Article
Pharmacology & Pharmacy
Francesco Di Pierro, Ruqqia Sultana, Amna Zia Eusaph, Saida Abrar, Mahroo Bugti, Fauzia Afridi, Umer Farooq, Somia Iqtadar, Fareeha Ghauri, Syeda Makhduma, Shazia Nourin, Ayesha Kanwal, Aasiya Bano, Ali Akbar Bugti, Shah Mureed, Ayesha Ghazal, Romana Irshad, Martino Recchia, Alexander Bertuccioli, Pietro Putignano, Antonella Riva, Luigina Guasti, Nicola Zerbinati, Amjad Khan
Summary: A multi-centric, randomized, controlled and prospective study found that supplementation with Berberine Phytosome (BP), a more easily absorbed form of berberine, can improve menstrual and ovary abnormalities in women with polycystic ovary syndrome (PCOS), with good tolerability and safety.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Nutrition & Dietetics
Jessica M. Moon, Kayla M. Ratliff, Anthony M. Hagele, Richard A. Stecker, Petey W. Mumford, Chad M. Kerksick
Summary: This study aimed to determine the rate and extent of absorption of berberine or dihydroberberine after oral ingestion. The results showed that four doses of 100 mg or 200 mg dihydroberberine significantly increased plasma berberine concentration within a two-hour window, while 500 mg berberine or placebo did not show this effect.
Article
Biochemistry & Molecular Biology
Lea Sani, Nicolas Cardinault, Julien Astier, Patrice Darmon, Jean Francois Landrier
Summary: This study aimed to evaluate the effect of supplementation with standardized poplar propolis extract powder (PPEP) on insulin homeostasis in non-diabetic insulin-resistant volunteers with obesity. The results showed that PPEP supplementation improved insulin sensitivity by reducing the number of insulin-resistant subjects and decreasing the insulin sensitivity Matsuda index (ISI-M).
Article
Nutrition & Dietetics
Louise Kjolbaek, Jesper M. Schmidt, Emilien Rouy, Klaus J. Jensen, Arne Astrup, Hanne C. Bertram, Marianne Hammershoj, Anne Raben
Summary: This study investigated the effects of different dairy matrices on postprandial lipid, glycemic, and appetite responses over 8 hours. The results showed that different dairy products with varying matrices had an impact on lipid responses, but had minimal effects on apoB-48 responses.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Multidisciplinary Sciences
Paniz Anvarifard, Alireza Ostadrahimi, Mohammadreza Ardalan, Maryam Anbari, Zohreh Ghoreishi
Summary: This study aimed to evaluate the efficacy of propolis on various parameters in patients with CKD. The results showed that propolis supplementation significantly improved the health-related quality of life in CKD patients, but had no significant effects on other parameters such as kidney function and blood pressure.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Medicinal
Reza Goodarzi, Sima Jafarirad, Narges Mohammadtaghvaei, Maryam Dastoorpoor, Pejman Alavinejad
Summary: The study demonstrated that pomegranate extract could reduce total cholesterol, triglycerides, weight, and other indicators in NAFLD patients, while also increasing serum HDL-C levels. Therefore, pomegranate extract can be used as a complementary therapy to improve physiological indicators in patients with NAFLD.
PHYTOTHERAPY RESEARCH
(2021)
Article
Multidisciplinary Sciences
Zhibo Xie, Yuning Sun, Yuqian Ye, Dandan Hu, Hua Zhang, Zhangyuting He, Haitao Zhao, Huayu Yang, Yilei Mao
Summary: Time-restricted feeding, both early (eTRF) and mid-day (mTRF), have been shown to have metabolic benefits. A randomized controlled trial comparing the effects of eTRF and mTRF in healthy non-obese individuals found that eTRF was more effective in improving insulin sensitivity and other metabolic parameters.
NATURE COMMUNICATIONS
(2022)
Article
Nutrition & Dietetics
Maha H. Alhussain, Ian A. Macdonald, Moira A. Taylor
Summary: The study revealed that in women who are overweight or with obesity and confirmed insulin resistance, irregular meal patterns may lead to a decrease in thermic effect of food, influence insulin and glucose metabolism, and affect appetite regulation.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Food Science & Technology
Fei Au-Yeung, Alexandra L. Jenkins, Steve Prancevic, Esther Vissers, Janice E. Campbell, Thomas M. S. Wolever
Summary: Allulose is a naturally occurring monosaccharide that is about 70% as sweet as sucrose, and consuming it with a carbohydrate-containing meal may help to reduce postprandial glucose levels. It is unclear whether a higher ratio of allulose to carbohydrates can further inhibit both glycemic and insulin responses.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Nutrition & Dietetics
Max L. Eckstein, Antonia Brockfeld, Sandra Haupt, Janis R. Schierbauer, Rebecca T. Zimmer, Nadine Wachsmuth, Beate Zunner, Paul Zimmermann, Barbara Obermayer-Pietsch, Othmar Moser
Summary: The study found that fructose led to lower peak blood glucose levels compared to glucose and glucose and fructose supplementation, with no significant difference between glucose and glucose and fructose supplementation in terms of peak values. Additionally, all conditions resulted in significantly higher peak blood glucose values compared to sucralose.
Article
Biochemistry & Molecular Biology
Delia Pei Shan Lee, Alicia Xinli Gan, Clarinda Nataria Sutanto, Kate Qi Xuan Toh, Chin Meng Khoo, Jung Eun Kim
Summary: This study assessed the postprandial glycemic and lipid effects in middle-aged and older Singaporeans following consumption of biscuits containing okara and biovalorized okara. The results showed that biovalorized okara lowered insulin secretion, while okara improved insulin sensitivity. Additionally, biovalorized okara led to higher levels of short-chain fatty acids. However, these biscuits did not significantly affect blood glucose, total cholesterol, HDL-cholesterol, and triglyceride concentrations. Biovalorized okara was preferred in terms of flavor and overall liking.
Article
Cardiac & Cardiovascular Systems
Chiao-Nan Chen, Kuo-Jen Hsu, Kuei-Yu Chien, Jeu-Jung Chen
Summary: This study investigated the effects of exercise alone or in combination with a high-protein diet on markers of cardiometabolic health in middle-aged adults with obesity. The results showed that the combined intervention significantly decreased fat mass and improved lipid profiles, insulin sensitivity, glucose tolerance, and inflammation in this population, highlighting the importance of lifestyle modifications in managing obesity-related health risks.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Nutrition & Dietetics
Stefan Kabisch, Nina M. T. Meyer, Caroline Honsek, Margrit Kemper, Christiana Gerbracht, Ayman M. Arafat, Ulrike Dambeck, Martin A. Osterhoff, Martin O. Weickert, Andreas F. H. Pfeiffer
Summary: This study found that higher post-challenge glucose levels strongly predict the metabolic non-response in a complex lifestyle intervention. Fasting glucose levels and insulin sensitivity may contribute to the risk pattern, while improvement in beta-cell function may qualify as a potential risk factor for non-response. The study could not replicate previous data suggesting that insulin-resistant fatty liver is a specific risk factor for treatment failure.
Article
Endocrinology & Metabolism
Alessandra Celli, Yoann Barnouin, Bryan Jiang, Dean Blevins, Georgia Colleluori, Sanjay Mediwala, Reina Armamento-Villareal, Clifford Qualls, Dennis T. Villareal
Summary: A lifestyle intervention strategy is highly successful in improving metabolic and functional health of older adults with diabetes.
Article
Medicine, General & Internal
Gladys Maribel Hidalgo-Lozada, Angelica Villarruel-Lopez, Esperanza Martinez-Abundis, Olga Vazquez-Paulino, Manuel Gonzalez-Ortiz, Karina Griselda Perez-Rubio
Summary: The study found that ellagic acid (EA) has a positive effect on the components of metabolic syndrome (MetS), reducing hyperinsulinemia and improving insulin sensitivity.
JOURNAL OF CLINICAL MEDICINE
(2022)