Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution
出版年份 2019 全文链接
标题
Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-07-19
DOI
10.1038/s41467-019-11155-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes
- (2019) Ge Qu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Directed Evolution of Protein Catalysts
- (2018) Cathleen Zeymer et al. Annual Review of Biochemistry
- Distinct Roles of Catalytic Cysteine and Histidine in the Protease and Ligase Mechanisms of Human Legumain As Revealed by DFT-Based QM/MM Simulations
- (2017) Brigitta Elsässer et al. ACS Catalysis
- Quantum Mechanics/Molecular Mechanics Insights into the Enantioselectivity of the O-Acetylation of (R,S)-Propranolol Catalyzed by Candida antarctica Lipase B
- (2016) Andrés M. Escorcia et al. ACS Catalysis
- Stepwise Versus Concerted Mechanisms in General-Base Catalysis by Serine Proteases
- (2015) Neta Uritsky et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- New insights in the catalytic mechanism of tyrosine ammonia-lyase given by QM/MM and QM cluster models
- (2015) Gaspar P. Pinto et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Interfacial Activation of Candida antarctica Lipase B: Combined Evidence from Experiment and Simulation
- (2015) Themistoklis Zisis et al. BIOCHEMISTRY
- Open and closed states ofCandida antarcticalipase B: protonation and the mechanism of interfacial activation
- (2015) Benjamin Stauch et al. JOURNAL OF LIPID RESEARCH
- Combined Quantum Mechanics/Molecular Mechanics (QM/MM) Methods in Computational Enzymology
- (2013) Marc W. van der Kamp et al. BIOCHEMISTRY
- Reaction Pathway and Free Energy Profile for Papain-Catalyzed Hydrolysis of N-Acetyl-Phe-Gly 4-Nitroanilide
- (2013) Donghui Wei et al. BIOCHEMISTRY
- Regulation of A20 and other OTU deubiquitinases by reversible oxidation
- (2013) Yogesh Kulathu et al. Nature Communications
- Theoretical Study of Primary Reaction of Pseudozyma antarctica Lipase B as the Starting Point To Understand Its Promiscuity
- (2013) Katarzyna Świderek et al. ACS Catalysis
- Lipase B from Candida antarctica binds to hydrophobic substrate–water interfaces via hydrophobic anchors surrounding the active site entrance
- (2012) Christian C. Gruber et al. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
- An overview of the Amber biomolecular simulation package
- (2012) Romelia Salomon-Ferrer et al. Wiley Interdisciplinary Reviews-Computational Molecular Science
- New families of carboxyl peptidases: serine-carboxyl peptidases and glutamic peptidases
- (2011) K. Oda JOURNAL OF BIOCHEMISTRY
- MEROPS: the database of proteolytic enzymes, their substrates and inhibitors
- (2011) N. D. Rawlings et al. NUCLEIC ACIDS RESEARCH
- Integration, scaling, space-group assignment and post-refinement
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- QM/MM Methods for Biomolecular Systems
- (2009) Hans Martin Senn et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Understanding the Plasticity of the α/β Hydrolase Fold: Lid Swapping on theCandida antarcticaLipase B Results in Chimeras with Interesting Biocatalytic Properties
- (2009) Michael Skjøt et al. CHEMBIOCHEM
- Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates
- (2008) Joaquin Sanchis et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Unconventional serine proteases: Variations on the catalytic Ser/His/Asp triad configuration
- (2008) Özlem Doğan Ekici et al. PROTEIN SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now