期刊
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
卷 7, 期 15, 页码 13497-13504出版社
AMER CHEMICAL SOC
DOI: 10.1021/acssuschemeng.9b02966
关键词
Lignin; Nanoparticles; Pickering emulsions; Drug delivery; Renewable biopolymer
资金
- National Key Research and Development Program of China [2017YFB0307903]
- National Natural Science Foundation of China [21706193]
- Young Elite Scientists Sponsorship Program by Tianjin [TJSQNTJ-2017-19]
In this work, we designed a novel multifunctional Pickering emulsion stabilized by lignin-based nanoparticles. We utilized the industrial waste lignin to prepare thermoresponsive lignin copolymer by grafting poly(N-isopropylacrylamide) (PNIPAM) onto lignin via atom transfer radical polymerization (ATRP) and then formed self-assembled nanoparticles (AL-g-PNIPAM NPs). AL-g-PNIPAM NPs well stabilized trans-resveratrol (trans-RSV)-containing palm oil emulsion droplets in water. Thanks to the abundant UV chromophoric groups of lignin, the light stability of trans-RSV was significantly improved by the protecting of the AL-g-PNIPAM NPs layer. Moreover, the emulsion properties and release behavior strongly depend on the temperature and nanoparticles size: decreasing temperature induced deformation of AL-g-PNIPAM NPs at the interface, an increase in droplet size, and the accelerated release of trans-RSV. These results showed the great potential of this approach of a green functional lignin-based nanoparticles stabilized Pickering emulsion for storage and thermal-controlled release of light-unstable and poorly water-soluble drugs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据