Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

(2019) Alexandra C. Walls et al.   CELL

Ultrapotent Human Neutralizing Antibody Repertoires Against Middle East Respiratory Syndrome Coronavirus From a Recovered Patient

(2018) Peihua Niu et al.   JOURNAL OF INFECTIOUS DISEASES

Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape

(2018) Lingshu Wang et al.   JOURNAL OF VIROLOGY

Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein

(2018) Senyan Zhang et al.   Cell Reports

A Human DPP4-Knockin Mouse’s Susceptibility to Infection by Authentic and Pseudotyped MERS-CoV

(2018) Changfa Fan et al.   Viruses-Basel

Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2

(2018) Wenfei Song et al.   PLoS Pathogens

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

(2017) Jesper Pallesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains

(2017) Yuan Yuan et al.   Nature Communications

Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding

(2016) Miao Gui et al.   CELL RESEARCH

Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)–Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection

(2016) Katherine V. Houser et al.   JOURNAL OF INFECTIOUS DISEASES

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

(2016) Alexandra C. Walls et al.   NATURE

Pre-fusion structure of a human coronavirus spike protein

(2016) Robert N. Kirchdoerfer et al.   NATURE

3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012

(2016) Reed F. Johnson et al.   VIROLOGY

Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection

(2016) Anurodh Shankar Agrawal et al.   Scientific Reports

Automatic crystal centring procedure at the SSRF macromolecular crystallography beamline

(2016) Zhijun Wang et al.   JOURNAL OF SYNCHROTRON RADIATION

A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein

(2015) Yan Li et al.   CELL RESEARCH

Environmental Contamination and Viral Shedding in MERS Patients During MERS-CoV Outbreak in South Korea

(2015) Seo Yu Bin et al.   CLINICAL INFECTIOUS DISEASES

Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection

(2015) Rudragouda Channappanavar et al.   JOURNAL OF INFECTIOUS DISEASES

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

(2015) Davide Corti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

(2015) Kristen E. Pascal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody

(2015) Tianlei Ying et al.   Nature Communications

Evaluation of candidate vaccine approaches for MERS-CoV

(2015) Lingshu Wang et al.   Nature Communications

History of passive antibody administration for prevention and treatment of infectious diseases

(2015) Barney S. Graham et al.   Current Opinion in HIV and AIDS

Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27

(2015) Xiaojuan Yu et al.   Scientific Reports

Improving Neutralization Potency and Breadth by Combining Broadly Reactive HIV-1 Antibodies Targeting Major Neutralization Epitopes

(2014) Rui Kong et al.   JOURNAL OF VIROLOGY

Exceptionally Potent Neutralization of Middle East Respiratory Syndrome Coronavirus by Human Monoclonal Antibodies

(2014) Tianlei Ying et al.   JOURNAL OF VIROLOGY

A Conformation-Dependent Neutralizing Monoclonal Antibody Specifically Targeting Receptor-Binding Domain in Middle East Respiratory Syndrome Coronavirus Spike Protein

(2014) L. Du et al.   JOURNAL OF VIROLOGY

Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

(2014) Jean Kaoru Millet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution

(2014) X.-C. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

(2014) J. B. Munro et al.   SCIENCE

Potent Neutralization of MERS-CoV by Human Neutralizing Monoclonal Antibodies to the Viral Spike Glycoprotein

(2014) L. Jiang et al.   Science Translational Medicine

Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus

(2014) M. Cotten et al.   mBio

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

(2013) Nianshuang Wang et al.   CELL RESEARCH

The emerging novel Middle East respiratory syndrome coronavirus: The “knowns” and “unknowns”

(2013) Jasper Fuk-Woo Chan et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation

(2013) Bart L Haagmans et al.   LANCET INFECTIOUS DISEASES

Crystal Structure of Bovine Coronavirus Spike Protein Lectin Domain

(2012) Guiqing Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

(2012) Florian Klein et al.   NATURE

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Monoclonal Antibodies against Highly Conserved HR1 and HR2 Domains of the SARS-CoV Spike Protein Are More Broadly Neutralizing

(2012) Hatem A. Elshabrawy et al.   PLoS One

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor

(2011) G. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Two-Step Conformational Changes in a Coronavirus Envelope Glycoprotein Mediated by Receptor Binding and Proteolysis

(2009) S. Matsuyama et al.   JOURNAL OF VIROLOGY