BET Bromodomain Inhibitors Suppress Inflammatory Activation of Gingival Fibroblasts and Epithelial Cells From Periodontitis Patients
出版年份 2019 全文链接
标题
BET Bromodomain Inhibitors Suppress Inflammatory Activation of Gingival Fibroblasts and Epithelial Cells From Periodontitis Patients
作者
关键词
-
出版物
Frontiers in Immunology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-04-30
DOI
10.3389/fimmu.2019.00933
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Periodontitis in US Adults
- (2018) Paul I. Eke et al. JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
- TIMP-1 association with collagen type I overproduction in hereditary gingival fibromatosis
- (2018) Katarzyna Gawron et al. ORAL DISEASES
- Killed Whole-Cell Oral Cholera Vaccine Induces CCL20 Secretion by Human Intestinal Epithelial Cells in the Presence of the Short-Chain Fatty Acid, Butyrate
- (2018) Ju-Ri Sim et al. Frontiers in Immunology
- Matrix Metalloproteinases as Regulators of Periodontal Inflammation
- (2017) Cavalla Franco et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Host modulation therapy with anti-inflammatory agents
- (2017) Philip M. Preshaw PERIODONTOLOGY 2000
- Brd4 modulates the innate immune response through Mnk2–eIF4E pathway-dependent translational control of IκBα
- (2017) Yan Bao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The suppression of bromodomain and extra-terminal domain inhibits vascular inflammation by blocking NF-κB and MAPK activation
- (2016) Mingcheng Huang et al. BRITISH JOURNAL OF PHARMACOLOGY
- BET Inhibition AttenuatesHelicobacter pylori–Induced Inflammatory Response by Suppressing Inflammatory Gene Transcription and Enhancer Activation
- (2016) Jinjing Chen et al. JOURNAL OF IMMUNOLOGY
- Epigenetic drug discovery: breaking through the immune barrier
- (2016) David F. Tough et al. NATURE REVIEWS DRUG DISCOVERY
- BET bromodomain inhibition suppresses graft-versus-host disease after allogeneic bone marrow transplantation in mice
- (2015) Y. Sun et al. BLOOD
- Epigenetic Modifications of Histones in Periodontal Disease
- (2015) M.D. Martins et al. JOURNAL OF DENTAL RESEARCH
- Class I and II histone deacetylase expression in human chronic periodontitis gingival tissue
- (2015) M. D. Cantley et al. JOURNAL OF PERIODONTAL RESEARCH
- Chemokine Function in Periodontal Disease and Oral Cavity Cancer
- (2015) Sinem Esra Sahingur et al. Frontiers in Immunology
- The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts
- (2014) Kerstin Klein et al. ANNALS OF THE RHEUMATIC DISEASES
- BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak-STAT signaling in a gene-specific manner in human monocytes
- (2014) Chun Hin Chan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction
- (2014) S. Meng et al. JOURNAL OF DENTAL RESEARCH
- Letter to the Editor, “BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction”
- (2014) S.J. Hogg et al. JOURNAL OF DENTAL RESEARCH
- Peptidylarginine deiminase fromPorphyromonas gingivaliscontributes to infection of gingival fibroblasts and induction of prostaglandin E2-signaling pathway
- (2014) K. Gawron et al. Molecular Oral Microbiology
- Brd4 Is Essential for IL-1β-Induced Inflammation in Human Airway Epithelial Cells
- (2014) Younis M. Khan et al. PLoS One
- The Drug Vehicle and Solvent N-Methylpyrrolidone Is an Immunomodulator and Antimyeloma Compound
- (2014) Jake Shortt et al. Cell Reports
- Gingival fibroblasts from periodontitis patients exhibit inflammatory characteristics in vitro
- (2013) Keum Jin Baek et al. ARCHIVES OF ORAL BIOLOGY
- Breaking bad: Manipulation of the host response byPorphyromonas gingivalis
- (2013) George Hajishengallis et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Inflammatory mediators in the pathogenesis of periodontitis
- (2013) Tülay Yucel-Lindberg et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- BET bromodomain inhibition suppresses TH17-mediated pathology
- (2013) Deanna A. Mele et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Establishment and characterization of a telomerase immortalized human gingival epithelial cell line
- (2013) C. E. Moffatt-Jauregui et al. JOURNAL OF PERIODONTAL RESEARCH
- From ApoA1 upregulation to BET family bromodomain inhibition: Discovery of I-BET151
- (2012) Olivier Mirguet et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The bromodomain interaction module
- (2012) Panagis Filippakopoulos et al. FEBS LETTERS
- Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors
- (2012) H. S. Bandukwala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Place your BETs: the therapeutic potential of bromodomains
- (2012) R.K. Prinjha et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay
- (2011) Aleksander M Grabiec et al. ANNALS OF THE RHEUMATIC DISEASES
- Inhibition of Osteoclast Differentiation and Bone Resorption byN-Methylpyrrolidone
- (2011) Chafik Ghayor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Periodontal ligament and gingival fibroblasts from periodontitis patients are more active in interaction with Porphyromonas gingivalis
- (2011) N. Scheres et al. JOURNAL OF PERIODONTAL RESEARCH
- Histone deacetylase inhibitors and periodontal bone loss
- (2011) M. D. Cantley et al. JOURNAL OF PERIODONTAL RESEARCH
- Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery
- (2011) Martin Philpott et al. Molecular BioSystems
- Epigenetic regulation of human β-defensin 2 and CC chemokine ligand 20 expression in gingival epithelial cells in response to oral bacteria
- (2011) L Yin et al. Mucosal Immunology
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
- (2011) Mark A. Dawson et al. NATURE
- Suppression of inflammation by a synthetic histone mimic
- (2010) Edwige Nicodeme et al. NATURE
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation
- (2009) Diana C. Hargreaves et al. CELL
- Cytokines That Promote Periodontal Tissue Destruction
- (2008) Dana Graves JOURNAL OF PERIODONTOLOGY
- Brd4 Coactivates Transcriptional Activation of NF- B via Specific Binding to Acetylated RelA
- (2008) B. Huang et al. MOLECULAR AND CELLULAR BIOLOGY
- The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription
- (2008) Gary LeRoy et al. MOLECULAR CELL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More