Naturally occurring mixtures of Alternaria toxins: anti-estrogenic and genotoxic effects in vitro

Tracking emerging mycotoxins in food: development of an LC-MS/MS method for free and modified Alternaria toxins

(2018) Hannes Puntscher et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

An integrated in silico/in vitro approach to assess the xenoestrogenic potential of Alternaria mycotoxins and metabolites

(2018) Luca Dellafiora et al.   FOOD CHEMISTRY

Delphinidin protects colon carcinoma cells against the genotoxic effects of the mycotoxin altertoxin II

(2018) Georg Aichinger et al.   TOXICOLOGY LETTERS

Chemotaxonomy of Mycotoxigenic Small-Spored Alternaria Fungi – Do Multitoxin Mixtures Act as an Indicator for Species Differentiation?

(2018) Theresa Zwickel et al.   Frontiers in Microbiology

In vitro characterization of hepatic toxicity of Alternaria toxins

(2018) Stefanie Hessel-Pras et al.   Mycotoxin Research

First insights into Alternaria multi-toxin in vivo metabolism

(2018) Hannes Puntscher et al.   TOXICOLOGY LETTERS

Fluorene-9-bisphenol is anti-oestrogenic and may cause adverse pregnancy outcomes in mice

(2017) Zhaobin Zhang et al.   Nature Communications

Synergistic estrogenic effects of Fusarium and Alternaria mycotoxins in vitro

(2016) Katharina Vejdovszky et al.   ARCHIVES OF TOXICOLOGY

Genistein and delphinidin antagonize the genotoxic effects of the mycotoxin alternariol in human colon carcinoma cells

(2016) Georg Aichinger et al.   MOLECULAR NUTRITION & FOOD RESEARCH

DNA damage and repair kinetics of the Alternaria mycotoxins alternariol, altertoxin II and stemphyltoxin III in cultured cells

(2016) Stefanie C. Fleck et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Impact of Alternaria toxins on CYP1A1 expression in different human tumor cells and relevance for genotoxicity

(2016) G. Pahlke et al.   TOXICOLOGY LETTERS

Spotlight on the Underdogs—An Analysis of Underrepresented Alternaria Mycotoxins Formed Depending on Varying Substrate, Time and Temperature Conditions

(2016) Theresa Zwickel et al.   Toxins

Alternaria in Food: Ecophysiology, Mycotoxin Production and Toxicology

(2015) Hyang Burm Lee et al.   MYCOBIOLOGY

Epoxide Reduction to an Alcohol: A Novel Metabolic Pathway for Perylene Quinone-Type Alternaria Mycotoxins in Mammalian Cells

(2014) Stefanie C. Fleck et al.   CHEMICAL RESEARCH IN TOXICOLOGY

An in vitro investigation of endocrine disrupting effects of the mycotoxin alternariol

(2013) Caroline Frizzell et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Role of topoisomerase inhibition and DNA repair mechanisms in the genotoxicity of alternariol and altertoxin-II

(2013) C. Tiessen et al.   World Mycotoxin Journal

Characterization of a genotoxic impact compound in Alternaria alternata infested rice as Altertoxin II

(2012) Christoph Schwarz et al.   ARCHIVES OF TOXICOLOGY

Minor contribution of alternariol, alternariol monomethyl ether and tenuazonic acid to the genotoxic properties of extracts from Alternaria alternata infested rice

(2012) Christoph Schwarz et al.   TOXICOLOGY LETTERS

Modulation of the cellular redox status by the Alternaria toxins alternariol and alternariol monomethyl ether

(2012) Christine Tiessen et al.   TOXICOLOGY LETTERS

The Alternaria mycotoxins alternariol and alternariol methyl ether induce cytochrome P450 1A1 and apoptosis in murine hepatoma cells dependent on the aryl hydrocarbon receptor

(2011) Ilona Schreck et al.   ARCHIVES OF TOXICOLOGY

Repair of DNA damage induced by the mycotoxin alternariol involves tyrosyl-DNA phosphodiesterase 1

(2010) Markus Fehr et al.   Mycotoxin Research

AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions

(2008) Fumiaki Ohtake et al.   BIOCHEMICAL PHARMACOLOGY

Alternariol acts as a topoisomerase poison, preferentially affecting the IIα isoform

(2008) Markus Fehr et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols