Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties

Hypoxic glioblastoma release exosomal VEGF-A induce the permeability of blood-brain barrier

(2018) Chen Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Revealing the glioma cancer stem cell interactome, one niche at a time

(2018) Daniel J Silver et al.   JOURNAL OF PATHOLOGY

Collagen Fiber Orientation Regulates 3D Vascular Network Formation and Alignment

(2018) Michael G. McCoy et al.   ACS Biomaterials-Science & Engineering

Collagen Fiber Orientation Regulates 3D Vascular Network Formation and Alignment

(2018) Michael G. McCoy et al.   ACS Biomaterials Science & Engineering

A three-dimensional (3D) organotypic microfluidic model for glioma stem cells – Vascular interactions

(2018) Danh Truong et al.   BIOMATERIALS

Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration

(2017) Hasini Jayatilaka et al.   Nature Communications

Strain Stiffening of Fibrillar Collagen during Individual and Collective Cell Migration Identified by AFM Nanoindentation

(2016) Sjoerd van Helvert et al.   ACS Applied Materials & Interfaces

Collagen I hydrogel microstructure and composition conjointly regulate vascular network formation

(2016) Michael G. McCoy et al.   Acta Biomaterialia

CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma

(2016) Colin W. Steele et al.   CANCER CELL

Induction of CXCR2 ligands, stem cell-like phenotype, and metastasis in chemotherapy-resistant breast cancer cells

(2016) Bhawna Sharma et al.   CANCER LETTERS

The role of CD44 in glioblastoma multiforme

(2016) Kelly L. Mooney et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Migrating glioma cells express stem cell markers and give rise to new tumors upon xenografting

(2016) Sune Munthe et al.   JOURNAL OF NEURO-ONCOLOGY

3D culture broadly regulates tumor cell hypoxia response and angiogenesis via pro-inflammatory pathways

(2015) Peter DelNero et al.   BIOMATERIALS

Constitutive Activation of Myosin-Dependent Contractility Sensitizes Glioma Tumor-Initiating Cells to Mechanical Inputs and Reduces Tissue Invasion

(2015) S. Y. Wong et al.   CANCER RESEARCH

Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

(2015) Brendon M. Baker et al.   NATURE MATERIALS

Optimum 3D Matrix Stiffness for Maintenance of Cancer Stem Cells Is Dependent on Tissue Origin of Cancer Cells

(2015) Esmaiel Jabbari et al.   PLoS One

Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression

(2014) H.-M. Jeon et al.   CANCER RESEARCH

Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth

(2014) Alexander Pietras et al.   Cell Stem Cell

Serum Interleukin-8 Reflects Tumor Burden and Treatment Response across Malignancies of Multiple Tissue Origins

(2014) M. F. Sanmamed et al.   CLINICAL CANCER RESEARCH

Type 1 collagen as a potential niche component for CD133-positive glioblastoma cells

(2014) Hiroaki Motegi et al.   NEUROPATHOLOGY

Glioblastoma Behaviors in Three-Dimensional Collagen-Hyaluronan Composite Hydrogels

(2013) Shreyas S. Rao et al.   ACS Applied Materials & Interfaces

Glioblastoma Stem Cells Are Regulated by Interleukin-8 Signaling in a Tumoral Perivascular Niche

(2013) D. W. Infanger et al.   CANCER RESEARCH

Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

(2013) Lin Cheng et al.   CELL

CLARITY for mapping the nervous system

(2013) Kwanghun Chung et al.   NATURE METHODS

Astrocytes Enhance the Invasion Potential of Glioblastoma Stem-Like Cells

(2013) Barbara H. Rath et al.   PLoS One

Collagen as a double-edged sword in tumor progression

(2013) Min Fang et al.   TUMOR BIOLOGY

Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis

(2012) Thomas Jamieson et al.   JOURNAL OF CLINICAL INVESTIGATION

The disturbed blood–brain barrier in human glioblastoma

(2012) Hartwig Wolburg et al.   MOLECULAR ASPECTS OF MEDICINE

In vitro microvessels for the study of angiogenesis and thrombosis

(2012) Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and function of ECM-inspired composite collagen type I scaffolds

(2012) Dimitar R. Stamov et al.   Soft Matter

The perivascular niche microenvironment in brain tumor progression

(2010) Nikki A Charles et al.   CELL CYCLE

CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

(2010) Christophe Ginestier et al.   JOURNAL OF CLINICAL INVESTIGATION

Oxygen-Controlled Three-Dimensional Cultures to Analyze Tumor Angiogenesis

(2010) Scott S. Verbridge et al.   TISSUE ENGINEERING PART A

The Interleukin-8 Pathway in Cancer

(2008) D. J.J. Waugh et al.   CLINICAL CANCER RESEARCH

Deregulation of a STAT3-Interleukin 8 Signaling Pathway Promotes Human Glioblastoma Cell Proliferation and Invasiveness

(2008) N. de la Iglesia et al.   JOURNAL OF NEUROSCIENCE

Glioma Formation, Cancer Stem Cells, and Akt Signaling

(2008) Dolores Hambardzumyan et al.   Stem Cell Reviews and Reports

ALDH1 as a Functional Marker of Cancer Stem and Progenitor Cells

(2008) Julie Douville et al.   STEM CELLS AND DEVELOPMENT

Endothelial Cells Enhance Tumor Cell Invasion through a Crosstalk Mediated by CXC Chemokine Signaling

(2008) Kristy A. Warner et al.   NEOPLASIA

Expression of matrix metalloproteinases MMP-1, MMP-11 and MMP-19 is correlated with the WHO-grading of human malignant gliomas

(2007) Jelena Stojic et al.   NEUROSCIENCE RESEARCH