Article
Nanoscience & Nanotechnology
Wei Zhang, Yue Song, Yunyun Wang, Yingchao Gong, Lei Shang, Rongna Ma, Liping Jia, Qingwang Xue, Yuchang Du, Shuijian He, Huaisheng Wang
Summary: In this study, a new luminophore was developed and a dual-potential ECL ratiometric immunosensor was fabricated using perylene as a chromophore to detect alpha-fetoprotein (AFP). The biosensor showed a linear response for AFP from 10 fg mL(-1) to 100 pg mL(-1) with a detection limit of 3.33 fg mL(-1), and demonstrated good application in real sample detection.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Analytical
Yixin Nie, Peilin Wang, Qiang Ma, Xingguang Su
Summary: Based on electronic metal-support interaction (EMSI), a gold single atom confined MXene (AuSA/MXene) heterostructure was developed as a highly efficient electrochemiluminescence (ECL) functional material, which improved the electrochemical properties and expanded the sensing application of MXenes. The AuSA/MXene heterostructure exhibited high catalytic activity and electrical activity, enabling the construction of a high-efficiency ECL sensor for specific substance detection.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Haidong Li, Han Zhou, Tian Zhang, Zhicheng Zhang, Guangyue Zhao, Chengyin Wang
Summary: In this study, a new ECL biosensor with high anti-interference capacity was developed using carbonized polydopamine nanotubes (C-DPANTs). The C-PDANTs enhanced both cathodic and anodic luminol ECL and significantly reduced interference caused by reactive oxygen species (ROS). By integrating cholesterol oxidase (ChOx) with C-PDANTs, the ECL biosensor demonstrated sensitive and selective detection of cholesterol.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Chemistry, Analytical
Ping Zhang, Qirui Shen, Jiangru Wang, Miaomiao Yu, Qi Kang, Wei Zhang, Guizheng Zou
Summary: In this study, a potential-resolved electrochemiluminescence multiplex immunoassay was developed using zirconium-based metal-organic framework nanoparticles and CdTe nanocrystals as ECL tags. The intense self-ECL from Zr-ADIP-HMT nanoparticles was applied to the MIA without an exogenous anodic coreactant, enabling the detection of lung cancer biomarkers with low detection limits. This method eliminates interference from multiplex coreactants and enhances the ECL intensity.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Wei Zhang, Xiaomin Cui, Fenghua Li, Wei Yan, Yunyun Wang, Lei Shang, Rongna Ma, Liping Jia, Chuan Li, Huaisheng Wang
Summary: This study reports a ECL ratiometric system constructed using PDI-CH3 and g-C3N4 for detecting tumor marker CEA. The system achieves ultra-sensitive linear response through dual-quenching mechanism, and demonstrates good detection limit and recovery performance.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Spectroscopy
Ying Bao, Kexin Han, Zhifang Ding, Yue Li, Ting Li, Ming Guan, Guixin Li
Summary: Polypyrrole-luminol-AuNPs nanocomposites were prepared and utilized for a label-free electrochemiluminescence (ECL) immunosensor for detecting carbohydrate antigen 153 (CA153). The nanocomposites exhibited excellent ECL activity and good film-forming property, allowing them to be fixed on electrode surface without the need for additional film-forming materials.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Yu Du, Siqi Yu, Huangxian Ju
Summary: A quenching-typed electrochemiluminescence immunosensing method was proposed for protein detection using tungsten-based polyoxometalate nanoclusters and free radicals. The method demonstrated excellent detection limit and detectable range.
ANALYTICA CHIMICA ACTA
(2022)
Article
Electrochemistry
Xiaoli Qin, Liuqing Yang, Ziying Zhan, Edward Cieplechowicz, Kenneth Chu, Congyang Zhang, Sara Jahanghiri, Gregory C. Welch, Zhifeng Ding
Summary: The ECL performance and absolute efficiency of a graphene-like N-annulated PDI derivative, tPDI2N-trimethylbenzyl (tPDI2N-TMB), in annihilation and coreactant pathways with TPrA and BPO were investigated. The relative ECL efficiency of the tPDI2N-TMB/TPrA system was found to be 165%, demonstrating its high potential as an optoelectronically active material.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Hongxia Ning, Fengyu Liu, Tongkai Zhang, Yilong Zhao, Yingzheng Li, Ziqi Zhao, Chang Liu, Wei Zhang, Huaisheng Wang, Fusheng Li
Summary: An ECL sensor was fabricated based on the layer-by-layer assembly of PMPDI and Zr-IV ions on a mesoporous ITO substrate. The LBL assembly decreased the aggregation of PDIs and increased their loading on the substrate, resulting in sensitive and selective detection of dopamine.
ANALYTICA CHIMICA ACTA
(2022)
Article
Nanoscience & Nanotechnology
Edward Cieplechowicz, Rahim Munir, Michael A. Anderson, Erin L. Ratcliff, Gregory C. Welch
Summary: In this study, perylene diimide films were successfully formed from green solvents for use as electron transporting layers in inverted-type organic photovoltaics. Functionalized PDIN-H films showed improved device power conversion efficiency when used to modify the surface of ZnO in air-processed and tested inverted-type organic photovoltaics.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Analytical
Yunyun Wang, Yanmo Li, Wei Zhang, Peng Yin, Lei Shang, Rongna Ma, Liping Jia, Qingwang Xue, Shuijian He, Huaisheng Wang
Summary: A novel perylene diimide molecule was designed to self-assemble into a nanostructure, reducing aggregation and enhancing luminescence. The immunosensor fabricated using this luminescent material showed a wider linear response range and lower detection limit, demonstrating good feasibility in human serum samples.
Review
Medicine, Research & Experimental
Shijun Wang, Shu Zhu, Ziqi Kang, Yidan Chen, Xiancheng Liu, Zixin Deng, Kun Hu, Guixue Wang, Yuchan Zhang, Guangchao Zang
Summary: The potential-resolved strategy has great value in ECL biosensing, especially in ratiometric ECL sensors, multiplex ECL sensors, and multicolor ECL sensors. It can provide more accurate analysis results and broader application prospects.
Article
Chemistry, Analytical
Guizheng Zou, Xuwen Gao, Xiancheng Liu, Ying Zeng, Qingqing Zhang, Bin Zhang
Summary: This study developed a highly monochromatic and bandgap-engineered ECL luminophore and achieved spectrum-resolved multiplexing detection of different targets. The method does not require signal amplification and avoids interference between immunoassays and DNA probe detection.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Morteza Hosseini, Ebtesam Sobhanie, Foad Salehnia, Guobao Xu, Hodjattallah Rabbani, Mahsa Naghavi Sheikholeslami, Ali Firoozbakhtian, Niloufar Sadeghi, Mohammad Hossein Farajollah, Mohammad Reza Ganjali, Houman Vosough
Summary: Coronavirus disease (COVID-19) poses a global threat to public health, and rapid and accurate diagnosis of SARS-CoV-2 is crucial. We developed a sensitive and high-throughput electrochemiluminescence immunosensor based on antigen detection for early clinical diagnosis of COVID-19.
BIOELECTROCHEMISTRY
(2022)
Article
Engineering, Environmental
Li Song, Guangrong Kuang, Gui Zhang, Jiang Guo, Yingzi Fu
Summary: A new nanoflower-like iridium(III) J-aggregate (T-Ir) was prepared and used as a luminophore with good electrochemiluminescence (ECL) activity. Through a sandwich immunoreaction, detection of carcinoembryonic antigen (CEA) was achieved by utilizing T-Ir as the energy donor and gold nanoparticles capped cuprous oxide nanocubes (Cu2O@Au) as the energy acceptor. The proposed immunosensor exhibited excellent sensitivity, selectivity, reproducibility, and practicability, indicating its potential in disease diagnosis.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Substance Abuse
Neal Shah, Matthew Nali, Cortni Bardier, Jiawei Li, James Maroulis, Raphael Cuomo, Tim K. Mackey
Summary: This study used unsupervised machine learning to analyze the sales of electronic nicotine delivery systems (ENDS) on Instagram. The results showed that there is a significant amount of unregulated ENDS sales on Instagram, including flavored products, and many websites lack age verification. These findings may violate Instagram's policies and US laws, highlighting the need for stronger regulation to prevent youth access to and use of ENDS.
Article
Computer Science, Artificial Intelligence
Lingbo Liu, Zewei Yang, Guanbin Li, Kuo Wang, Tianshui Chen, Liang Lin
Summary: This paper discusses an important task in land remote-sensing analysis, which is the automatic extraction of traffic roads from remote-sensing data. To address this problem, the authors introduce a novel neural network framework that utilizes the complementary information from different data sources to enhance the accuracy and robustness of road extraction.
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS
(2023)
Article
Construction & Building Technology
Bing Cui, Huanling Wu, Canhui Zhao, Jiaping Liu, Zhiming Guo
Summary: Nanjing Jiangxinzhou Yangtze River Bridge is an innovative cable-stayed bridge in China with a unique steel-concrete composite structure. With the use of new materials, such as coarse aggregate reactive powder concrete, it has significantly improved the manufacturing speed and performance of the bridge, making significant contributions to the development of cable-stayed bridges.
STRUCTURAL ENGINEERING INTERNATIONAL
(2023)
Article
Cell Biology
Nan Shan Zhong, Wei Lai Tong, Yu Zhang, Shi Ning Xiao, Jia Ming Liu, An An Li, Ge Liang Yao, Qing Lin, Zhi Li Liu
Summary: HELQ plays a tumor-suppressive role in non-small-cell lung cancer and has the potential to be a predictive biomarker for prognosis and treatment of lung cancer.
CELL BIOLOGY INTERNATIONAL
(2023)
Article
Materials Science, Paper & Wood
Jianjun Gu, Xiaofei Yan, Dongming Qi, Ruyi Xie, Xiaoming Yang, Yaobang Li, Jiawei Li
Summary: In this study, a durable multifunctional coating was successfully fabricated on cotton fabric, providing it with flame retardant, antibacterial, superhydrophobic and self-cleaning properties. The coated fabric exhibited excellent durability even after multiple washing cycles.
Article
Green & Sustainable Science & Technology
Gang Liu, Zhitao Han, Jiawei Li, Zhen Wang, Shaosi Cheng, Yubin Liu, Jing Yu, Xinxiang Pan
Summary: A novel method for removing pre-oxidized NOx using Na2SO3/THS composite solution is proposed in this study, aiming to achieve high NOx absorption efficiency and low nitrate concentration in scrubbed wastewater simultaneously.
ENVIRONMENTAL PROGRESS & SUSTAINABLE ENERGY
(2023)
Review
Materials Science, Textiles
Shifeng Wu, Jiawei Li, Chongwen Yu
Summary: This paper proposes a simulation method for the fiber arrangement in slub yarn and uses the finite element method to simulate the twist distribution of slub yarn, which is consistent with actual spinning results. The research is significant for further exploration of the properties of slub yarn.
TEXTILE RESEARCH JOURNAL
(2023)
Article
Medical Informatics
Jiajun Liu, Shein-Chung Chow
Summary: In clinical trials, when the primary analysis fails to meet the study objective, the observed positive results in a specific sub-population analysis raise the question of whether they can be used to support regulatory submission. This article proposes several statistical evaluations for confirming the integrity and validity of the observed sub-population analysis results. The evaluations address selection bias, reproducibility, consistency, generalizability, and sensitivity index. A numerical example of a global clinical trial is presented, along with recommendations for incorporating statistical evaluations. Real-world data and evidence are suggested as possible solutions to address regulatory concerns and increase statistical power.
THERAPEUTIC INNOVATION & REGULATORY SCIENCE
(2023)
Article
Computer Science, Interdisciplinary Applications
Jiawei Li, Pavel Tomin, Hamdi Tchelepi
Summary: There is an increasing interest in developing robust and efficient sequential methods for reservoir simulation. The sequential fully implicit Newton (SFIN) method addresses the slow sequential coupling convergence issue when flow and transport problems are strongly coupled. However, the original SFIN algorithm requires fixed primary variables during the simulation. In this work, strategies are proposed to handle inconsistent primary variables and extend the SFIN method to the natural black-oil formulation.
COMPUTATIONAL GEOSCIENCES
(2023)
Article
Computer Science, Interdisciplinary Applications
Maolin Yang, Pingyu Jiang, Jiajun Liu
Summary: Social product design (SPD) is a new pattern that utilizes socialized design resources to enhance design power with lower costs. However, the characteristics of socialized designers (SDs) result in problems such as low collaboration efficiency and trust. To address these problems, a Blockchain and modified Best-worst algorithm enhanced Blackboard model is established. The model improves collaboration efficiency and provides reliable recording and estimation of SDs' contributions during the SPD process, enhancing the operability of SPD application.
COMPUTERS & INDUSTRIAL ENGINEERING
(2023)
Article
Dentistry, Oral Surgery & Medicine
Taotao Zhang, Kuan Yang, Yujiang Chen, Yuran Jiang, Zhifei Zhou, Jiajia Liu, Yang Du, Lulu Wang, Xinxin Han, Xingan Wu, Xiaojing Wang
Summary: This study found that nicotine treatment impairs autophagy function in periodontal ligament stem cells, leading to the production of inflammatory factors. Activation of α7nAChR by nicotine upregulates NEAT1, which in turn decreases autophagy flux by downregulating STX17.
JOURNAL OF PERIODONTAL RESEARCH
(2023)
Article
Polymer Science
Yanning Zeng, Jiawei Li, Chaoying Hu, Bin Yang, Zhao Ning
Summary: Novel self-healing, weldable, and recyclable HTPB-based PU networks with dual reversible covalent bonds were fabricated using one-pot polycondensation. The networks exhibited good mechanical properties and the ability to be recycled.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2023)
Article
Spectroscopy
Haipei Zou, Huanling Liu, Qingfang Mu, Kai Zhang, Yuzhi Song, Lili Lin, Yuanyuan Xu, Chuan-Kui Wang, Jianzhong Fan
Summary: This study investigates the relationship between molecular structures and luminescent properties, and proposes theoretically efficient TSCT-based TADF molecules. These molecules have a large number of substitutions and adopt twist structures to achieve small energy gaps between the lowest excited states.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Spectroscopy
Kang Wang, Gang Li, Mei Zhou, Huiquan Wang, Dan Wang, Ling Lin
Summary: This paper presents a novel method called spectral elimination for noninvasive quantitative analysis of human blood components. The method reduces the influence of non-target components on the detection of target components, resulting in high accuracy. Experimental results demonstrate the effectiveness of the method in predicting the content of multiple human blood components.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Computer Science, Artificial Intelligence
Xiang Shi, Yinpeng Liu, Jiawei Liu, Qikai Cheng, Wei Lu
Summary: Scientific papers are crucial for academic communication, but many of them lack in-depth research and present core content ambiguously, hindering the progression of science and technology. To address this challenge, the INTEGrity vERification (INTEGER) task is introduced to help researchers assess the integrity of their papers and verify the clarity of each knowledge unit. A multi-task learning model utilizing Tucker decomposition and span-level attention mechanism is proposed to accurately identify terms and their integrity. Experimental results show the effectiveness of the model.
EXPERT SYSTEMS WITH APPLICATIONS
(2024)
