Review
Chemistry, Analytical
Xiaoping Wang, Hui Li, Kaijun Quan, Liang Zhao, Hongdeng Qiu, Zuguang Li
Summary: Separation and identification of chiral enantiomers are increasingly important in various fields like pharmaceutical production, chemical intermediates preparation, and biochemistry. Cellulose and its derivatives, with strong chiral recognition ability, large loading capacity and ease of functionalization, have shown excellent performance in enantioseparation, indicating great potential in chiral separation. This review systematically summarizes the types of cellulose derivatives, preparation of cellulose-functionalized chiral stationary phases, and their recent applications in chiral chromatographic separation, aiming to provide a useful reference for researchers and inspire new discoveries in the field.
Article
Polymer Science
Geng Li, Xiao Dai, Yixuan Min, Lili Zhang, Shihui Han, Jun Shen, Yoshio Okamoto
Summary: The research investigates the enantioseparation performance of hybrid bead-type CSPs with higher organic content, revealing their stronger enantioseparation power compared to those with lower organic content and previous analogous CSPs. The hybrid CSPs also exhibit higher enantioselectivity than Chiralpak IB, a popular commercialized CSP. Furthermore, the higher loading capacity of the hybrid CSPs is beneficial for efficient enantioseparation, especially for preparative purposes.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Biochemical Research Methods
Bao Tan Nguyen, Yoon Jung Choi, Kyeong Ho Kim, Gyu Yong Song, Hyung Min Kim, Jong Seong Kang
Summary: Plant-based bioactive substances are commonly used to treat inflammation due to their low toxicity and cost-effectiveness. This study developed a simple and effective method for chiral separation of decursinol and its derivatives, which have anti-cancer and anti-inflammatory properties. By using different polysaccharide-based chiral stationary phases (CSPs) and alcohol modifiers, the researchers achieved baseline separation and compared the chiral separation abilities of each column. Molecular docking simulations were conducted to understand the chiral recognition mechanism, and the results showed that hydrogen bonds, π-π interactions, and hydrophobic interactions played important roles. Overall, this study has practical implications for optimizing chiral separation techniques in the pharmaceutical and clinical industries.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Chemistry, Analytical
Ying Wang, Ji-Kai Chen, Ling-Xiao Xiong, Bang-Jin Wang, Sheng-Ming Xie, Jun-Hui Zhang, Li-Ming Yuan
Summary: This study demonstrates the first immobilization of a chiral porous organic cage on thiol-functionalized silica to prepare novel chiral stationary phases for high-performance liquid chromatography. The prepared CSPs exhibited excellent enantioselectivity for the resolution of various racemates. The importance of the cationic imidazolium spacer for chiral separation was also demonstrated. The chiral POCs showed good chiral recognition complementarity with the two most popular commercial chiral columns.
ANALYTICAL CHEMISTRY
(2022)
Review
Polymer Science
Guanzhao Wu
Summary: Chiral separation by HPLC using a CSP is a reliable method for obtaining pure enantiomers. Helical polyacetylene derivatives show excellent chiral recognition abilities and are promising CSP candidates for HPLC. This review discusses the development of helical polyacetylene derivatives with different chiral pendants and their potential as coated CSPs for enantioseparation in HPLC.
Review
Biochemical Research Methods
Huifeng Liu, Zhihai Wu, Jia Chen, Jianhua Wang, Hongdeng Qiu
Summary: Chirality is a common phenomenon in nature and the separation of chiral drugs is crucial for their safe utilization. High-performance liquid chromatography (HPLC) is an effective tool for compound separation and analysis, with chromatographic packing playing a key role. Chiral pharmaceutical separation and analysis in HPLC rely on chiral stationary phases (CSPs), thus various CSPs are being developed to meet the needs of chiral drug separation and analysis.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Chemistry, Multidisciplinary
Geng Li, Xiao Dai, Yixuan Min, Lili Zhang, Jun Shen, Yoshio Okamoto
Summary: Four hybrid bead-type CSPs with organic contents higher than 20% were developed using a modified Stober process in basic conditions, showing better enantioseparation properties than previous analogues. These hybrid CSPs exhibited higher enantioselectivity than the commercial Chiralpak IB in some cases.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Materials Science, Paper & Wood
Cuong Viet Bui, Thomas Rosenau, Hubert Hettegger
Summary: Regioselective tritylation and carbonate aminolysis were used to synthesize cellulose 2,3-bis(3,5-dimethylphenyl carbamate)-6-(alpha-phenylethyl carbamate)-type chiral selectors. The critical aspects of regioselective tritylation and detritylation at C6 of the glucopyranose units were evaluated and optimized. Oxycarbonylation and aminolysis reactions were employed to introduce reactive moieties and convert intermediates. Comprehensive analytical techniques were used to characterize the starting material, intermediates, and target cellulose derivatives. The optimized protocol allowed for the synthesis of cellulose carbamate-type chiral selectors using simple primary amines, achieving enantioseparation performance comparable to a reference selector. Rating: 7/10
Review
Chemistry, Medicinal
Jun Haginaka
Summary: This review article focuses on the preparation, chiral recognition properties, and mechanisms of chiral stationary phases (CSPs) based on proteins and glycoproteins, with a particular emphasis on our group's investigations. The proteins and glycoproteins studied include bovine serum albumin, human serum albumin, lysozyme, pepsin, human alpha(1)-acid glycoprotein (AGP), chicken ovomucoid, and chicken ovoglycoprotein (chicken AGP).
CHEMICAL & PHARMACEUTICAL BULLETIN
(2022)
Article
Biochemical Research Methods
Eliana A. Agathokleous, Ioannis J. Stavrou, Constantina Kapnissi-Christodoulou
Summary: In this study, various types of chiral stationary phases were utilized for the chiral separations of different clinically and pharmaceutically important compounds in high-performance liquid chromatography. It was found that RN-CF6 was the most suitable and efficient chiral stationary phase for separating a wide range of analytes, including acids, amines, alcohols, and neutral compounds, providing baseline enantioseparation for thyroxine and cetirizine.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Medicinal
David Jin Han Seog, Nguyen van Kien, Jae Jeong Ryoo
Summary: This updated minireview focuses on chiral stationary phases (CSPs) based on amino alcohols. The study highlights the use of amino alcohols as starting materials for the preparation of chiral catalysts in asymmetric organic synthesis and CSPs for chiral separations. Important developments and applications of various CSPs, including Pirkle-type CSPs, ligand exchange CSPs, alpha-amino acid-derived amino alcohol CSPs, and symmetric CSPs, are summarized to propose ideas for developing new CSPs with improved performance.
Article
Biochemical Research Methods
Yuanyuan Pei, Xinyu Li, Guangjian Zeng, Yuting Gao, Tao Wen
Summary: Two novel chiral stationary phases (CSPs) based on lactide derivatives, PMLA and N-PMLA, showed better chiral recognition ability compared to PLLA in both reversed-phase and normal-phase chromatographic modes in this study.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Chemistry, Medicinal
Zhengyue Ma, Panpan Shang, Delu Liu, Yangyang Nie, Yanli Liu, Xinyuan Guo, Benben Wei, Ligai Bai, Xiaoqiang Qiao
Summary: This study developed three new chiral stationary phases based on silica modified with peptides containing phenylalanine and proline. Successful analyses and characterizations were conducted using Fourier transform infrared spectra, elemental analysis, and thermogravimetric analysis. The enantioselective performance of the three chiral peptide-based columns was evaluated using 11 racemic compounds, and optimized enantiomeric separation conditions were established. The results showed that the CSP-1 column had good reproducibility (RSD = 0.73%, n = 5) and successfully separated the enantiomers of flurbiprofen and naproxen.
Article
Chemistry, Analytical
Yu Xu, Ang Li, Song Xue, Sihui Ding, Qi Zhang
Summary: This study demonstrates the use of hydrophobic deep eutectic solvents (HDESs) in capillary electrophoresis (CE) for chiral separations. The HDES N8881Cl:OctA can form nano-sized microdroplets in CE background electrolyte solutions and acts as a new type of pseudo-stationary phase (PSP) exhibiting hydrophobic effects. The presence of N8881Cl:OctA significantly improves the enantioresolutions of model drugs with various cyclodextrin (CD)-type chiral selectors, and the migration time of enantiomers can be reduced using an anionic CD.
Article
Biochemical Research Methods
Chunqiang Liu, Kaijun Quan, Jia Chen, Xiaofeng Shi, Hongdeng Qiu
Summary: Chiral metal organic frameworks (CMOFs), with customizable combination of metal nodes and organic ligands, have attracted increasing attention due to their highly ordered crystal structure and rich adjustable chiral structure. This review discusses the progress of CMOFs and their different types of composites used as chiral stationary phases (CSPs) in liquid chromatography for enantioseparation. The characteristics of CMOFs and their composites are summarized, aiming to provide new ideas for the development of CMOFs with better performance and further promote the application of CMOFs materials in enantioselective high-performance liquid chromatography (HPLC).
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Chemistry, Multidisciplinary
Kunfeng Jin, Jinming Zhang, Weiguo Tian, Xin Ji, Jian Yu, Jun Zhang
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2020)
Article
Polymer Science
Yaohui Cheng, Xin Zhang, Chunchun Yin, Jinming Zhang, Jian Yu, Jun Zhang
Summary: The study introduces new cellulose esters containing imidazolium cation for enhanced CO2 gas separation. These materials effectively improve the CO2 permeability of cellulose ester/ILs composite membranes, showing good mechanical properties and thermal stability.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Engineering, Chemical
Hongchao Lu, Zhenghao Xia, Qinyong Mi, Jinming Zhang, Xuejing Zheng, Zhiyuan He, Jin Wu, Jun Zhang
Summary: In this paper, eco-friendly and multifunctional cellulose/MWCNT composite films with superhigh Joule heating performance, outstanding electromagnetic interference shielding efficiency, high electrical conductivity, and good mechanical properties are developed using a simple paper-making process and an ionic liquid as the solvent of cellulose.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Rumeng Xu, Chunchun Yin, Jinming Zhang, Yan Zhou, Qinyong Mi, Jun Zhang
Summary: Cellulose acetate (CA) is a commercially used material with excellent properties, but it is nonbiodegradable due to its hydrophobicity and poor adhesion to microbes. This study demonstrates a simple and mild treatment method to trigger the biodegradability and green-reuse of CA materials, by immersing them into common salt aqueous solutions. The treated CA materials showed improved hydrophilicity and adhesion to microbes, leading to rapid degradation in composting and soil burial tests. The method has great potential in environmental protection and ecofriendly utilization of biomass resources.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Multidisciplinary Sciences
Yan Zhou, Jinming Zhang, Yaohui Cheng, Xin Zhang, Jin Wu, Jun Zhang
Summary: A revolutionary potential in polysaccharide chemistry industries is demonstrated by a super-rapid and highly efficient modification strategy using imidazolium-based ionic liquids and click esterification method, which allows for rapid and efficient modification of various polysaccharides under catalyst-free conditions.
Article
Nanoscience & Nanotechnology
Xin Zhang, Yaohui Cheng, Jingxuan You, Jinming Zhang, Yirong Wang, Jun Zhang
Summary: The article describes the development of a new type of biopolymer-based phosphorescent materials that have excellent processability and irreversible humidity-responsiveness by introducing the imidazolium cation to the cellulose chain.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Yan Zhou, Yaohui Cheng, Qinyong Mi, Xiaocheng Zhang, Jinming Zhang, Jun Zhang
Summary: In this study, two new methods using BmimAc ionic liquid as an additive were proposed to accurately and rapidly measure the molecular weight parameters of cellulose. These methods have advantages such as wide applicable range, simple preparation process, high accuracy, and fast detection, overcoming the existing problems in traditional methods.
ANALYTICAL CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Xin Zhang, Yaohui Cheng, Jingxuan You, Jinming Zhang, Chunchun Yin, Jun Zhang
Summary: In this study, a processable phosphorescent cationized cellulose derivative was developed by introducing ionic structures into cellulose chains. The resulting material exhibited excellent antibacterial properties, water resistance, and environmental friendliness, making it a promising candidate for advanced anti-counterfeiting, information encryption, and other applications.
NATURE COMMUNICATIONS
(2022)
Article
Polymer Science
Ming-Xuan Du, Ya-Fei Yuan, Jin-Ming Zhang, Chen-Yang Liu
Summary: The solubility of polymers in ionic liquids is mainly determined by hydrogen bonding interactions. The excess interaction parameter chi(HB), which accounts for the difference in hydrogen-bonding parameters between the polymer and solvent, provides a significant correction in the Flory-Huggins theory. This finding offers a new screening tool for the solubility of polar polymers, in addition to the like dissolves like principle.
Article
Chemistry, Multidisciplinary
Yirong Wang, Yaohui Cheng, Chunchun Yin, Jinming Zhang, Xin Zhang, Jun Zhang
Summary: The authors constructed an environmentally friendly coating with switchable aqueous processability, complete biodegradability, intrinsic flame retardance, and high transparency by using natural biomass and montmorillonite. The coating exhibited a low peak heat release rate and formed a porous structure to effectively protect combustible materials from fire. Additionally, the coating had high transparency, was water-soluble and completely degradable.
Article
Chemistry, Multidisciplinary
Zhenghao Xia, Hongchao Lu, Guangmei Xia, Jinming Zhang, Yan Zhou, Qinyong Mi, Jinyang Li, Jun Zhang
Summary: We have developed a simple and efficient method to process agricultural and forestry biomass into high-tough all-biomass materials by creating hydrogen-bonding networks. This method significantly improves the formability and toughness of biomass materials, which are commonly limited in their application due to poor formability and low toughness. By combining a paper-making process with in situ welding, a regenerated cellulose material with layered microstructure is formed, allowing energy dissipation during stretching and resulting in tough and strong cellulose plastics. This scalable process has the potential to transform various agricultural and forestry wastes into eco-friendly materials, contributing to environmental protection and bioresource utilization.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Multidisciplinary Sciences
Jingxuan You, Xin Zhang, Qinying Nan, Kunfeng Jin, Jinming Zhang, Yirong Wang, Chunchun Yin, Zhiyong Yang, Jun Zhang
Summary: The authors have developed room temperature phosphorescent (RTP) materials with different emission modes by regulating the aggregation state. These materials have potential in various applications due to their multiple emission and excitation modes.
NATURE COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Xiang Li, Xiaoqian Ji, Guangmei Xia, Xingxiang Ji, Jinming Zhang, Jun Zhang, Fengshan Zhang, Haq Nawaz
Summary: This study provides a new method for large-scale production of ANF films, and ANF films with high transparency, anti-ultraviolet capacity, and tunable haze can be fabricated by adjusting the composition of the coagulation bath. ANF films regenerated from water exhibit the highest transmittance and tensile strength, while ethanol-treated ANF films have the highest haze.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Yan Zhou, Xiaocheng Zhang, Dongxiao Yin, Jinming Zhang, Qinyong Mi, Hongchao Lu, Dehai Liang, Jun Zhang
Summary: This paper reveals the influence of ionic liquids and co-solvents on the cellulose solution state and formation mechanism, and identifies the hydrogen-bonding basicity and microstructure as the key factors determining the cellulose dissolution process.
Article
Chemistry, Physical
Ya-Fei Yuan, Jin-Ming Zhang, Bao-Qing Zhang, Jia-Jian Liu, Yan Zhou, Ming-Xuan Du, Lin-Xue Han, Kuang-Jie Xu, Xin Qiao, Chen-Yang Liu
Summary: Polymer solubility in ionic liquids cannot be predicted by traditional solubility parameter approach. ILs can be classified based on their hydrogen-bond acidity or basicity, with acidic ILs dissolving basic polymers and basic ILs dissolving acidic polymers. A quantitative hydrogen-bonding analysis has been proposed to predict solubility, validated by experimental data of 19 polymers in 11 ILs. These principles can be applied to other systems governed by hydrogen bonding.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)