Apatinib in patients with extensive-stage small-cell lung cancer after second-line or third-line chemotherapy: a phase II, single-arm, multicentre, prospective study

Apatinib combined with oral etoposide in patients with platinum-resistant or platinum-refractory ovarian cancer (AEROC): a phase 2, single-arm, prospective study

(2018) Chun-Yan Lan et al.   LANCET ONCOLOGY

First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer

(2018) Leora Horn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-PD-1 Antibody SHR-1210 Combined with Apatinib for Advanced Hepatocellular Carcinoma, Gastric, or Esophagogastric Junction Cancer: An Open-label, Dose Escalation and Expansion Study

(2018) Jianming Xu et al.   CLINICAL CANCER RESEARCH

EGFR‐TKIs plus local therapy demonstrated survival benefit than EGFR‐TKIs alone in EGFR‐mutant NSCLC patients with oligometastatic or oligoprogressive liver metastases

(2018) Tao Jiang et al.   INTERNATIONAL JOURNAL OF CANCER

Apatinib as maintenance therapy in extensive-stage small-cell lung cancer: results from a single-center retrospective study

(2018) Xiangtao Yan et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Real-world treatment patterns and outcomes of patients with small cell lung cancer progressing after 2 lines of therapy

(2018) Anna D. Coutinho et al.   LUNG CANCER

Italian, Multicenter, Phase III, Randomized Study of Cisplatin Plus Etoposide With or Without Bevacizumab as First-Line Treatment in Extensive-Disease Small-Cell Lung Cancer: The GOIRC-AIFA FARM6PMFJM Trial

(2017) Marcello Tiseo et al.   JOURNAL OF CLINICAL ONCOLOGY

Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming

(2017) Lin Tian et al.   NATURE

Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade

(2017) Martina Schmittnaegel et al.   Science Translational Medicine

Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Apatinib in Patients With Chemotherapy-Refractory Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction

(2016) Jin Li et al.   JOURNAL OF CLINICAL ONCOLOGY

Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial

(2016) Scott J Antonia et al.   LANCET ONCOLOGY

Randomized phase II–III study of bevacizumab in combination with chemotherapy in previously untreated extensive small-cell lung cancer: results from the IFCT-0802 trial†

(2015) J.-L. Pujol et al.   ANNALS OF ONCOLOGY

Chemotherapy With or Without Maintenance Sunitinib for Untreated Extensive-Stage Small-Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Phase II Study—CALGB 30504 (Alliance)

(2015) Neal E. Ready et al.   JOURNAL OF CLINICAL ONCOLOGY

Use of thoracic radiotherapy for extensive stage small-cell lung cancer: a phase 3 randomised controlled trial

(2015) Ben J Slotman et al.   LANCET

Topotecan for Relapsed Small-cell Lung Cancer: Systematic Review and Meta-Analysis of 1347 Patients

(2015) Nobuyuki Horita et al.   Scientific Reports

Small cell lung cancer: Where do we go from here?

(2014) Lauren Averett Byers et al.   CANCER

Southwest Oncology Group S0802: A Randomized, Phase II Trial of Weekly Topotecan With and Without Ziv-Aflibercept in Patients With Platinum-Treated Small-Cell Lung Cancer

(2014) Jeffrey W. Allen et al.   JOURNAL OF CLINICAL ONCOLOGY

Relapsed small cell lung cancer: treatment options and latest developments

(2014) Nobuhiro Asai et al.   Therapeutic Advances in Medical Oncology

Treatment of Small Cell Lung Cancer

(2013) James R. Jett et al.   CHEST

Efficacy and Safety of Oral Topotecan and Bevacizumab Combination as Second-Line Treatment for Relapsed Small-Cell Lung Cancer: An Open-Label Multicenter Single-Arm Phase II Study

(2013) David R. Spigel et al.   Clinical Lung Cancer

Third-Line Chemotherapy in Small-Cell Lung Cancer: An International Analysis

(2013) Demetrios Simos et al.   Clinical Lung Cancer

Apatinib for Chemotherapy-Refractory Advanced Metastatic Gastric Cancer: Results From a Randomized, Placebo-Controlled, Parallel-Arm, Phase II Trial

(2013) Jin Li et al.   JOURNAL OF CLINICAL ONCOLOGY

Randomized Phase II Study of Bevacizumab in Combination With Chemotherapy in Previously Untreated Extensive-Stage Small-Cell Lung Cancer: Results From the SALUTE Trial

(2011) David R. Spigel et al.   JOURNAL OF CLINICAL ONCOLOGY

A multicenter international randomized phase III study comparing cisplatin in combination with irinotecan or etoposide in previously untreated small-cell lung cancer patients with extensive disease

(2010) P. Zatloukal et al.   ANNALS OF ONCOLOGY

Prognostic Value of Vascular Endothelial Growth Factor Expression in Patients with Lung Cancer: A Systematic Review with Meta-Analysis

(2010) Ping Zhan et al.   Journal of Thoracic Oncology

Phase II Study of Cisplatin Plus Etoposide and Bevacizumab for Previously Untreated, Extensive-Stage Small-Cell Lung Cancer: Eastern Cooperative Oncology Group Study E3501

(2009) Leora Horn et al.   JOURNAL OF CLINICAL ONCOLOGY

Oral second- and third-line lomustine–etoposide–cyclophosphamide chemotherapy for small cell lung cancer

(2009) Bernard Lebeau et al.   LUNG CANCER