期刊
AMERICAN JOURNAL OF EPIDEMIOLOGY
卷 189, 期 4, 页码 343-353出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/aje/kwz209
关键词
cohort studies; depression; mental health; meta-analysis; multicenter studies; residence characteristics
资金
- European Union [676060]
- Swiss National Centre of Competence in Research LIVES-Overcoming Vulnerability: Life Course Perspectives - Swiss National Science Foundation [51NF40-160590]
- US National Institute of Aging
- consortium of United Kingdom government departments
- US National Institute on Aging [U01AG009740, U01_AG09740-13S2, P01_AG005842, P01_AG08291, P30_AG12815, R21_AG025169, Y1-AG-4553-01, IAG_BSR06-11, OGHA_04-064, HHSN271201300071C]
- European Commission [QLK6-CT-2001-00360, RII-CT-2006-062193, CIT5-CT-2005-028857, CIT4-CT-2006-028812, GA 211909, GA 227822, GA 261982, GA 676536, GA 654221]
- European Commission's Directorate-General for Employment, Social Affairs and Inclusion
- German Ministry of Education and Research
- Max Planck Society for the Advancement of Science
- ESRC [ES/R008264/1] Funding Source: UKRI
Although residential environment might be an important predictor of depression among older adults, systematic reviews point to a lack of longitudinal investigations, and the generalizability of the findings is limited to a few countries. We used longitudinal data collected between 2012 and 2017 in 3 surveys including 15 European countries and the United States and comprising 32,531 adults aged 50 years or older. The risk of depression according to perceived neighborhood disorder and lack of social cohesion was estimated using 2-stage individual-participant-data meta-analysis; country-specific parameters were analyzed by meta-regression. We conducted additional analyses on retired individuals. Neighborhood disorder (odds ratio (OR) = 1.25) and lack of social cohesion (OR = 1.76) were significantly associated with depression in the fully adjusted models. In retirement, the risk of depression was even higher (neighborhood disorder: OR = 1.35; lack of social cohesion: OR = 1.93). Heterogeneity across countries was low and was significantly reduced by the addition of country-level data on income inequality and population density. Perceived neighborhood problems increased the overall risk of depression among adults aged 50 years or older. Policies, especially in countries with stronger links between neighborhood and depression, should focus on improving the physical environment and supporting social ties in communities, which can reduce depression and contribute to healthy aging.
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