期刊
ANNALS OF EMERGENCY MEDICINE
卷 75, 期 2, 页码 287-298出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.annemergmed.2019.06.027
关键词
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资金
- National Foundation of Emergency Medicine
The role of lactic acid and its conjugate base, lactate, has evolved during the past decade in the care of patients in the emergency department (ED). A recent national sepsis quality measure has led to increased use of serum lactate in the ED, but many causes for hyperlactatemia exist outside of sepsis. We provide a review of the biology of lactate production and metabolism, the many causes of hyperlactatemia, and evidence on its use as a marker in prognosis and resuscitation. Additionally, we review the evolving role of lactate in sepsis care. We provide recommendations to aid lactate interpretation in the ED and highlight areas for future research.
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