Article
Agricultural Engineering
Maria Juliane Suota, Thiago Alessandre da Silva, Sonia Faria Zawadzki, Guilherme Lanzi Sassaki, Fabricio Augusto Hansel, Michael Paleologou, Luiz Pereira Ramos
Summary: This paper provides a detailed characterization of hardwood and softwood kraft lignins obtained from industrial production facilities, focusing on their macromolecular properties and functional groups. LFHL and LFSL both had high lignin contents and low ash and carbohydrate contents. LFHL, with higher methoxyl content and solubility, is suitable for polyurethane foam production, while LFSL could be used for phenolformaldehyde resin replacement and carbon fiber production.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Agricultural Engineering
Ioanna Sapouna, Alexandros Efraim Alexakis, Eva Malmstrom, Lauren Sara McKee
Summary: Renewable resources like wood and its components, such as lignin, have great potential in replacing fossil-based materials. In this study, the impact of lignin structure on the formation of nanoparticles was investigated. The results provide insights into the structure-property relationship of nanoparticles derived from lignin.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Chemistry, Multidisciplinary
Ievgen Pylypchuk, Anastasia Riazanova, Mikael E. Lindstrom, Olena Sevastyanova
Summary: The use of forest lignin as a renewable resource is a greener alternative to the petrochemical industry, advancing the development of environmentally friendly industrial processes. Greater understanding of lignin as a raw material is crucial for creating sustainable value chains. In-depth knowledge of the forces and interactions driving the self-assembly of lignin nanoparticles is required for the development of advanced lignin nanomaterials.
Article
Thermodynamics
Dharmit Nakrani, Mahesh Kumar Tiwari, Tejas Wani, Gaurav Srivastava
Summary: This study proposes an improved two-step combustion model for soft and hard wood based on physical characterization of different wood samples. The kinetic parameters estimated through different estimation methods were utilized to perform computer simulation of cone calorimeter tests. The two-step simulation approach yielded better prediction of heat release rate and time to ignition compared to the one-step simulation approach.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2023)
Article
Biochemistry & Molecular Biology
Yagmur Bas, Linn Berglund, Totte Niittyla, Elisa Zattarin, Daniel Aili, Zeljana Sotra, Ivana Rinklake, Johan Junker, Jonathan Rakar, Kristiina Oksman
Summary: This study demonstrates a straightforward processing route for obtaining nanofibril hydrogels from different wood species for potential use as wound dressings. Softwood shows the best mechanical properties and biocompatibility.
Article
Biochemistry & Molecular Biology
Filipa M. Casimiro, Carina A. E. Costa, Carlos Vega-Aguilar, Alirio E. Rodrigues
Summary: This study evaluated the structural characteristics of lignins obtained from hardwood and softwood sulfite liquors and studied their oxidative depolymerization process. The results showed that lignin could be used as a raw material to produce high-value products such as vanillin and syringaldehyde.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Agricultural Engineering
Ti-Peng Wang, Hang Li, Jiang-Meng Yuan, Wen-Xin Li, Kai Li, Yao-Bing Huang, Ling-Ping Xiao, Qiang Lu
Summary: Pine lignin has the highest G unit content and best thermal stability; bamboo lignin has uniform molecular distribution and a high pCA unit content; poplar lignin contains abundant PB and S units, with phenol as the main pyrolytic product.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Construction & Building Technology
Xin Li, Mahmud Ashraf, Bidur Kafle, Mahbube Subhani
Summary: Increasing concerns about carbon emissions and climate change are driving the adoption of sustainable materials in the construction industry. Engineered timber products, with their renewable characteristics and advancements in lamination techniques and adhesives, are gaining attention in construction. Bond properties play a significant role in these products.
Article
Multidisciplinary Sciences
Chandan Kundu, Shanthi Priya Samudrala, Mahmud Arman Kibria, Sankar Bhattacharya
Summary: The study demonstrates that thermally-assisted peracetic acid pretreatment of lignocellulosic biomass effectively removes lignin with negligible loss of carbohydrates, achieving a 90% delignification rate. It significantly improves biomass digestibility, increasing glucan content, especially when conducted under mild temperature conditions.
SCIENTIFIC REPORTS
(2021)
Article
Materials Science, Paper & Wood
Valeria Stagno, Sara Ricci, Sveva Longo, Elena Verticchio, Francesca Frasca, Anna Maria Siani, Silvia Capuani
Summary: Wood is a hygroscopic material that is affected by moisture, which can be studied using Proton Nuclear Magnetic Resonance (NMR) to understand its behavior. This study aimed to differentiate between softwoods and hardwoods based on NMR relaxation times and found that it is possible to use the relaxation time associated with cell wall bound water as a marker.
Article
Green & Sustainable Science & Technology
Martin Nagl, Oskar Haske-Cornelius, Wolfgang Bauer, Gibson S. Nyanhongo, Georg M. Guebitz
Summary: This study characterized an enzyme formulation rich in endoglucanase, which showed decreased activity above 70 degrees C. The enzyme preparation also contained other enzymatic activities, which resulted in the release of xylose and glucose from pulp. The study found a correlation between enzyme activity and refining performance, indicating that different pulp types may affect enzyme performance.
ENERGY SUSTAINABILITY AND SOCIETY
(2023)
Article
Chemistry, Physical
Hong-Mei Ji, Xiao-Na Liu, Xiao-Wu Li
Summary: The tensile strength and fracture toughness of softwood and hardwood were measured using the Boundary Effect Model (BEM). The experimental results showed that the BEM is a suitable method for estimating the fracture toughness of fibrous and porous woods. In softwood, the variation in the volume percentage of different layers had no noticeable effect on the mechanical properties. In contrast, hardwood exhibited higher tensile strength and fracture toughness due to its complex structure with crossed arrangement of fibers and rays and the presence of large vessels in the fibers. These research findings provide fundamental insights for the design of high-performance bionic materials with a fibrous and porous structure.
Article
Forestry
Luana Giordano, Paolo Gonthier, Francesco Negro, Roberto Zanuttini, Corrado Cremonini
Summary: This study investigated the fungal mould populations on wood packaging materials used in the food industry, and assessed the effectiveness of two new molecules, potassium sorbate and copper-8-quinolinolate, against mould growth. The results showed that both preservatives significantly reduced mould mycelial growth and sporulation on different wooden materials, making them a suitable option for controlling moulds on wood packaging materials.
EUROPEAN JOURNAL OF WOOD AND WOOD PRODUCTS
(2021)
Article
Engineering, Chemical
Xiaokang Xu, Renming Pan, Ruiyu Chen
Summary: The study revealed significant differences in thermal degradation behavior between hardwood and softwood, with hardwood exhibiting a higher reaction rate in the high-temperature region. The dividing points of activation energy decomposition regions were also different for hardwood and softwood, with hardwood having a higher average activation energy than softwood.
Article
Energy & Fuels
Marco Mattonai, Federica Nardella, Luca Zaccaroni, Erika Ribechini
Summary: This study investigated the effects of ball-milling and UV irradiation on softwood and hardwood, using XRD, EGA-MS, and Py-GC/MS. The results showed that UV irradiation can decrease the recalcitrance of biomass towards pyrolysis, but its efficiency depends on the type of lignocellulosic substrate.
Article
Biotechnology & Applied Microbiology
Monika Tolgo, Olav A. Hegnar, Heidi Ostby, Aniko Varnai, Francisco Vilaplana, Vincent G. H. Eijsink, Lisbeth Olsson
Summary: This study provides a detailed functional characterization of six AA9 LPMOs from Thermothielavioides terrestris LPH172. The research shows that these LPMOs have different activities on various cellulose substrates, further supporting the hypothesis that the multiplicity of LPMO genes is related to the complex structure of lignocellulosic biomass.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2022)
Article
Clinical Neurology
Silvia Nitschke, Mitchell A. Sullivan, Sharmistha Mitra, Charlotte R. Marchioni, Jennifer P. Y. Lee, Brandon H. Smith, Saija Ahonen, Jun Wu, Erin E. Chown, Peixiang Wang, Sara Petkovic, Xiaochu Zhao, Laura F. DiGiovanni, Ami M. Perri, Lori Israelian, Tamar R. Grossman, Holly Kordasiewicz, Francisco Vilaplana, Kazuhiro Iwai, Felix Nitschke, Berge A. Minassian
Summary: This study investigates the influence of glucan chain length on precipitation and the disease caused by abnormal glycogen structure. The authors found that the glycogen pathology of RBCK1 deficiency is similar to malin-deficient Lafora disease and can be rescued by downregulating glycogen synthase.
Article
Chemistry, Applied
Hylenne Bojorges, Antonio Martinez-Abad, Marta Martinez-Sanz, Maria Dolores Rodrigo, Francisco Vilaplana, Amparo Lopez-Rubio, Maria Jose Fabra
Summary: The effects of high hydrostatic pressure pre-treatment on the extraction of alginate from different algae species vary, but it can significantly increase the yield of alginate. In addition, the pre-treatment can also affect the M/G values and gelling properties of the extracted alginate.
CARBOHYDRATE POLYMERS
(2023)
Article
Biotechnology & Applied Microbiology
Evgeniy N. N. Donev, Marta Derba-Maceluch, Zakiya Yassin, Madhavi Latha Gandla, Sivan Pramod, Emilia Heinonen, Vikash Kumar, Gerhard Scheepers, Francisco Vilaplana, Ulf Johansson, Magnus Hertzberg, Bjoern Sundberg, Sandra Winestrand, Andreas Hoernberg, Bjoern Alriksson, Leif J. J. Joensson, Ewa J. J. Mellerowicz
Summary: Trees are a promising renewable resource for biorefinery, but their recalcitrance limits their practical use. Large-scale genetic engineering experiments were carried out to reduce recalcitrance in hybrid aspen, resulting in the identification of a construct with improved glucose yield. However, some constructs had negative effects on growth and wood properties. Different traits were associated with high glucose yields in saccharification with and without pretreatment. Genotypes with high glucose yields exhibited increased nanoporosity and altered chemical composition compared to wild-type trees. Pilot-scale pretreatment confirmed the superior sugar yields of the best-performing construct.
PLANT BIOTECHNOLOGY JOURNAL
(2023)
Article
Chemistry, Applied
Loredana Malafronte, Secil Yilmaz-Turan, Leyla Dahl, Francisco Vilaplana, Patricia Lopez-Sanchez
Summary: Whole grain flours are good candidates for natural texturisers in foods and beverages due to their polysaccharides with techno-functional and nutritional properties. However, understanding the relationship between their physicochemical and rheological properties is crucial for developing complex fluids and soft materials using plant components.
FOOD HYDROCOLLOIDS
(2023)
Review
Green & Sustainable Science & Technology
Muhammad Mujtaba, Leonardo Fernandes Fraceto, Mahyar Fazeli, Sritama Mukherjee, Susilaine Maira Savassa, Gerson Araujo de Medeiros, Anderson do Espirito Santo Pereira, Sandro Donnini Mancini, Juha Lipponen, Francisco Vilaplana
Summary: In response to the global warming crisis caused by uncontrolled greenhouse gas production, industries are striving to reduce their dependence on petrochemicals and petroleum-based industrial components and replace them with biobased, sustainable, and environmentally friendly alternatives. Agricultural waste, particularly lignocellulosic biomass, provides a significant resource for the development of various bio-products. Recent advancements in integrated biorefineries have improved the utilization of waste lignocellulose components to produce biofuels, platform chemicals, resins, bioplastics, additives, and other biobased materials for diverse applications.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Food Science & Technology
Daiga Konrade, Sergejs Gaidukovs, Francisco Vilaplana, Pramod Sivan
Summary: Fruit and berry by-products, such as pomace, contain biologically active compounds, especially pectic polysaccharides, which can be extracted and used in various food and pharmaceutical products. This research aims to extract pectin from juice production by-products using a hot water extraction method with weak organic citric acid, minimizing the environmental impact and maximizing the content of bioactive components.
Article
Chemistry, Applied
Reskandi C. Rudjito, Amparo Jimenez-Quero, Maria Del Carmen Casado Munoz, Teun Kuil, Lisbeth Olsson, Mary Ann Stringer, Kristian Bertel Romer Morkeberg Krogh, Jens Eklof, Francisco Vilaplana
Summary: The molecular structure of cereal arabinoxylans (AXs) from wheat and rye influences the activity of different xylanases, resulting in specific profiles of arabinoxylanoligosaccharides (AXOS). The accessibilities of xylanases are influenced by arabinose and ferulic acid substitutions.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Applied
Dongming Zhang, Reskandi C. Rudjito, Solja Pietiainen, Shu-Chieh Chang, Alexander Idstrom, Lars Evenas, Francisco Vilaplana, Amparo Jimenez-Quero
Summary: The intake of dietary fibers is important for human health. Two types of arabinoxylan fibers, one with ferulic acid linked and one without, were produced from wheat bran. The fibers were used in bread production and their interaction with other macromolecules in the bread was investigated. The non-digestability of the fibers was confirmed and they showed potential prebiotic effects during fermentation with probiotic bacteria.
Article
Multidisciplinary Sciences
Shu-Chieh Chang, Mu-Rong Kao, Rebecka Karmakar Saldivar, Sara M. Diaz-Moreno, Xiaohui Xing, Valentina Furlanetto, Johannes Yayo, Christina Divne, Francisco Vilaplana, D. Wade Abbott, Yves S. Y. Hsieh
Summary: (1,3;1,4)-β-D-Glucans are widely distributed in various organisms, but little is known about the enzymes responsible for their synthesis outside the grasses. This study identifies and characterizes the (1,3;1,4)-β-D-glucan synthase RiGT2 in the Gram-positive bacterium Romboutsia ilealis, and demonstrates the production of (1,3;1,4)-β-D-glucans similar to those found in lichens.
NATURE COMMUNICATIONS
(2023)
Article
Plant Sciences
Matthieu Bourdon, Jan J. Lyczakowski, Rosalie Cresswell, Sam Amsbury, Francisco Vilaplana, Marie-Joo Le Guen, Nadege Follain, Raymond Wightman, Chang Su, Fulgencio Alatorre-Cobos, Maximilian Ritter, Aleksandra Liszka, Oliver M. Terrett, Shri Ram Yadav, Anne Vaten, Kaisa Nieminen, Gugan Eswaran, Juan Alonso-Serra, Karin H. Mueller, Dinu Iuga, Pal Csaba Miskolczi, Lothar Kalmbach, Sofia Otero, Ari Pekka Mahonen, Rishikesh Bhalerao, Vincent Bulone, Shawn D. Mansfield, Stefan Hill, Ingo Burgert, Johnny Beaugrand, Yoselin Benitez-Alfonso, Ray Dupree, Paul Dupree, Yka Helariutta
Summary: The introduction of callose through genetic engineering modifies the wood structure and decreases biomass recalcitrance, thus benefiting the economic and technological aspects of biorefinery processes.
Article
Chemistry, Applied
Secil Yilmaz-Turan, Teodora Gal, Patricia Lopez-Sanchez, Mario M. Martinez, Carolin Menzel, Francisco Vilaplana
Summary: This study explores the cascade extraction of polyphenols and pectins from apple pomace and their potential application as food emulsifiers. The extraction of polyphenols was achieved by a simple method using ethanol and resulted in remarkable antioxidant activity. Pectic polysaccharides were sequentially extracted using subcritical water at different temperatures and pH conditions. Acidic pH combined with higher temperature resulted in higher pectin yields, while neutral conditions were less selective towards pectin. The methoxylation of pectin and the relative abundance of different pectic domains could be controlled by subcritical water extraction, which has important implications for the valorization of pectic-rich agricultural wastes into valuable food ingredients.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Multidisciplinary
Pramod Sivan, Emilia Heinonen, Madhavi Latha Gandla, Amparo Jimenez-Quero, Husamettin Deniz Ozeren, Leif J. Jonsson, Ewa J. Mellerowicz, Francisco Vilaplana
Summary: Fast growing hardwoods are important renewable resources for producing bio-based materials, platform chemicals, and biofuels. However, the complex molecular structure of the cell wall components hinders the industrial processing of lignocellulosic biomass. In this study, a hydrothermal step by sequential subcritical water (SW) was implemented to enhance biomass conversion in aspen wood. Subcritical water enabled extraction of non-cellulosic cell wall polysaccharides, improving saccharification yields and promoting the conversion of biomass into fermentable sugars and platform chemicals.
Article
Biotechnology & Applied Microbiology
Monika Tolgo, Olav A. Hegnar, Johan Larsbrink, Francisco Vilaplana, Vincent G. H. Eijsink, Lisbeth Olsson
Summary: This study demonstrates that the xylanolytic activities of two LPMOs depend on the presence of xylan substitutions. The removal of arabinosyl and glucuronoxylan substitutions enhances LPMO activity. This research sheds new light on the activity and interplay of lignocellulolytic enzymes and is important for the development of biomaterials and enzyme cocktails.
BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS
(2023)
Article
Chemistry, Multidisciplinary
Secil Yilmaz-Turan, Kun Jiang, Patricia Lopez-Sanchez, Amparo Jimenez-Quero, Thomas Crouzier, Tomas S. Plivelic, Francisco Vilaplana
Summary: Biocatalytical upgrading of side streams from agricultural biomass into multifunctional materials can increase the circularity of food and material systems. In this study, we designed radical scavenging hydrogels with mechanical integrity and protective effects against reactive oxygen species using enzymatic crosslinking of arabinoxylans (AX) extracted from corn fibre. The influence of two enzymatic systems, laccase/O-2 and peroxidase/H2O2, on the biochemical structure, assembly, properties, and radical scavenging activity of the hydrogels was compared. The results showed that the enzymatic system used for crosslinking affected the network organization and properties of the hydrogels.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
