期刊
MICROMACHINES
卷 10, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/mi10060392
关键词
microfluidics; exosomes; clinical applications; extracellular vesicles; cancer; inflammation
类别
资金
- Foreign Experts Program of P.R. China [W099109]
- CEITEC Nano Research Infrastructure [LM2015041]
- CEITEC Brno University of Technology
- Grant Agency of the Czech Republic [GA16-11140S]
Exosomes, a type of nanovesicle, are distinct cellular entities specifically capable of carrying various cargos between cells. It has been hypothesized that exosomes, as an enriched source of biomolecules, may serve as biomarkers for various diseases. This review introduces general aspects of exosomes, presents the challenges in exosome research, discusses the potential of exosomes as biomarkers, and describes the contribution of microfluidic technology to enable their isolation and analysis for diagnostic and disease monitoring. Additionally, clinical applications of exosomes for diagnostic purposes are also summarized.
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