Impaired nuclear functions in micronuclei results in genome instability and chromothripsis

Telomere dysfunction and chromothripsis

(2016) Aurélie Ernst et al.   INTERNATIONAL JOURNAL OF CANCER

Chromothripsis and Kataegis Induced by Telomere Crisis

(2015) John Maciejowski et al.   CELL

A cell-based model system links chromothripsis with hyperploidy

(2015) B. R. Mardin et al.   Molecular Systems Biology

Chromothripsis from DNA damage in micronuclei

(2015) Cheng-Zhong Zhang et al.   NATURE

Whole–genome characterization of chemoresistant ovarian cancer

(2015) Ann-Marie Patch et al.   NATURE

Whole genomes redefine the mutational landscape of pancreatic cancer

(2015) Nicola Waddell et al.   NATURE

Chromothripsis-like patterns are recurring but heterogeneously distributed features in a survey of 22,347 cancer genome screens

(2014) Haoyang Cai et al.   BMC GENOMICS

Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

(2014) Yilong Li et al.   NATURE

Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis

(2014) Katia Nones et al.   Nature Communications

53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions

(2013) Elsa Callen et al.   CELL

Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei

(2013) Emily M. Hatch et al.   CELL

Chromothripsis in congenital disorders and cancer: similarities and differences

(2013) Wigard P Kloosterman et al.   CURRENT OPINION IN CELL BIOLOGY

Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms

(2013) A. Malhotra et al.   GENOME RESEARCH

RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection

(2013) J. Ross Chapman et al.   MOLECULAR CELL

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

(2012) Tobias Rausch et al.   CELL

DNA breaks and chromosome pulverization from errors in mitosis

(2012) Karen Crasta et al.   NATURE

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

(2012) Jan J. Molenaar et al.   NATURE

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

Give me a break, but not in mitosis

(2011) Simona Giunta et al.   CELL CYCLE

The xeroderma pigmentosum pathway: Decision tree analysis of DNA quality

(2011) Hanspeter Naegeli et al.   DNA REPAIR

Nuclear envelope defects impede a proper response to micronuclear DNA lesions

(2011) Mariona Terradas et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Generation of Micronuclei during Interphase by Coupling between Cytoplasmic Membrane Blebbing and Nuclear Budding

(2011) Koh-ichi Utani et al.   PLoS One

The lamin protein family

(2011) Travis A Dittmer et al.   GENOME BIOLOGY

Assembly and function of DNA double-strand break repair foci in mammalian cells

(2010) Simon Bekker-Jensen et al.   DNA REPAIR

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism

(2010) Sarah L. Thompson et al.   JOURNAL OF CELL BIOLOGY

Flow cytometric analysis of micronuclei in mammalian cell cultures: past, present and future

(2010) S. Avlasevich et al.   MUTAGENESIS

Micronucleus formation detected by live-cell imaging

(2010) Y. Huang et al.   MUTAGENESIS

Molecular mechanisms of the origin of micronuclei from extrachromosomal elements

(2010) N. Shimizu   MUTAGENESIS

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

(2010) M. Fenech et al.   MUTAGENESIS

Micronuclei frequency in peripheral blood lymphocytes and cancer risk: evidence from human studies

(2010) S. Bonassi et al.   MUTAGENESIS

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

(2010) Peter Bouwman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

(2010) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining

(2009) Brandi L. Mahaney et al.   BIOCHEMICAL JOURNAL

DNA lesions sequestered in micronuclei induce a local defective-damage response

(2009) Mariona Terradas et al.   DNA REPAIR

Telomere dysfunction and chromosome structure modulate the contribution of individual chromosomes in abnormal nuclear morphologies

(2009) J. Pampalona et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC

(2008) D. Hoogstraten et al.   JOURNAL OF CELL SCIENCE

Micronuclei frequency in peripheral blood lymphocytes of cancer patients: A meta-analysis

(2008) G IARMARCOVAI et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH