohua Qian, Feng Shen
Summary: Digital PCR is a method that can accurately and precisely quantify target nucleic acids. The use of digital melting curve analysis (digital MCA) allows for the multiplex quantification of multiple target molecules in a single digital PCR. This method uses a self-partitioning SlipChip microfluidic system, which can generate microdroplets with trackable physical positions. The unique melting temperature (T-m) of amplification products can be used as a fingerprint for further classification.
Article
Chemistry, Applied
Rui Guo, Xujiao Li, Xianbao Sun, Yuxing Kou, Jun'ai Zhang, Deshun Li, Yanfang Liu, Taolei Zhao, Hui Zhang, Zibo Song, Yan Wu
Summary: The role of molecular aggregation in tamarind kernel polysaccharides was investigated, and it was found that aggregation had a significant impact on the physicochemical and macromolecular properties of the polysaccharides. These findings suggest the potential applications of molecular aggregation in various fields.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Rui Guo, Jun'ai Zhang, Xin Liu, Xujiao Li, Xianbao Sun, Yuxing Kou, Deshun Li, Yanfang Liu, Hui Zhang, Yan Wu
Summary: In this study, two acidic Biluochun Tea polysaccharides (BTP-A11 and BTP-A12) were compared in terms of their structure and activity, revealing different macromolecular characteristics and radical scavenging activities. This is important for potential applications in the fields of food, medicine, and cosmetics.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Analytical
Tian-Yu Wang, Rui Guo, Long-Long Hu, Jing-Jing Liu, Hai-Tao Lu
Summary: This study investigates the regulatory role of magnesium (Mg2+) in biofilm formation in Escherichia coli (E. coli). The findings reveal that Mg2+ concentration has a significant influence on biofilm formation by regulating phenotypic morphology and triggering metabolic modifications. Metabolomics analysis further identifies differential metabolites and modified metabolic pathways during biofilm formation under different Mg2+ treatments.
JOURNAL OF ANALYSIS AND TESTING
(2022)
Article
Astronomy & Astrophysics
Su-Su Shan, Fan Yang, You-Jun Lu, Xing Wei, Wen-Wu Tian, Hai-Yan Zhang, Rui Guo, Xiao-Hong Cui, Ai-Yuan Yang, Bo Zhang, Ji-Feng Liu
Summary: A precise transit ephemeris is crucial for follow-up exoplanet observations. By comparing TESS Object of Interest (TOI) transit timings with archival ephemeris, it is found that 31 out of 262 hot Jupiters have timing offsets, with WASP-161b showing the largest offset of -203.7 +/- 4.1 minutes. These offsets have a median value of 17.8 minutes, equivalent to 3.6 sigma. Using a self-generated pipeline, TESS timings are generated for these 31 hot Jupiters in each sector, refining and updating the previous ephemeris with a median precision of 0.82 minutes until 2025 and 1.21 minutes until 2030.
ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES
(2023)
Article
Chemistry, Applied
Xianbao Sun, Rui Guo, Yuxing Kou, Hong Song, Taijie Zhan, Jinhong Wu, Lihua Song, Hui Zhang, Fan Xie, Jiangmei Wang, Zibo Song, Yan Wu
Summary: This study found that tamarind seed polysaccharide (TSP) effectively inhibits ice recrystallization. Lowering the molecular weight of TSP enhances its activity and adding TSP to water reduces the melting temperature of ice. Raman spectra indicate that TSP disrupts the hydrogen bond network of water. These findings suggest the potential of TSP as a novel food cryoprotectant and contribute to a better understanding of the antifreeze mechanism of natural polysaccharides.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Analytical
Rui Guo, Haitao Lu
JOURNAL OF ANALYSIS AND TESTING
(2020)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)