Article
Biochemistry & Molecular Biology
Aida Sadeghian, Mahshid Kharaziha, Maryam Khoroushi
Summary: The study developed a novel hydrogel for dental pulp regeneration, which consists of dentin extracellular matrix (dECM) loaded with gelatin methacrylate (GelMA) and bioactive glass (BG). The researchers investigated the influence of dECM content on the hydrogel's characteristics and biological responses. The results showed that increasing dECM content improved the compressive strength, bioactivity, and biocompatibility of the hydrogel, making it suitable for future clinical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Ceramics
Mari Lallukka, Amel Houaoui, Marta Miola, Susanna Miettinen, Jonathan Massera, Enrica Verne
Summary: Fighting the formation of bacterial biofilm and providing a bioactive environment for bone regeneration is a significant challenge in surgery. Bioactive glasses doped with silver (Ag) or copper (Cu) ions offer a potential non-antibiotic solution. This study evaluates the cytocompatibility of Ag and Cu-doped bioactive glasses and finds that fibronectin adsorption improves the cytocompatibility of Ag-doped glass.
CERAMICS INTERNATIONAL
(2023)
Article
Physiology
Yam Prasad Aryal, Chang-Yeol Yeon, Tae-Young Kim, Eui-Seon Lee, Shijin Sung, Elina Pokharel, Ji-Youn Kim, So-Young Choi, Hitoshi Yamamoto, Wern-Joo Sohn, Youngkyun Lee, Seo-Young An, Chang-Hyeon An, Jae-Kwang Jung, Jung-Hong Ha, Jae-Young Kim
Summary: The study demonstrates that apigenin can promote dentin regeneration by modulating inflammation and activating signaling regulations.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Chemistry, Physical
Ermin Nie, Jiali Yu, Rui Jiang, Xiangzhen Liu, Xiang Li, Rafiqul Islam, Mohammad Khursheed Alam
Summary: This systematic review evaluated the dentin regeneration efficacy of direct pulp capping biomaterials, concluding that MTA and Biodentine can induce dentin regeneration. The results suggest that MTA and its variants have better efficacy in the DPC procedure for dentin regeneration.
Article
Polymer Science
Shaher Bano, Memoona Akhtar, Muhammad Yasir, Muhammad Salman Maqbool, Akbar Niaz, Abdul Wadood, Muhammad Atiq Ur Rehman
Summary: Silver and strontium doped mesoporous bioactive glass nanoparticles were synthesized and found to possess strong antibacterial properties and potential for promoting osteogenesis, making them suitable for applications in bone tissue engineering.
Article
Materials Science, Ceramics
Rong Guo, Xinghui Hou, Dakui Zhao, Huili Wang, Caixin Shi, Ying Zhou
Summary: In this study, a freeze-drying method was used to synthesize a biologically active magnesium and strontium co-doped bioactive glass/chitosan composite scaffold. The as-prepared scaffold exhibited a three-dimensional honeycombed porous structure, and the porosity, pore size, swelling, and degradation rate could be controlled by adjusting the content of MSBG powders. The compressive modulus of the composite scaffold reached its maximum value when the mass ratio of MSBG to CS was 2:4. In vitro experiments demonstrated that MSBG greatly improved the generation capacity of hydroxyapatite in the composite scaffold, making it a promising candidate for bone tissue engineering.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2022)
Article
Engineering, Biomedical
Natalia Pajares-Chamorro, Josh M. M. Lensmire, Neal D. D. Hammer, Jonathan W. W. Hardy, Xanthippi Chatzistavrou
Summary: This study explored the antibacterial capabilities of silver-doped bioactive glass microparticles and revealed the unedited mechanisms of inhibition against MRSA. The antibacterial properties were not limited to the delivery of silver ions but rather a combination of antibacterial degradation by-products. Additionally, the restorative functionality of the glass allowed the effective use of antibiotics that MRSA resists.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Article
Cell Biology
Keita Ipposhi, Atsushi Tomokiyo, Taiga Ono, Kozue Yamashita, Muhammad Anas Alhasan, Daigaku Hasegawa, Sayuri Hamano, Shinichiro Yoshida, Hideki Sugii, Tomohiro Itoyama, Marina Ogawa, Hidefumi Maeda
Summary: SFRP1 plays a crucial role in dentinogenesis and promoting reparative dentin formation, as demonstrated by its effects on odontoblastic differentiation and mineralized nodule formation. The strong expression of SFRP1 in mature odontoblasts indicates its importance in dental pulp preservation and response to injury. Additionally, SFRP1 regulates odontoblast-related gene expression, particularly BMP-2, affecting the formation and structure of reparative dentin.
Article
Materials Science, Ceramics
Sara Mortazavi, Mansour Rahsepar, Saeid Hosseinzadeh
Summary: Silver-containing mesoporous bioglass powders were successfully synthesized using sol-gel and evaporation-induced self-assembly methods. The powders exhibited a smooth surface morphology, cubic mesoporous structure, and showed antibacterial activity against Escherichia coli, Salmonella, and Listeria monocytogenes.
CERAMICS INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Matej Par, Andrea Gubler, Thomas Attin, Zrinka Tarle, Andro Tarle, Tobias T. Tauboeck
Summary: This in vitro study investigated the protective effects of different types of experimental and commercial restorative dental materials on dentin against acid-induced demineralization. The results showed that a higher percentage of low-Na F-containing bioactive glass was needed to protect dentin compared to bioactive glass 45S5. The protective effect of these materials on dentin was found to be of shorter duration compared to enamel.
Review
Dentistry, Oral Surgery & Medicine
S. Behzadi, Y. Mohammadi, L. Rezaei-Soufi, A. Farmany
Summary: This study evaluated the occlusion effects of bioactive glass and hydroxyapatite on dental tubules. The results showed that both bioactive glass and hydroxyapatite had the potential efficacy in dentin tubule occlusion compared to the control.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Materials Science, Ceramics
Alieza Saatchi, Ahmad Razaghian Arani, Amirhossein Moghanian, Masoud Mozafari
Summary: The study demonstrated that increasing the content of cerium-doped bioactive glass improved the cytocompatibility and cell attachment of the scaffolds, although excessively high ratios decreased wettability. Increasing the weight ratio of cerium-doped bioactive glass up to 40% was effective for soft tissue engineering applications.
CERAMICS INTERNATIONAL
(2021)
Review
Biochemistry & Molecular Biology
Dorotea Petrovic, Dora Galic, Davor Seifert, Nikolina Lesic, Martina Smolic
Summary: The aim of this systematic review is to compare the effectiveness of home and office desensitizers containing bioactive glass with control groups in randomized controlled trials conducted between 2018 and 2022. Nine articles were evaluated and seven were included in the review. The results showed that fluoro calcium phosphosilicate (FCPS) may be the most effective long-term treatment option for dentin hypersensitivity (DH) symptom reduction in adult participants.
Article
Dentistry, Oral Surgery & Medicine
Samantha Ariadne Alves de Freitas, Paulo Vitor Campos Ferreira, Edilausson Moreno Carvalho, Mayra Alejandra Nunez Aldaz, Alessandro Dourado Loguercio, Renata Grazziotin-Soares, Ceci Nunes Carvalho, Adriana de Fatima Vasconcelos Pereira, Jose Bauer
Summary: Experimental bioactive pastes containing NbG and 45S5 glasses, regardless of concentration, were effective in reducing dentin permeability compared to pastes without bioactive glasses. SEM/EDS and micro-Raman analyses revealed that both types of bioactive pastes produced mineral precipitates that obliterated dentinal tubules by day 21.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Itallo Emidio Lira Viana, Roger Borges, Juliana Marchi, Sabrina Feitosa, Marcia Martins Marques, Tais Scaramucci
Summary: The study evaluated the effect of experimental bioactive glass on dentin permeability and erosive tooth wear, finding that the material reduced dentin permeability after application but showed diminished effect after cycling, and it was not able to fully protect dentin against erosive tooth wear.
JOURNAL OF DENTISTRY
(2022)
Article
Materials Science, Ceramics
Natalia Pajares-Chamorro, Yadav Wagley, Neal Hammer, Kurt Hankenson, Xanthippi Chatzistavrou
Summary: The study aims to develop a site-specific drug delivery multifunctional vehicle with the ability to clear resistant bacteria and promote tissue healing. The Ag-BG@vanc conjugate showed strong antibacterial properties against vancomycin-resistant MRSA strains, providing new hope in combating antibiotic resistance.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2022)
Article
Cell & Tissue Engineering
Nureddin Ashammakhi, Amin GhavamiNejad, Rumeysa Tutar, Annabelle Fricker, Ipsita Roy, Xanthippi Chatzistavrou, Ehsanul Hoque Apu, Kim-Lien Nguyen, Taby Ahsan, Ippokratis Pountos, Edward J. Caterson
Summary: The field of tissue engineering is advancing rapidly, with a focus on addressing the needs of disease states and creating functional products in regenerative medicine. The key to success lies in important ideas and collaborative research efforts between academia and industry.
TISSUE ENGINEERING PART B-REVIEWS
(2022)
Article
Physics, Multidisciplinary
Ye Chen, Lijuan Ge, Xinglin Wang, Ming Shen
Summary: The propagation dynamics of two-dimensional Airy Gaussian beams and Airy Gaussian vortex beams in local and nonlocal nonlinear media were investigated numerically. The self-healing and collapse of the beams depend on the distribution factor b and the topological charge m. By utilizing nonlocality, stable Airy Gaussian beams and Airy Gaussian vortex beams with larger amplitudes can be obtained, which always collapse in local nonlinear media. When the distribution factor b is large enough, the Airy Gaussian vortex beam will transform into quasi-vortex solitons in nonlocal nonlinear media.
COMMUNICATIONS IN THEORETICAL PHYSICS
(2022)
Article
Food Science & Technology
Yuan-ting Zhu, Shao-lan Zhang, Qian Ma, Yong Zuo, Rui-tong Li, Jian-xia Yang, Rui-yu Zhu, Li-hong Ge
Summary: The research investigated the metabolic characteristics of inulin in the probiotic L. plantarum QS7T derived from Sichuan pickle, showing its efficient utilization of inulin as a carbon source. Genomic and transcriptomic analysis revealed the molecular mechanisms involved in inulin consumption by the strain QS7T, including the upregulation of genes associated with carbohydrate metabolism and transport.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Jingzhi Li, Lihong Ge, Yuming Zhao, Yue Zhai, Nanquan Rao, Xiaojing Yuan, Jie Yang, Jing Li, Shi Yu
Summary: The study found that Transforming Growth Factor-beta 2 (TGF-beta 2) promotes odontogenic differentiation and attenuates osteogenic differentiation, while Transforming Growth Factor-beta 1 (TGF-beta 1) plays an important role in regulating osteogenic differentiation and has complex effects on odontogenic differentiation.
ARCHIVES OF ORAL BIOLOGY
(2022)
Article
Urology & Nephrology
Yuxuan Li, Zhuo Liu, Xiaoyu Zhao, Peng Hong, Xun Zhao, Guodong Zhu, Shiying Tang, Liyuan Ge, Shudong Zhang, Cheng Liu, Shumin Wang, Hongxian Zhang, Lulin Ma
Summary: This study investigated perioperative clinicopathological predictors and established a predictive nomogram for survival in patients with renal cell carcinoma and venous tumor thrombus undergoing nephrectomy and thrombectomy. The results showed that hemoglobin level, sarcomatoid feature, perirenal fat invasion, histological subtype, and metastasis at surgery were independently associated with overall survival. They developed a predictive nomogram that had a good predictive performance.
INTERNATIONAL JOURNAL OF UROLOGY
(2022)
Article
Plant Sciences
Hongming Guo, Yuchao Cui, Linjuan Huang, Li Ge, Xiaorong Xu, Danyang Xue, Ming Tang, Jingsheng Zheng, Yin Yi, Liang Chen
Summary: This study identified and characterized two La proteins (OsLa1 and OsLa2) in rice, which play important roles in rice growth and development. OsLa1 modulates grain size by influencing cell expansion, while mutant OsLa2 results in thin grains and low seed-setting rate. In addition, OsLa1 and OsLa2 interact with OseIF6.1 and OsLa1 can modulate the expression of OseIF6.1.
Article
Computer Science, Information Systems
Lina Ge, Jie Wang, Guifen Zhang
Summary: This paper studies the consensus algorithm in blockchain, introducing the variants of PoS and PoS consensus algorithm, summarizing their core ideas, effects, advantages and disadvantages. The performance of the improved algorithms is compared, and the main improvement methods and common network security attacks are summarized.
SECURITY AND COMMUNICATION NETWORKS
(2022)
Article
Engineering, Biomedical
Natalia Pajares-Chamorro, Josh M. M. Lensmire, Neal D. D. Hammer, Jonathan W. W. Hardy, Xanthippi Chatzistavrou
Summary: This study explored the antibacterial capabilities of silver-doped bioactive glass microparticles and revealed the unedited mechanisms of inhibition against MRSA. The antibacterial properties were not limited to the delivery of silver ions but rather a combination of antibacterial degradation by-products. Additionally, the restorative functionality of the glass allowed the effective use of antibiotics that MRSA resists.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Article
Engineering, Environmental
Yuhui Liu, Yaning Lu, Shuang Zhang, Xiaoyan Li, Zhibin Zhang, Liya Ge, MengYu Chang, Yunhai Liu, Grzegorz Lisak, Sheng Deng
Summary: In this study, an amphiphilic ligand NND was successfully synthesized and used to enhance the adsorption capacity of MoS2 particles for UO22+ by replacing H2O through hydrogen bonding. The NND-modified MoS2 showed higher adsorption capacity and stronger stability under extreme conditions.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Biotechnology & Applied Microbiology
Yue Shi, Qi Zhang, Hai Bi, Min Lu, Yezhen Tan, Daojia Zou, Liyuan Ge, Zhigang Chen, Cheng Liu, Weimin Ci, Lulin Ma
Summary: This study provides a comprehensive understanding of the mechanisms involved in tumor thrombus formation in clear cell renal cell carcinoma (ccRCC). The results show that tumor thrombus is marked by the presence of CD8(+) T cells with an exhausted phenotype and enhanced remodeling of the extracellular matrix. In contrast, proinflammatory states and increased expression of immunosuppressive markers are found in macrophages and malignant cells from primary tumors. The interactions between tumor and stroma reshape the extracellular matrix in tumor thrombus, which is associated with poor survival.
Article
Chemistry, Physical
Wei Lai, Lihong Ge, Hua Yang, Yilin Deng, Huaming Li, Bo Ouyang, Li Xu, Jian Bao
Summary: The study successfully synthesized an excellent Cu- and Fe-co-doped Ni/Ni(OH)(2) heterostructured electrocatalyst through an electrochemical method, which exhibits outstanding dual catalytic functions for hydrogen evolution and oxygen evolution reactions.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Clinical Neurology
Yuan Yang, Dong-Ying Zhang, Yi-Lin Li, Meng Zhang, Pei-Hong Wang, Xiao-Hua Liu, Li-Na Ge, Wen-Xuan Lin, Yang Xu, Ya-Lan Zhang, Feng-Juan Li, Xu-Juan Xu, Hong-He Wu, Teris Cheung, Chee H. Ng, Hai-Xin Bo, Yu-Tao Xiang
Summary: This study assessed the prevalence, correlates, and network structure of Internet addiction among Chinese pregnant and postpartum women. The results showed that Internet addiction is common and significantly associated with lower quality of life in this population. The study also identified the central symptoms of Internet addiction and their links with quality of life.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Engineering, Environmental
Sif Guojonsdottir, Liya Ge, Ke Zhao, Grzegorz Lisak, Bing Wu
Summary: The study found that using GDM systems packed with Icelandic lava stones can efficiently treat wastewater and facilitate nitrogen removal efficiency through the presence of manganese oxide. The cleaning method significantly affects flux recovery and water permeability. Irrigating vegetables with GDM permeate has minimal impact on plant growth and heavy metal contents in soils compared to using tap water.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Computer Science, Artificial Intelligence
Yongsheng Li, Yinjuan Huang, Lina Ge, Xi Li
Summary: An ant colony algorithm based on angle guide is proposed in this paper to address the issues of local optimum and slow convergence in solving mobile robot path planning. The algorithm integrates angle factor in node selection, utilizes pheromone differential updating for different paths, and introduces pheromone chaotic disturbance updating mechanism to improve global search ability and efficiency. Simulation results demonstrate the algorithm's strong global search capability and fast convergence to the global optimum, making it feasible and effective.
INTERNATIONAL JOURNAL OF SWARM INTELLIGENCE RESEARCH
(2022)
