Article
Biophysics
Ashley M. Nelson, P. Connor Johnson, Alison R. Kavanaugh, Vicki A. Jackson, Annemarie D. Jagielo, Alyssa L. Fenech, Matthew J. Reynolds, Carlisle Topping, Alisha M. Yi, Nora Horick, Jennifer S. Temel, Joseph A. Greer, Areej El-Jawahri
Summary: An inpatient palliative care intervention during HCT improved patient QOL and mood. Components of the intervention, differences in supportive care practices, and their mediation on patient outcomes were examined. While patients in the intervention group were more likely to use specific medications, these did not mediate the intervention's impact on patient-reported outcomes. Further research is needed to explore the mechanisms through which palliative care intervention affects QOL and mood.
BONE MARROW TRANSPLANTATION
(2021)
Review
Oncology
Rita Carrilho Pichel, Alexandra Araujo, Vital Da Silva Domingues, Jorge Nunes Santos, Elga Freire, Ana Sofia Mendes, Raquel Romao, Antonio Araujo
Summary: Esophageal cancer is a leading cause of death, and most patients are not candidates for curative or systemic palliative treatment. This review aims to provide recommendations for the best supportive care for esophageal cancer, focusing on the management of its most common symptoms and complications.
Article
Psychology, Multidisciplinary
Astrid Schnabel, Florian Lordick, Paula Oberth, Markus Neuschulz, Antje Lehmann-Laue, Anja Mehnert-Theuerkauf, Andreas Hinz
Summary: This study analyzed the relationship between supportive care needs (SCNs), satisfaction with quality of life (QoL) dimensions, and the perceived importance of these dimensions among 152 cancer patients receiving palliative care. The results showed that the greatest SCNs were observed for absence of pain, while the patients were least satisfied with their physical functioning and the dimension social relationships received the highest perceived importance ratings.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Urology & Nephrology
Petros Grivas, Evgeny Kopyltsov, Po-Jung Su, Francis X. Parnis, Se Hoon Park, Yoshiaki Yamamoto, Peter C. Fong, Christophe Tournigand, Miguel A. Climent Duran, Aristotelis Bamias, Claudia Caserta, Jane Chang, Paul Cislo, Alessandra di Pietro, Jing Wang, Thomas Powles
Summary: This study compared the efficacy of first-line maintenance plus best supportive care with that of best supportive care alone in patients with advanced urothelial carcinoma. The results showed that the addition of first-line maintenance treatment significantly prolonged overall survival and had a minimal impact on quality of life.
Review
Clinical Neurology
Natalie E. Stec, Tobias Walbert
Summary: The diagnosis of a brain tumor is a life-changing event for patients and their families. Though treatment advances have been made, malignant brain tumors remain incurable and have limited long-term survival. Patients experience a high symptom burden and require palliative interventions to maintain quality of life. Advance care planning is crucial in the terminal phase of illness.
NEUROLOGICAL SCIENCES
(2022)
Article
Oncology
Eran Ben-Arye, Dana Elly, Noah Samuels, Orit Gressel, Katerina Shulman, Elad Schiff, Ofer Lavie, Amir Minerbi
Summary: The study found that high adherence to integrative care was associated with greater pain relief at 6 weeks, but not at 12 weeks, in patients undergoing chemotherapy and/or palliative care.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2021)
Article
Oncology
Li Mo, Diana L. Urbauer, Eduardo Bruera, David Hui
Summary: Supportive care and best supportive care are frequently mentioned in NCCN guidelines, with significant variations in usage between solid tumor and hematologic oncologists. Solid tumor guidelines are more likely to mention best supportive care, while hematologic guidelines are more likely to mention supportive care.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Health Care Sciences & Services
Katharine E. Brock, Nicholas P. DeGroote, Anna Roche, Annika Lee, Karen Wasilewski
Summary: The Supportive Care Clinic (SCC) has been successful as an embedded pediatric palliative care (PPC) service in pediatric oncology, achieving significant growth in outpatient visits and improving end-of-life care for children with cancer.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2022)
Review
Clinical Neurology
Adela Wu, Gabriela Ruiz Colon, Michael Lim
Summary: Brain metastases have a significant impact on the quality of life of patients, necessitating early implementation of palliative care. However, the incorporation and implementation of palliative and other supportive services in a true multidisciplinary care setting requires further attention and research. This review discusses the challenges faced by patients with brain metastases and their caregivers, as well as the current research on quality of life metrics and the role of specialty palliative care, rehabilitation services, and other healthcare providers in a comprehensive multidisciplinary care model.
FRONTIERS IN NEUROLOGY
(2022)
Article
Oncology
Samir Patel, John Austin Vargo, Adam Olson, Anita Mahajan
Summary: Radiation therapy is crucial for managing pediatric tumors but can lead to adverse events affecting quality of life. More research is needed to better manage these effects and improve outcomes for children undergoing treatment.
PEDIATRIC BLOOD & CANCER
(2021)
Article
Oncology
Baek-Yeol Ryoo, Philippe Merle, Amit S. Kulkarni, Ann-Lii Cheng, Mohamed Bouattour, Ho Yeong Lim, Valeriy Breder, Julien Edeline, Yee Chao, Sadahisa Ogasawara, Thomas Yau, Marcelo Garrido, Stephen L. Chan, Bruno Daniele, Josephine M. Norquist, Erluo Chen, Abby B. Siegel, Andrew X. Zhu, Richard S. Finn, Masatoshi Kudo
Summary: Pembrolizumab preserved health-related quality of life during treatment for advanced hepatocellular carcinoma. The positive benefit/risk profile of pembrolizumab in a second-line treatment setting for patients who previously received sorafenib is supported by these findings in combination with efficacy and safety results.
Review
Oncology
A. E. Armitage, E. Fonkem
Summary: Neurodegenerative illnesses have limited treatments and progressive clinical course. Supportive care enhances patient outcomes and quality of life, making it crucial in conjunction with disease management. This article examines the role of supportive palliative care in neurologic patients, comparing glioblastoma with Parkinson's disease as representative examples.
FRONTIERS IN ONCOLOGY
(2023)
Review
Hematology
Hon Wai Benjamin Cheng, Ka On Lam
Summary: The article highlights the often poor prognoses of patients with hematologic malignancy and the underutilization of palliative care services. It proposes a modified palliative care model in hemato-oncology, advocating for early intervention, comprehensive care, and tailored care based on disease progression.
ANNALS OF HEMATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Elizabeth Palmer Kelly, J. Madison Hyer, Anghela Z. Paredes, Diamantis Tsilimigras, Bonnie Meyer, Hanci Newberry, Timothy M. Pawlik
Summary: Among patients with hepatopancreatic (HP) cancer, a significant proportion utilize supportive spiritual care, which should be integrated into their care. Younger age and religious identity were associated with higher likelihood of receiving spiritual care.
Article
Multidisciplinary Sciences
Dong-Won Kang, Yoon-Bo Shim, Eui-Kyung Lee, Mi-Hai Park
Summary: This study assessed healthcare resource utilization and medical costs during best supportive care after the last anticancer drug treatment in patients with terminal cancer. Majority of patients were hospitalized and the length of hospitalization had the greatest impact on total medical costs. Pancreatic cancer had the highest proportion of hospitalized patients and the highest medical cost. An alternative system for hospitalization should be developed to support patients with terminal cancer.
