Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli

Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase

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Secondary Metabolites from an Endophytic Fungus Nigrospora sp.

(2016) Rong Huang et al.   CHEMISTRY OF NATURAL COMPOUNDS

Evolutionary distinctiveness of fatty acid and polyketide synthesis in eukaryotes

(2016) Gurjeet S Kohli et al.   ISME Journal

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization

(2016) Scott Griffiths et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation

(2016) Jonathan Latham et al.   Nature Communications

Metabolic Profiling of Geobacter sulfurreducens during Industrial Bioprocess Scale-Up

(2015) Howbeer Muhamadali et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Minimum Information about a Biosynthetic Gene cluster

(2015) Marnix H Medema et al.   Nature Chemical Biology

Reinvigorating natural product combinatorial biosynthesis with synthetic biology

(2015) Eunji Kim et al.   Nature Chemical Biology

Evolution of chemical diversity by coordinated gene swaps in type II polyketide gene clusters

(2015) Maureen E. Hillenmeyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

Versatility of Acyl-Acyl Carrier Protein Synthetases

(2014) Joris Beld et al.   CHEMISTRY & BIOLOGY

The Determinants of Activity and Specificity in Actinorhodin Type II Polyketide Ketoreductase

(2013) Pouya Javidpour et al.   CHEMISTRY & BIOLOGY

Steps towards the synthetic biology of polyketide biosynthesis

(2013) Matthew Cummings et al.   FEMS MICROBIOLOGY LETTERS

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(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

ATP Citrate Lyase Mediates Resistance of Colorectal Cancer Cells to SN38

(2013) Y. Zhou et al.   MOLECULAR CANCER THERAPEUTICS

Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites

(2013) Amin Espah Borujeni et al.   NUCLEIC ACIDS RESEARCH

Alternative Sigma Factor Over-Expression Enables Heterologous Expression of a Type II Polyketide Biosynthetic Pathway in Escherichia coli

(2013) David Cole Stevens et al.   PLoS One

ATP citrate lyase knockdown impacts cancer stem cells in vitro

(2013) J-i Hanai et al.   Cell Death & Disease

Identification of new dianthrone glycosides from Polygonum multiflorum Thunb. using high-performance liquid chromatography coupled with LTQ-Orbitrap mass spectrometry detection: a strategy for the rapid detection of new low abundant metabolites from traditional Chinese medicines

(2012) Wen Xu et al.   Analytical Methods

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Engineered biosynthesis of the antiparasitic agent frenolicin B and rationally designed analogs in a heterologous host

(2011) Jay T Fitzgerald et al.   JOURNAL OF ANTIBIOTICS

Completing the puzzle of aurachin biosynthesis in Stigmatella aurantiaca Sg a15

(2011) Dominik Pistorius et al.   Molecular BioSystems

Engineered polyketide biosynthesis and biocatalysis in Escherichia coli

(2010) Xue Gao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biosynthesis of Aromatic Polyketides in Bacteria

(2009) Abhirup Das et al.   ACCOUNTS OF CHEMICAL RESEARCH

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Emergent gene order in a model of modular polyketide synthases

(2009) B. Callahan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Octaketide-producing type III polyketide synthase from Hypericum perforatum is expressed in dark glands accumulating hypericins

(2008) Katja Karppinen et al.   FEBS Journal

Orchestration of Discoid Polyketide Cyclization in the Resistomycin Pathway

(2008) Kathrin Fritzsche et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rare Codons Cluster

(2008) Thomas F. Clarke et al.   PLoS One

Evolution of polyketide synthases in bacteria

(2008) C. P. Ridley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli

(2008) W. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redirecting the Cyclization Steps of Fungal Polyketide Synthase

(2007) Suzanne M. Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY