Article
Agriculture, Multidisciplinary
Wei Lan, Chengying Hai, Qiong Shi, Shuo Wang, Gaoqiong Deng, Hengye Chen, Youyou Wang, Jian Yang, Haiyan Fu
Summary: In this study, an inner filter effect-based fluorescence probe was developed for the rapid detection of ascorbic acid (AA). The probe consisting of nitrogen-doped carbon dots (NCDs) and cobalt oxyhydroxide nanoflakes (CoOOH NFs) showed a specific redox reaction with AA leading to the recovery of fluorescence. The probe demonstrated a linear relationship between the recovered fluorescence intensities and AA concentrations, and it has potential applications in both food and clinical testing.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Chemistry, Inorganic & Nuclear
Xucan Yuan, Yi Sun, Pengfei Zhao, Longshan Zhao, Zhili Xiong
Summary: A target-dependent ratiometric fluorescence sensing strategy was designed for highly sensitive detection of alpha-glucosidase (alpha-Glu) activity and its inhibitor, utilizing SiQDs and CoOOH nanosheets. The method achieved ratiometric detection based on dual-fluorescence signal responses, showing great application potential.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Applied
Pei Jia, Jiayu Yang, Jinjie Hou, Kairong Yang, Taotao Zhe, Tong Bu, Li Wang
Summary: A new ratiometric platform for sensing Hg2+ was developed which combined fluorescence and scattering signals. The ratiometric strategy exhibited superior performance in detecting Hg2+ by utilizing two independent signals.
Article
Materials Science, Multidisciplinary
Li Chen, Limin Zheng, Fangqi Wang, Simin Yi, Donghao Liu, Xinzhi Huang, Rong Chen, Hua He
Summary: In this study, a dual-emission sensor was developed for sensing ascorbic acid (AA) using CdTe quantum dots and Zr-MOF. The sensor showed good sensitivity towards AA and great selectivity over other structural analogs, benefiting from the confinement effect of the UiO-66-NH2 host.
Article
Chemistry, Analytical
Ning Li, Feng Zhang, Wenying Sun, Lili Zhang, Xingguang Su
Summary: In this study, a sensitive fluorescence biosensor based on fluorescence resonance energy transfer (FRET) between MoS2 quantum dots (MQDs) and CoOOH nanoflakes was developed for the assay of ascorbic acid oxidase (AAO). Under optimal experimental conditions, the developed fluorescence method exhibited good linear ranges and low detection limits for AAO detection. The proposed biosensor showed high sensitivity and selectivity, and was successfully applied for AAO determination in human serum samples.
Article
Chemistry, Analytical
Zhiwen Gan, Tian Zhang, Yongmei Hu, Shujun Zhen, Xiaoli Hu
Summary: Developing ratiometric fluorescence probes for biothiols is of great significance. A simple ratiometric sensor for biothiols was developed based on CdTe quantum dots, which exhibited enhanced fluorescence and quenched second-order scattering in the presence of biothiols. The sensor showed fast response, simplicity, high sensitivity, and strong specificity, making it suitable for the quantification of biothiols in real samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Spectroscopy
Qian Tang, Zhe Sun, Min Qing, Lei Wang, Yu Ling, Nian Bing Li, Hong Qun Luo
Summary: An optical sensor utilizing CDs and MnO2 nanosheets was developed for sensitive detection of H2O2 and glucose. By combining ratiometric and turn-off dual modes, the sensor achieved accurate detection of H2O2 and provided a new idea for the study of the combination of scattering and fluorescence. The sensor showed great potential for practical applications in the field of biosensing.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Haijuan Zhang, Yangxia Han, Yali Yang, Jia Chen, Hongdeng Qiu
Summary: A fluorescence platform for monitoring acid phosphatase (ACP) levels was established by assembling red emitting carbon dots (RCDs) on cobalt oxyhydroxide (CoOOH) nanoflakes. The fluorescence of the RCDs could be quenched by the nanoflakes, but was recovered by the reduction of CoOOH nanoflakes catalyzed by ACP. The biosensor showed rapid, sensitive, and selective detection of ACP with a low detection limit.
Article
Chemistry, Physical
Xiaolin Tian, Zhefeng Fan
Summary: A ratiometric fluorescence sensor based on the self-assembly of Eu3+ and CDs was developed for the direct detection of AA. The sensor showed excellent sensitivity and selectivity, and demonstrated great potential for the determination of AA in food samples.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2021)
Article
Spectroscopy
Ning Wu, Hao Guo, Mingyue Wang, Liping Peng, Yuan Chen, Bingqing Liu, Zhilan Pan, Yinsheng Liu, Wu Yang
Summary: This research presents a new ratiometric detection method by using MIL-68(In)-NH2 as both the fluorescence element and the scattered light unit. The method combines fluorescence and scattering to construct a fluorescence and scattered light ratio system. The method shows good performance in detecting Hg2+ and has been successfully applied to the evaluation of Hg2+ in actual water samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Bo Peng, Yang Guo, Yongjun Ma, Min Zhou, Youquan Zhao, Jingfeng Wang, Yanjun Fang
Summary: A multi-mode detection platform based on cobalt oxyhydroxide nanoflakes was designed for ascorbic acid (AA) detection, enabling rapid and accurate measurement of AA content with the advantages of simplicity, portability, speed, and low cost.
MICROCHEMICAL JOURNAL
(2022)
Article
Spectroscopy
Xiaoping Chen, Jianwei Lin, Yafeng Zhuang, Siqi Huang, Jinghua Chen, Zhizhong Han
Summary: A new ratiometric fluorescence sensor is developed for the selective detection of chlorotetracycline (CTC) using dual-mode fluorescence method, demonstrating good selectivity and sensitivity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biochemical Research Methods
Bing Jie Wang, Zi Yi Xu, Zhe Sun, Zi Qing Li, Yuan Hao Luo, Hong Qun Luo, Nian Bing Li
Summary: In this work, a composite probe (CDs@ZIF-90) based on carbon dots (CDs) and zeolitic imidazolate framework-90 (ZIF-90) is constructed to ratiometrically detect bisulfite (HSO3-) and sulfite (SO32-). The proposed strategy shows a broad linear range (10 μM to 8.5 mM) and a low limit of detection (2.74 μM) for HSO3-/SO32- determination. The strategy is successfully applied for evaluating HSO3-/SO32- in sugar with satisfactory recoveries.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Automation & Control Systems
Ming-Yue Dong, Hai-Long Wu, Tong Wang, Kun Huang, Ru-Qin Yu
Summary: This paper proposes two second-order calibration algorithms, TDR-ATLD and TDR-SWATLD, for directly decomposing three-way fluorescence data with scattering regions removed. The algorithms show better performance in dealing with fluorescence data with scattering compared to other algorithms. TDR-ATLD has faster convergence and greater potential in processing fluorescence data with scattering.
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
(2023)
Article
Chemistry, Inorganic & Nuclear
Gregory D. Sutton, Chenggang Jiang, Gardenia Liu, Thomas S. Teets
Summary: This article presents four luminescent ratiometric oxygen sensors, which combine phosphorescent cyclometalated iridium with coumarin or BODIPY fluorophores. These compounds improve previous designs with higher phosphorescence quantum yields, better suitability for atmospheric O-2 levels, and the use of visible excitation instead of UV. The sensors are synthesized through simple 1-step reactions between the chloro-bridged cyclometalated iridium dimer and the pyridyl-substituted fluorophore. They exhibit phosphorescent quantum yields up to 29% and varying phosphorescence lifetimes, with one sensor being highly responsive to oxygen. One sensor also achieves dual emission through visible excitation at 430 nm.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)