RadiationGeneSigDB: a database of oxic and hypoxic radiation response gene signatures and their utility in pre-clinical research

Guidelines for using sigQC for systematic evaluation of gene signatures

(2019) Andrew Dhawan et al.   Nature Protocols

Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors

(2018) Andrew Dhawan et al.   Nature Communications

Transcriptomic and genomic profiling of early-stage ovarian carcinomas associated with histotype and overall survival

(2018) Hanna Engqvist et al.   Oncotarget

A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study

(2017) Jacob G Scott et al.   LANCET ONCOLOGY

Subtype-Specific Radiation Response and Therapeutic Effect of FAS Death Receptor Modulation in Human Breast Cancer

(2017) Chen-Ting Lee et al.   RADIATION RESEARCH

Down-regulation of TIMP2 by HIF-1α/miR-210/HIF-3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma

(2016) Alan Ka-Lun Kai et al.   HEPATOLOGY

Comparative analysis of transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma

(2016) Bouchra Tawk et al.   RADIOTHERAPY AND ONCOLOGY

Development and Validation of a Novel Radiosensitivity Signature in Human Breast Cancer

(2015) C. Speers et al.   CLINICAL CANCER RESEARCH

Proteomic Identification of Putative Biomarkers of Radiotherapy Resistance: A Possible Role for the 26S Proteasome?

(2015) Laura Smith et al.   NEOPLASIA

Breast cancer subtypes: response to radiotherapy and potential radiosensitisation

(2013) F E Langlands et al.   BRITISH JOURNAL OF RADIOLOGY

Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer

(2013) M. E. Abazeed et al.   CANCER RESEARCH

A 26-Gene Hypoxia Signature Predicts Benefit from Hypoxia-Modifying Therapy in Laryngeal Cancer but Not Bladder Cancer

(2013) A. Eustace et al.   CLINICAL CANCER RESEARCH

Criteria for the use of omics-based predictors in clinical trials

(2013) Lisa M. McShane et al.   NATURE

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods

(2013) Leif Väremo et al.   NUCLEIC ACIDS RESEARCH

Targeting Hypoxia, HIF-1, and Tumor Glucose Metabolism to Improve Radiotherapy Efficacy

(2012) T. W. H. Meijer et al.   CLINICAL CANCER RESEARCH

A Three-Gene Model to Robustly Identify Breast Cancer Molecular Subtypes

(2012) Benjamin Haibe-Kains et al.   JNCI-Journal of the National Cancer Institute

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer

(2012) Maud H.W. Starmans et al.   RADIOTHERAPY AND ONCOLOGY

Development of a Hypoxia Gene Expression Classifier with Predictive Impact for Hypoxic Modification of Radiotherapy in Head and Neck Cancer

(2011) K. Toustrup et al.   CANCER RESEARCH

Lactate: A Metabolic Key Player in Cancer

(2011) F. Hirschhaeuser et al.   CANCER RESEARCH

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene

(2010) F M Buffa et al.   BRITISH JOURNAL OF CANCER

Generating specificity and diversity in the transcriptional response to hypoxia

(2009) Urban Lendahl et al.   NATURE REVIEWS GENETICS

A Radiation-Derived Gene Expression Signature Predicts Clinical Outcome for Breast Cancer Patients

(2009) Brian D. Piening et al.   RADIATION RESEARCH

Integrating Global Gene Expression and Radiation Survival Parameters across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen

(2008) S. A. Amundson et al.   CANCER RESEARCH