Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers

Role of specialized DNA polymerases in the limitation of replicative stress and DNA damage transmission

(2018) Elodie Bournique et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse

(2018) Anthony Tubbs et al.   CELL

Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition

(2018) Nishita Shastri et al.   MOLECULAR CELL

DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression

(2017) Alexis R. Barr et al.   Nature Communications

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

Retrotransposons as regulators of gene expression

(2016) R. A. Elbarbary et al.   SCIENCE

Lateral Thinking: How Histone Modifications Regulate Gene Expression

(2016) Moyra Lawrence et al.   TRENDS IN GENETICS

Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress

(2016) Megan Chastain et al.   Cell Reports

Transposable Elements in Cancer and Other Human Diseases

(2015) Benoit Chenais   CURRENT CANCER DRUG TARGETS

Role of transposable elements in genomic rearrangement, evolution, gene regulation and epigenetics in primates

(2015) Hee-Eun Lee et al.   GENES & GENETIC SYSTEMS

The chromatin environment shapes DNA replication origin organization and defines origin classes

(2015) Christelle Cayrou et al.   GENOME RESEARCH

Identification of Early Replicating Fragile Sites that Contribute to Genome Instability

(2013) Jacqueline H. Barlow et al.   CELL

Early replication fragile sites: where replication–transcription collisions cause genetic instability

(2013) Oliver Mortusewicz et al.   EMBO JOURNAL

DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis

(2013) Valérie Bergoglio et al.   JOURNAL OF CELL BIOLOGY

Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D

(2013) Xing Lu et al.   Molecular Cancer

Causes and consequences of replication stress

(2013) Michelle K. Zeman et al.   NATURE CELL BIOLOGY

Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

(2013) Nicola Crosetto et al.   NATURE METHODS

Rev3, the catalytic subunit of Polζ, is required for maintaining fragile site stability in human cells

(2013) Audesh Bhat et al.   NUCLEIC ACIDS RESEARCH

RefSeq: an update on mammalian reference sequences

(2013) Kim D. Pruitt et al.   NUCLEIC ACIDS RESEARCH

Common Fragile Site Profiling in Epithelial and Erythroid Cells Reveals that Most Recurrent Cancer Deletions Lie in Fragile Sites Hosting Large Genes

(2013) Benoît Le Tallec et al.   Cell Reports

A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?

(2012) Arkarachai Fungtammasan et al.   GENOME RESEARCH

Mechanism of Replicative DNA Polymerase Delta Pausing and a Potential Role for DNA Polymerase Kappa in Common Fragile Site Replication

(2012) Erin Walsh et al.   JOURNAL OF MOLECULAR BIOLOGY

R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters

(2012) Paul A. Ginno et al.   MOLECULAR CELL

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

The accessible chromatin landscape of the human genome

(2012) Robert E. Thurman et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

R-loop-mediated genomic instability is caused by impairment of replication fork progression

(2011) W. Gan et al.   GENES & DEVELOPMENT

Analysis of protein dynamics at active, stalled, and collapsed replication forks

(2011) B. M. Sirbu et al.   GENES & DEVELOPMENT

Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes

(2011) Anne Helmrich et al.   MOLECULAR CELL

Failure of Origin Activation in Response to Fork Stalling Leads to Chromosomal Instability at Fragile Sites

(2011) Efrat Ozeri-Galai et al.   MOLECULAR CELL

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

(2011) Anne Letessier et al.   NATURE

Molecular profiling of common fragile sites in human fibroblasts

(2011) Benoî Le Tallec et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Common fragile sites: mechanisms of instability revisited

(2011) Michelle Debatisse et al.   TRENDS IN GENETICS

DNA Instability at Chromosomal Fragile Sites in Cancer

(2010) Laura W. Dillon et al.   CURRENT GENOMICS

High-resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome

(2010) Jason S Iacovoni et al.   EMBO JOURNAL

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Systematic identification of fragile sites via genome-wide location analysis of γ-H2AX

(2010) Rachel K Szilard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells

(2010) Ian Hammond-Martel et al.   PLoS One

ATR: a master conductor of cellular responses to DNA replication stress

(2010) Rachel Litman Flynn et al.   TRENDS IN BIOCHEMICAL SCIENCES

Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome

(2010) Robert S. Illingworth et al.   PLoS Genetics

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Common fragile sites are characterized by histone hypoacetylation

(2009) Yanwen Jiang et al.   HUMAN MOLECULAR GENETICS

Human DNA Polymerase   Is Required for Common Fragile Site Stability during Unperturbed DNA Replication

(2009) L. Rey et al.   MOLECULAR AND CELLULAR BIOLOGY

Genomic Study of Replication Initiation in Human Chromosomes Reveals the Influence of Transcription Regulation and Chromatin Structure on Origin Selection

(2009) Neerja Karnani et al.   MOLECULAR BIOLOGY OF THE CELL

The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome

(2009) D. Kumari et al.   NUCLEIC ACIDS RESEARCH

Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

(2009) Joana Sequeira-Mendes et al.   PLoS Genetics

Genome-wide studies highlight indirect links between human replication origins and gene regulation

(2008) J.-C. Cadoret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY