Current concepts in the treatment of hereditary ataxias

Cycling Regimen Induces Spinal Circuitry Plasticity and Improves Leg Muscle Coordination in Individuals With Spinocerebellar Ataxia

(2015) Ya-Ju Chang et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Primary and secondary ataxias

(2015) Hélio A.G. Teive et al.   CURRENT OPINION IN NEUROLOGY

Planning future clinical trials in Machado Joseph disease: Lessons from a phase 2 trial

(2015) Jonas Alex Morales Saute et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Riluzole in patients with hereditary cerebellar ataxia: a randomised, double-blind, placebo-controlled trial

(2015) Silvia Romano et al.   LANCET NEUROLOGY

Treatable causes of cerebellar ataxia

(2015) Adolfo Ramirez-Zamora et al.   MOVEMENT DISORDERS

Milestones in Friedreich ataxia: more than a century and still learning

(2015) Agessandro Abrahão et al.   NEUROGENETICS

Long-term improvement of tremor and ataxia after bilateral DBS of VOP/zona incerta in FXTAS

(2015) M. G. dos Santos Ghilardi et al.   NEUROLOGY

Epigenetic therapy for Friedreich ataxia

(2014) Elisabetta Soragni et al.   ANNALS OF NEUROLOGY

Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study

(2014) Vincenzo Libri et al.   LANCET

A randomized, phase 2 clinical trial of lithium carbonate in Machado-Joseph disease

(2014) Jonas Alex Morales Saute et al.   MOVEMENT DISORDERS

Preimplantation genetic diagnosis for inherited neurological disorders

(2014) Ilan Tur-Kaspa et al.   Nature Reviews Neurology

Memantine Effects on Verbal Memory in Fragile X-associated Tremor/Ataxia Syndrome (FXTAS): a Double-Blind Brain Potential Study

(2014) Jin-Chen Yang et al.   NEUROPSYCHOPHARMACOLOGY

Motor Training in Degenerative Spinocerebellar Disease: Ataxia-Specific Improvements by Intensive Physiotherapy and Exergames

(2014) Matthis Synofzik et al.   Biomed Research International

Patients with autosomal dominant spinocerebellar ataxia have more risk of falls, important balance impairment, and decreased ability to function

(2013) Carolina Yuri P. Aizawa et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Speech in spinocerebellar ataxia

(2013) Ellika Schalling et al.   BRAIN AND LANGUAGE

Consensus Paper: Management of Degenerative Cerebellar Disorders

(2013) W. Ilg et al.   CEREBELLUM

Cerebrotendinous xanthomatosis

(2013) Ingemar Björkhem   CURRENT OPINION IN LIPIDOLOGY

Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3

(2013) P. K. Chan et al.   HUMAN MOLECULAR GENETICS

The effectiveness of allied health care in patients with ataxia: a systematic review

(2013) Ella M. R. Fonteyn et al.   JOURNAL OF NEUROLOGY

Niemann-Pick disease type C symptomatology: an expert-based clinical description

(2013) Eugen Mengel et al.   Orphanet Journal of Rare Diseases

Silencing Mutant Ataxin-3 Rescues Motor Deficits and Neuropathology in Machado-Joseph Disease Transgenic Mice

(2013) Clévio Nóbrega et al.   PLoS One

We Cannot Cure Ataxia, We Can Only Eradicate It

(2013) Khalaf Bushara   JAMA Neurology

Heterogeneity of Coenzyme Q10Deficiency

(2012) Valentina Emmanuele et al.   ARCHIVES OF NEUROLOGY

Retrospective Study of the Effects of Inpatient Rehabilitation on Improving and Maintaining Functional Independence in People With Friedreich Ataxia

(2012) Sarah C. Milne et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Recommendations for the diagnosis and management of Niemann–Pick disease type C: An update

(2012) Marc C. Patterson et al.   MOLECULAR GENETICS AND METABOLISM

A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3

(2012) T. A. Zesiewicz et al.   NEUROLOGY

The Autosomal Recessive Cerebellar Ataxias

(2012) Mathieu Anheim et al.   NEW ENGLAND JOURNAL OF MEDICINE

The videofluoroscopic swallowing study shows a sustained improvement of dysphagia in children with Niemann-Pick disease type C after therapy with miglustat

(2011) Simona Fecarotta et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Sleep disorders in cerebellar ataxias

(2011) José L. Pedroso et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Primary and secondary CoQ10 deficiencies in humans

(2011) Catarina M. Quinzii et al.   BIOFACTORS

Oral Zinc Sulphate Supplementation for Six Months in SCA2 Patients: A Randomized, Double-Blind, Placebo-Controlled Trial

(2011) Luis Velázquez-Pérez et al.   NEUROCHEMICAL RESEARCH

A randomized trial of 4-aminopyridine in EA2 and related familial episodic ataxias

(2011) M. Strupp et al.   NEUROLOGY

X-linked disorders with cerebellar dysgenesis

(2011) Ginevra Zanni et al.   Orphanet Journal of Rare Diseases

Glucose transporter-1 deficiency syndrome: the expanding clinical and genetic spectrum of a treatable disorder

(2010) W. G. Leen et al.   BRAIN

Subcutaneous insulin-like growth factor-1 treatment in spinocerebellar ataxias: An open label clinical trial

(2010) Javier Arpa et al.   MOVEMENT DISORDERS

Coenzyme Q10-responsive ataxia: 2-year-treatment follow-up

(2010) Merce Pineda et al.   MOVEMENT DISORDERS

Riluzole in cerebellar ataxia: A randomized, double-blind, placebo-controlled pilot trial

(2010) G. Ristori et al.   NEUROLOGY

Intensive coordinative training improves motor performance in degenerative cerebellar disease

(2009) W. Ilg et al.   NEUROLOGY

Caring for Machado–Joseph disease: Current understanding and how to help patients

(2009) Anelyssa D'Abreu et al.   PARKINSONISM & RELATED DISORDERS

Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient

(2009) Ninette Amariglio et al.   PLOS MEDICINE

Spinocerebellar ataxias caused by polyglutamine expansions: A review of therapeutic strategies

(2008) Benjamin R. Underwood et al.   CEREBELLUM