F-box protein FBXO30 mediates retinoic acid receptor γ ubiquitination and regulates BMP signaling in neural tube defects

Physiological functions of FBW7 in cancer and metabolism

(2018) Kouhei Shimizu et al.   CELLULAR SIGNALLING

Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis

(2018) Scott A. Rankin et al.   DEVELOPMENTAL BIOLOGY

Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

(2018) Andreas Sagner et al.   PLOS BIOLOGY

Transcriptomic profile analysis of mouse neural tube development by RNA-Seq

(2017) Juan Yu et al.   IUBMB LIFE

Roles of Retinoic Acid Signaling in Shaping the Neuronal Architecture of the Developing Amphioxus Nervous System

(2017) Elisabeth Zieger et al.   MOLECULAR NEUROBIOLOGY

Neural tube defects: Risk factors and preventive measures

(2017) Atsuo Kondo et al.   CONGENITAL ANOMALIES

The SCF-type E3 Ubiquitin Ligases as Cancer Targets

(2016) Kyoko Kitagawa et al.   CURRENT CANCER DRUG TARGETS

The E3 ubiquitin protein ligase MDM2 dictates all-trans retinoic acid-induced osteoblastic differentiation of osteosarcoma cells by modulating the degradation of RARα

(2016) M Ying et al.   ONCOGENE

Anterior-Posterior Patterning of Definitive Endoderm Generated from Human Embryonic Stem Cells Depends on the Differential Signaling of Retinoic Acid, Wnt-, and BMP-Signaling

(2016) Claudia Davenport et al.   STEM CELLS

Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5

(2016) Yan Liu et al.   Cell Reports

F-box protein Fbxo3 targets Smurf1 ubiquitin ligase for ubiquitination and degradation

(2015) Dongnian Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms of retinoic acid signalling and its roles in organ and limb development

(2015) Thomas J. Cunningham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genetic, Epigenetic, and Environmental Contributions to Neural Tube Closure

(2014) Jonathan J. Wilde et al.   Annual Review of Genetics

Neural Tube Defects

(2014) Nicholas D.E. Greene et al.   Annual Review of Neuroscience

Identification of Novel CELSR1 Mutations in Spina Bifida

(2014) Yunping Lei et al.   PLoS One

Selective Small Molecule Compounds Increase BMP-2 Responsiveness by Inhibiting Smurf1-mediated Smad1/5 Degradation

(2014) Yu Cao et al.   Scientific Reports

RA and FGF Signalling Are Required in the Zebrafish Otic Vesicle to Pattern and Maintain Ventral Otic Identities

(2014) Esther C. Maier et al.   PLoS Genetics

A Dominant Mutation in FBXO38 Causes Distal Spinal Muscular Atrophy with Calf Predominance

(2013) Charlotte J. Sumner et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Retinoic acid signaling pathways in development and diseases

(2013) Bhaskar C. Das et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Neural tube defects: recent advances, unsolved questions, and controversies

(2013) Andrew J Copp et al.   LANCET NEUROLOGY

BMP signaling controls muscle mass

(2013) Roberta Sartori et al.   NATURE GENETICS

Detection of Copy Number Variants Reveals Association of Cilia Genes with Neural Tube Defects

(2013) Xiaoli Chen et al.   PLoS One

BMP-Smad 1/5/8 signalling in the development of the nervous system

(2013) Shane V. Hegarty et al.   PROGRESS IN NEUROBIOLOGY

The Continuing Challenge of Understanding, Preventing, and Treating Neural Tube Defects

(2013) J. B. Wallingford et al.   SCIENCE

Retinoic acid signalling during development

(2012) M. Rhinn et al.   DEVELOPMENT

Synaptic retinoic acid signaling and homeostatic synaptic plasticity

(2012) Lu Chen et al.   NEUROPHARMACOLOGY

SFRP1 and SFRP2 Dose-Dependently Regulate Midbrain Dopamine Neuron Development In Vivo and in Embryonic Stem Cells

(2012) Julianna Kele et al.   STEM CELLS

A vitamin for the brain

(2012) Kirsty D. Shearer et al.   TRENDS IN NEUROSCIENCES

SCFFBXL15regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1

(2011) Yu Cui et al.   EMBO JOURNAL

Regulation of cell fate determination by Skp1-Cullin1-F-box (SCF) E3 ubiquitin ligases

(2011) Christopher J. Hindley et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Genetic deletion of Cyp26b1 negatively impacts limb skeletogenesis by inhibiting chondrogenesis

(2011) H. J. Dranse et al.   JOURNAL OF CELL SCIENCE

Global DNA hypomethylation is associated with NTD-affected pregnancy: A case-control study

(2010) Xiaoli Chen et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Analysis of Cyp26b1/Rarg compound-null mice reveals two genetically separable effects of retinoic acid on limb outgrowth

(2010) Tracie Pennimpede et al.   DEVELOPMENTAL BIOLOGY

Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1

(2010) N. Sheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SnapShot: F Box Proteins I

(2009) Jeffrey R. Skaar et al.   CELL

Control of cell growth by the SCF and APC/C ubiquitin ligases

(2009) Jeffrey R Skaar et al.   CURRENT OPINION IN CELL BIOLOGY

A Sonic Hedgehog Missense Mutation Associated with Holoprosencephaly Causes Defective Binding to GAS1

(2009) David C. Martinelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fbxo45 Forms a Novel Ubiquitin Ligase Complex and Is Required for Neuronal Development

(2009) T. Saiga et al.   MOLECULAR AND CELLULAR BIOLOGY

Retinoic Acid Synthesis and Signaling during Early Organogenesis

(2008) Gregg Duester   CELL

All-trans-retinoic acid alters Smads expression in embryonic neural tissue of mice

(2008) Juntao Zhang et al.   JOURNAL OF APPLIED TOXICOLOGY