期刊
ACTA TROPICA
卷 196, 期 -, 页码 30-36出版社
ELSEVIER
DOI: 10.1016/j.actatropica.2019.05.004
关键词
Exosomes; Excretory-Secretory products; Proteomics; Transcriptomics; Cytokines
资金
- National Key Research and Development Program of China [2017YFD0501200]
Parasites use excretory-secretory pathways to communicate with the host. Characterization of exosomes within the excretory-secretory products reveal by which parasites manipulate their hosts. Parasite derived exosomes provide a mechanistic framework for protein and miRNAs transfer. Transcriptomics and proteomics of parasite exosomes identified a large number of miRNAs and proteins being utilized by parasites in their survival, reproduction and development. Characterization of proteins and miRNAs in parasite secreted exosomes provide important information on host-parasite communication and forms the basis for future studies. In this review, we summarize recent advances in isolation and molecular characterization (protein and miRNAs) of parasite derived exosomes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据